Tumor Vascularization

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  • Publisher : Academic Press
  • Release : 21 January 2020
  • ISBN : 9780128194942
  • Page : 198 pages
  • Rating : 4.5/5 from 103 voters

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Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels. Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

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Tumor Vascularization

Tumor Vascularization
  • Author : Domenico Ribatti,Francesco Pezzella
  • Publisher : Academic Press
  • Release Date : 2020-01-21
  • ISBN : 9780128194942
GET THIS BOOKTumor Vascularization

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a

Tumour Angiogenesis

Tumour Angiogenesis
  • Author : R. John Bicknell,Claire E. Lewis,Napoleone Ferrara
  • Publisher : Oxford University Press, USA
  • Release Date : 1997
  • ISBN : UOM:39015041324271
GET THIS BOOKTumour Angiogenesis

This is the first comprehensive book to cover all areas of a rapidly expanding research area. Each chapter is written by world experts in the field and topics covered include in vivo models, mechanisms, inhibition, and the role of macrophages, cytokines, proteases, extracellular matrix components, nitric oxide, prostanoids and oncogenes/tumour suppressor genes in angiogenesis. Other chapters examine the role of specific growth factors in angiogenesis, including vascular endothelial growth factor, the basic fibroblast growth factor family, transforming growth factor-beta,

Tumor Vessels as Directors of the Tumor Microenvironment: New Findings, Current Challenges & Perspectives

Tumor Vessels as Directors of the Tumor Microenvironment: New Findings, Current Challenges & Perspectives
  • Author : Lucas Treps,Ann Ager,Kyoko Hida,Kairbaan Hodivala-Dilke
  • Publisher : Frontiers Media SA
  • Release Date : 2022-04-22
  • ISBN : 9782889749669
GET THIS BOOKTumor Vessels as Directors of the Tumor Microenvironment: New Findings, Current Challenges & Perspectives

Tumor Angiogenesis

Tumor Angiogenesis
  • Author : Dieter Marmé,Norbert Fusenig
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-12-05
  • ISBN : 9783540331773
GET THIS BOOKTumor Angiogenesis

Tumor angiogenesis is one of the most prominent mechanisms driving tumor development and progression. This book is written by internationally renowned experts. Part 1 describes the basic mechanisms. Tumor-angiogenic signaling pathways are presented as new potential targets for anti-angiogenic therapy. Part 2 reviews the efforts made to validate new targets and to show efficacy in animals. Part 3 is devoted to the clinical development of the novel anti-angiogenic drugs and their use in clinical practice.

Proteases and Their Inhibitors in Cancer Metastasis

Proteases and Their Inhibitors in Cancer Metastasis
  • Author : J-M. Foidart,R.J. Muschel
  • Publisher : Springer Science & Business Media
  • Release Date : 2002
  • ISBN : 9781402009235
GET THIS BOOKProteases and Their Inhibitors in Cancer Metastasis

In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor biology. The first part provides the reader with a selective overview of the molecular biology of serine proteases, MMPs and their physiological inhibitors. The most important proteases and their physiological as

In Vivo Models to Study Angiogenesis

In Vivo Models to Study Angiogenesis
  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Release Date : 2017-08-18
  • ISBN : 9780128140215
GET THIS BOOKIn Vivo Models to Study Angiogenesis

In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents

Diagnostics of Vascular Diseases

Diagnostics of Vascular Diseases
  • Author : Peter Lanzer,Martin Lipton
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9783642605123
GET THIS BOOKDiagnostics of Vascular Diseases

This textbook systematically reviews the working principles and modes of application of techniques applicable to noninvasive and invasive vascular examinations. The authors cover the essential physical and/or chemical principles of each diagnostic modality and so derive the characteristics of the diagnostic instrumentation. Physicians thus learn how to translate advanced technology into optimum diagnostic efficacy in daily clinical routine.

Tumor Progression and Metastasis

Tumor Progression and Metastasis
  • Author : Anonim
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-04-08
  • ISBN : 9781789853490
GET THIS BOOKTumor Progression and Metastasis

This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the

Ultrasonography in Vascular Diagnosis

Ultrasonography in Vascular Diagnosis
  • Author : Wilhelm Schäberle
  • Publisher : Springer
  • Release Date : 2018-08-15
  • ISBN : 9783319649979
GET THIS BOOKUltrasonography in Vascular Diagnosis

Der Band fasst die modernen Verfahren und neuesten Erkenntnisse auf dem Gebiet der Gefäßdiagnostik zusammen. Der Textteil beschreibt die Gefäßregion mit Sonoanatomie, Untersuchungsablauf und Normalbefund sowie die Indikation der Ultraschalluntersuchung und die klinische Relevanz der Untersuchungsergebnisse. Der Atlasteil veranschaulicht anhand aussagekräftiger Ultraschallbilder die verschiedenen Krankheitsbilder. Die 3. Auflage behandelt verstärkt die Bedeutung der Ultraschall-Routinediagnostik für seltene Gefäßerkrankungen.

