Translational Biology in Medicine

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  • Publisher : Elsevier
  • Release : 08 December 2014
  • ISBN : 9781908818652
  • Page : 228 pages
  • Rating : 4.5/5 from 103 voters

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The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine. Describes cellular and animal model systems used in translational research Discusses the use of blood, genetic and genomic biomarkers for disease Presents translational studies in aging, tissue repair and infectious disease biomedicine

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Translational Biology in Medicine

Translational Biology in Medicine
  • Author : M. Montano
  • Publisher : Elsevier
  • Release Date : 2014-12-08
  • ISBN : 9781908818652
GET THIS BOOKTranslational Biology in Medicine

The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods

Translational Medicine: Tools And Techniques

Translational Medicine: Tools And Techniques
  • Author : Aamir Shahzad
  • Publisher : Academic Press
  • Release Date : 2015-11-24
  • ISBN : 9780128034941
GET THIS BOOKTranslational Medicine: Tools And Techniques

Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. The book also addresses regulatory processes in USA, EU, Japan and China. By providing details

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
  • Author : Martin Wehling
  • Publisher : Academic Press
  • Release Date : 2021-07-15
  • ISBN : 9780323999625
GET THIS BOOKPrinciples of Translational Science in Medicine

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as

Translational Systems Biology

Translational Systems Biology
  • Author : Yoram Vodovotz,Gary An
  • Publisher : Elsevier
  • Release Date : 2014-10-08
  • ISBN : 9780123978905
GET THIS BOOKTranslational Systems Biology

Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money’s worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease
  • Author : Stephen Sonis,Alessandro Villa
  • Publisher : Academic Press
  • Release Date : 2019-09-14
  • ISBN : 9780128137635
GET THIS BOOKTranslational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine
  • Author : Qing Yan
  • Publisher : Academic Press
  • Release Date : 2017-04-18
  • ISBN : 9780128043882
GET THIS BOOKTranslational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics,

Cell Biology and Translational Medicine, Volume 12

Cell Biology and Translational Medicine, Volume 12
  • Author : Kursad Turksen
  • Publisher : Springer Nature
  • Release Date : 2021-07-20
  • ISBN : 9783030719333
GET THIS BOOKCell Biology and Translational Medicine, Volume 12

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as

Translational Control in Biology and Medicine

Translational Control in Biology and Medicine
  • Author : Michael Mathews,Nahum Sonenberg,John W. B. Hershey
  • Publisher : CSHL Press
  • Release Date : 2007
  • ISBN : 9780879697679
GET THIS BOOKTranslational Control in Biology and Medicine

Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.

Translational Research in Breast Cancer

Translational Research in Breast Cancer
  • Author : Erwei Song,Hai Hu
  • Publisher : Springer
  • Release Date : 2017-12-28
  • ISBN : 9789811060205
GET THIS BOOKTranslational Research in Breast Cancer

This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. In addition, major advances in cancer biology, immunology, genomics and metabolism have broken

Translational Biotechnology

Translational Biotechnology
  • Author : Yasha Hasija
  • Publisher : Academic Press
  • Release Date : 2021-01-17
  • ISBN : 9780128219737
GET THIS BOOKTranslational Biotechnology

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This

Cell Biology and Translational Medicine, Volume 3

Cell Biology and Translational Medicine, Volume 3
  • Author : Kursad Turksen
  • Publisher : Springer
  • Release Date : 2018-11-28
  • ISBN : 9783030041854
GET THIS BOOKCell Biology and Translational Medicine, Volume 3

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as

Translational Bioinformatics in Healthcare and Medicine

Translational Bioinformatics in Healthcare and Medicine
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-05-13
  • ISBN : 9780323898904
GET THIS BOOKTranslational Bioinformatics in Healthcare and Medicine

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining,

Translational Research in Breast Cancer

Translational Research in Breast Cancer
  • Author : Dong-Young Noh,Wonshik Han,Masakazu Toi
  • Publisher : Springer Nature
  • Release Date : 2021-05-13
  • ISBN : 9789813296206
GET THIS BOOKTranslational Research in Breast Cancer

This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in

Biomaterials in Translational Medicine

Biomaterials in Translational Medicine
  • Author : Lei Yang,Sarit Bhaduri,Thomas J. Webster
  • Publisher : Academic Press
  • Release Date : 2018-11-30
  • ISBN : 9780128134788
GET THIS BOOKBiomaterials in Translational Medicine

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : David B. Teplow
  • Publisher : Academic Press
  • Release Date : 2018-10-16
  • ISBN : 9780128162361
GET THIS BOOKProgress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science, Volume 159, provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series includes in-depth knowledge on molecular biological aspects of organismal physiology, along with insights on how this knowledge may be applied to understand and ameliorate human disease. New chapters in this release discuss timely topics, such as Targeting recently deorphanized GPR83 for the treatment of infection, stress, and