Translational Immunology

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  • Publisher : Academic Press
  • Release : 18 November 2015
  • ISBN : 9780128017579
  • Page : 384 pages
  • Rating : 4.5/5 from 103 voters

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Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned researchers at the top of their game in their respective fields, in both industry and academic settings. Readers will gain an understanding of the rationale and mechanisms underlying current and emerging pharmacologic approaches for interventional immunology, the gaps therein, and new ideas for better and safer therapeutic approaches, and physicians will glean information about pharmacological limitations in altering disease progression and complications. This reference on the translational realization of the burgeoning findings in immunology provides a go-to reference for experienced professional clinicians, researchers, industry scientists, and those seeking more information on the field. Delivers comprehensive coverage of seminal human immunology discoveries and the resulting impact on therapeutic strategies Presents potential novel targets and approaches for clinical applications in organ specific and systemic autoimmunity, transplant rejection, cancer, and vaccine development Discusses lessons learned from successful and failed clinical trials with specific interventions, including pharmacological issues and limitations, and complications due to immunosuppression Provides information on new strategies and outstanding issues that should be addressed in future research

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Translational Immunology

Translational Immunology
  • Author : Seng-Lai Tan
  • Publisher : Academic Press
  • Release Date : 2015-11-18
  • ISBN : 9780128017579
GET THIS BOOKTranslational Immunology

Translational Immunology: Mechanisms and Pharmacologic Approaches highlights and summarizes the most important advances in human immunology, clinical translations, new tools to analyze therapeutic targets, and new pharmacological approaches for autoimmunity, inflammatory disorders, and cancer. The book is an essential resource for those seeking to understand the potential translational applications of burgeoning studies in human immunology, helping readers make sense of the existing and emerging scientific advances. The book grounds fundamental science in the translational realm, providing insights from world renowned

Cancer Immunology

Cancer Immunology
  • Author : Nima Rezaei
  • Publisher : Springer Nature
  • Release Date : 2020-01-03
  • ISBN : 9783030308452
GET THIS BOOKCancer Immunology

This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-04-01
  • ISBN : 9780323854160
GET THIS BOOKTranslational Autoimmunity

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is

Translational Autoimmunity, Volume 5

Translational Autoimmunity, Volume 5
  • Author : Nima Rezaei
  • Publisher : Elsevier
  • Release Date : 2022-09-23
  • ISBN : 9780323853903
GET THIS BOOKTranslational Autoimmunity, Volume 5

Translational Autoimmunity: Challenges for Autoimmune Diseases, Fifth Edition addresses diagnostic approaches, therapeutic opportunities, and prognostic markers of different autoimmune diseases. This updated volume discusses autotoxicity, systems immunology, the prognostic significance of disease-specific autoantibodies, along with translational research to novel therapeutic policy in autoimmune diseases. From an introduction, to challenges and insights on the systems immunology of infectious and autoimmune diseases, new targets of treatments, and the role of autoantibodies in diagnosis and evolution, this book provides insights on many challenges

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2021-10-22
  • ISBN : 9780128232774
GET THIS BOOKTranslational Autoimmunity

Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-05-01
  • ISBN : 9780323859769
GET THIS BOOKTranslational Autoimmunity

As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases,

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2022-01-21
  • ISBN : 9780323859752
GET THIS BOOKTranslational Autoimmunity

Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases. Covers the clinical aspects

Translational Neuroimmunology in Multiple Sclerosis

Translational Neuroimmunology in Multiple Sclerosis
  • Author : Ruth Arnon,Ariel Miller
  • Publisher : Academic Press
  • Release Date : 2016-05-10
  • ISBN : 9780128020074
GET THIS BOOKTranslational Neuroimmunology in Multiple Sclerosis

Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings

Tumor Immunology and Immunotherapy - Integrated Methods Part A

Tumor Immunology and Immunotherapy - Integrated Methods Part A
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-02-28
  • ISBN : 9780128188750
GET THIS BOOKTumor Immunology and Immunotherapy - Integrated Methods Part A

Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry, High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex

Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors
  • Author : John H. Sampson
  • Publisher : Academic Press
  • Release Date : 2017-02-06
  • ISBN : 9780128026250
GET THIS BOOKTranslational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These

Single Cell Sequencing and Systems Immunology

Single Cell Sequencing and Systems Immunology
  • Author : Xiangdong Wang
  • Publisher : Springer
  • Release Date : 2015-03-27
  • ISBN : 9789401797535
GET THIS BOOKSingle Cell Sequencing and Systems Immunology

The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to

A Year in Review: Discussions in Immunological Memory

A Year in Review: Discussions in Immunological Memory
  • Author : Scott N. Mueller
  • Publisher : Frontiers Media SA
  • Release Date : 2022-11-30
  • ISBN : 9782832507810
GET THIS BOOKA Year in Review: Discussions in Immunological Memory

Paul's Fundamental Immunology

Paul's Fundamental Immunology
  • Author : Martin Flajnik
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2022-07-19
  • ISBN : 9781975142520
GET THIS BOOKPaul's Fundamental Immunology

Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and

Cancer Immunology

Cancer Immunology
  • Author : Nima Rezaei
  • Publisher : Springer
  • Release Date : 2014-12-29
  • ISBN : 9783662449462
GET THIS BOOKCancer Immunology

This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many

Immunology of Psoriatic Disease

Immunology of Psoriatic Disease
  • Author : Eva Reali,Nicolò Costantino Brembilla
  • Publisher : Frontiers Media SA
  • Release Date : 2019-07-31
  • ISBN : 9782889459186
GET THIS BOOKImmunology of Psoriatic Disease

Psoriasis is a chronically relapsing inflammatory skin disorder affecting about 2% of the worldwide population. The disease is associated with important systemic manifestations, including cardiovascular comorbidities and metabolic syndrome. In addition, about 30% of patients develop joint inflammation known as psoriatic arthritis (PsA). Our knowledge on the pathogenesis of psoriasis has dramatically expanded in the last decade, suggesting the existence (or co-existence) of both auto-immune and auto-inflammatory components. Skin lesions develop from a complex interplay between keratinocytes, vascular endothelium, dendritic cells, and