Viral Polymerases

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  • Publisher : Academic Press
  • Release : 29 October 2018
  • ISBN : 9780128154236
  • Page : 496 pages
  • Rating : 4.5/5 from 103 voters

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Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs. Provides comprehensive, state-of-the-art coverage on virus infections, the virus lifecycle, and mechanisms of polymerase inhibition Analyzes the structure-activity relationships of inhibitors of each viral polymerase Presents a consistent and comprehensive coverage of all aspects of viral polymerases, including structure, function and their role as antiviral drug targets

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Viral Polymerases

Viral Polymerases
  • Author : Satya Prakash Gupta
  • Publisher : Academic Press
  • Release Date : 2018-10-29
  • ISBN : 9780128154236
GET THIS BOOKViral Polymerases

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent

Viral Polymerases and Related Proteins

Viral Polymerases and Related Proteins
  • Author : Lawrence C. Kuo,David B. Olsen,Steven S. Carroll
  • Publisher : Elsevier
  • Release Date : 1996
  • ISBN : 0121821765
GET THIS BOOKViral Polymerases and Related Proteins

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Expression, purification, and characterization *

Nucleic Acid Polymerases

Nucleic Acid Polymerases
  • Author : Katsuhiko S. Murakami,Michael A. Trakselis
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-22
  • ISBN : 9783642397967
GET THIS BOOKNucleic Acid Polymerases

This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle

Human Herpesviruses

Human Herpesviruses
  • Author : Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
  • Publisher : Cambridge University Press
  • Release Date : 2007-08-16
  • ISBN : 9781139461641
GET THIS BOOKHuman Herpesviruses

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • ISBN : 0815332181
GET THIS BOOKMolecular Biology of the Cell

Structural and Functional Characterization of Escherichia Coli RNA Polymerase Ternary Complexes During Transcript Elongation and Termination

Structural and Functional Characterization of Escherichia Coli RNA Polymerase Ternary Complexes During Transcript Elongation and Termination
  • Author : Susan Marie Uptain
  • Publisher : Unknown
  • Release Date : 1997
  • ISBN : UCAL:C3409130
GET THIS BOOKStructural and Functional Characterization of Escherichia Coli RNA Polymerase Ternary Complexes During Transcript Elongation and Termination

Viral Replication Enzymes and their Inhibitors Part A

Viral Replication Enzymes and their Inhibitors Part A
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-10-23
  • ISBN : 9780128234693
GET THIS BOOKViral Replication Enzymes and their Inhibitors Part A

Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series

DNA Polymerases

DNA Polymerases
  • Author : Anonim
  • Publisher : World Scientific
  • Release Date : 2010
  • ISBN : 9789814465458
GET THIS BOOKDNA Polymerases

Origin and Evolution of Viruses

Origin and Evolution of Viruses
  • Author : Esteban Domingo,Colin R. Parrish,John J. Holland
  • Publisher : Elsevier
  • Release Date : 2008-06-23
  • ISBN : 0080564968
GET THIS BOOKOrigin and Evolution of Viruses

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their

RNA GENETICS DIR VIRUS REPLIC

RNA GENETICS DIR VIRUS REPLIC
  • Author : John J. Holland,Paul Ahlquist
  • Publisher : CRC PressI Llc
  • Release Date : 1988-05-31
  • ISBN : UOM:39015012650829
GET THIS BOOKRNA GENETICS DIR VIRUS REPLIC

Antiviral Mechanisms in the Control of Neoplasia

Antiviral Mechanisms in the Control of Neoplasia
  • Author : P. Chandra
  • Publisher : Springer
  • Release Date : 1979-02
  • ISBN : UCAL:B4425384
GET THIS BOOKAntiviral Mechanisms in the Control of Neoplasia

Textbook of Influenza

Textbook of Influenza
  • Author : Robert G. Webster,Arnold S. Monto,Thomas J. Braciale,Robert A. Lamb
  • Publisher : John Wiley & Sons
  • Release Date : 2014-01-06
  • ISBN : 9781118636831
GET THIS BOOKTextbook of Influenza

The Textbook of Influenza is a comprehensive resourcecovering all aspects of influenza, from the genetic and molecularbiology of the virus through to clinical aspects of the disease andthe latest drug developments and treatments. This new edition hasbeen completely revised and reflects the integration of disciplinesconcerning the emergence, evolution, pathogenesis and control ofinfluenza viruses in the field of human and veterinary publichealth. Textbook of Influenza examines the lessons learnt fromthe latest pandemic and provides the current state of knowledge formany yet

Viral Molecular Machines

Viral Molecular Machines
  • Author : Michael G. Rossmann,Venigalla B. Rao
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-02-02
  • ISBN : 9781461409809
GET THIS BOOKViral Molecular Machines

This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes

The DNA Replication Machinery as Therapeutic Targets

The DNA Replication Machinery as Therapeutic Targets
  • Author : Andrew F. Gardner,Zvi Kelman
  • Publisher : Frontiers Media SA
  • Release Date : 2019-09-19
  • ISBN : 9782889459278
GET THIS BOOKThe DNA Replication Machinery as Therapeutic Targets

In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins

The Biology of RNA-tumor Viruses

The Biology of RNA-tumor Viruses
  • Author : Howard M. Temin
  • Publisher : Unknown
  • Release Date : 1974
  • ISBN : UOM:39015003214114
GET THIS BOOKThe Biology of RNA-tumor Viruses