Biophysical Regulation of Vascular Differentiation and Assembly

Biophysical Regulation of Vascular Differentiation and Assembly
  • Author : Sharon Gerecht
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-01-06
  • ISBN : 9781441978356
GET THIS BOOKBiophysical Regulation of Vascular Differentiation and Assembly

Because of their ability to differentiate and develop into functional vasculature, stem cells hold tremendous promise for therapeutic applications. However, the scientific understanding and the ability to engineer these cellular systems is still in its early stages, and must advance significantly for the therapeutic potential of stem cells to be realized. Stem cell differentiation and function are exquisitely tuned by their microenvironment. This book will provide a unique perspective of how different aspect of the vasculature microenvironment regulates differentiation and

Biomarkers of the Tumor Microenvironment

Biomarkers of the Tumor Microenvironment
  • Author : Lars A. Akslen,Randolph S. Watnick
  • Publisher : Springer Nature
  • Release Date : 2022-08-13
  • ISBN : 9783030989507
GET THIS BOOKBiomarkers of the Tumor Microenvironment

This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types

Renal and Adrenal Tumors

Renal and Adrenal Tumors
  • Author : E. Löhr,R. Ackerman,D. Bachmann,A. Baert,H. Behrendt,D. Beyer,W. Bischoff,E. Boijsen,H.C. Dominick,V. Fiedler,W.A. Fuchs,M. Georgi,U. Goerttler,M. Goldberg,R. Günther,W. Havers,R. Heckmann,H. Holfeld,L. Jeanmart,J.V. Kaude,L.D. Leder,M. Marberger,G. Marchal,P. Mellin,A. Moss,O. Olsson,M. Osteaux,H.J. Richter,E. Scherer,C. Stambolis,M.W. Strötges,B. Swart,Guido Wilms
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9783642964947
GET THIS BOOKRenal and Adrenal Tumors

The present volume constitutes an attempt to compile contem porary features of diagnosis and treatment of renal and adrenal tumors. A thorough survey of the field is ensured by the authors' considerable scientific experience. Tumors of the kidneys and the adrenal glands are being diagnosed and treated by physicians of different medical disciplines. For both types of tumor, the pathologic cellular substrate is of crucial importance in diagnosis and therapy. In recent years significant diagnostic advances have been made, ranging

Translation and Its Regulation in Cancer Biology and Medicine

Translation and Its Regulation in Cancer Biology and Medicine
  • Author : Armen Parsyan
  • Publisher : Springer
  • Release Date : 2014-10-13
  • ISBN : 9789401790789
GET THIS BOOKTranslation and Its Regulation in Cancer Biology and Medicine

This book, for the first time, comprehensively assembles and analyzes a large body of information on the role of the fundamental mechanism of the protein biosynthesis pathway, translation, in cancer biology. It systematically explores the function of the translation machinery and its regulation, including cell signaling, in the development, maintenance and progression of human cancer. The work presented here unveils the tremendous potential and applications of this vast and exciting branch of genetic, biochemical and molecular science in cancer medicine

Encyclopedic Reference of Vascular Biology & Pathology

Encyclopedic Reference of Vascular Biology & Pathology
  • Author : Andreas Bikfalvi
  • Publisher : Springer
  • Release Date : 2013-12-19
  • ISBN : 9783642570636
GET THIS BOOKEncyclopedic Reference of Vascular Biology & Pathology

This reference provides a synthesis of the whole field of vascular biology, from the latest advances in the study of the structure and function of blood vessels to recent investigations of their interaction with blood cells, with non-cellular constituants of the blood, or with cells of the neighbouring tissue. The latest results from tumor angiogenesis to the latest advances in atherosclerosis research are discussed by leading experts in the field. Together with the CD-ROM this guarantees both researchers and clinicians

Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy

Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy
  • Author : Patrik Andersson,Christian Ostheimer
  • Publisher : Frontiers Media SA
  • Release Date : 2019-12-27
  • ISBN : 9782889631612
GET THIS BOOKCombinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy

The immune system harbors great potential for controlling and eliminating tumors. Recent developments in the field of immuno-oncology has led to unprecedented clinical benefits for a broad spectrum of solid tumors. However, immunotherapy (IT) approaches currently have several limitations including (i) low response rate; (ii) development of resistance and (iii) causing severe immune-related adverse effects (IrAEs), which underline the importance of adequate patient selection. Importantly, IT holds promising synergistic potential when combined with standard-of-care chemotherapy, radiotherapy (RT) and anti-angiogenic therapy (