Translating Epigenetics to the Clinic

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  • Publisher : Academic Press
  • Release : 30 December 2016
  • ISBN : 9780128006122
  • Page : 324 pages
  • Rating : 4.5/5 from 103 voters

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Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole. Encompasses the latest innovations and tools being used to apply epigenetics in the lab and clinic Features extensive pedagogical updates aiming to improve the education of translational researchers in this field Offers a transdisciplinary approach to support cross-fertilization between different sub-specialties of medicine

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Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release Date : 2016-12-30
  • ISBN : 9780128006122
GET THIS BOOKTranslating Epigenetics to the Clinic

Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders

Molecular Biology of Cancer: Translation to the Clinic

Molecular Biology of Cancer: Translation to the Clinic
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • ISBN : 012385072X
GET THIS BOOKMolecular Biology of Cancer: Translation to the Clinic

Advances in molecular biology over the last several decades are being steadily applied to our understanding of the molecular biology of cancer, and these advances in knowledge are being translated into the clinical practice of oncology. This volume explores some of the most exciting recent advances in basic research on the molecular biology of cancer and how this knowledge is leading to advances in the diagnosis, treatment, and prevention of cancer. * This series provides a forum for discussion of new

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release Date : 2015-09-01
  • ISBN : 0128005483
GET THIS BOOKTranslating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic
  • Author : Jeffrey Laurence,Pedro Baptista,Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2015-11-18
  • ISBN : 9780128005521
GET THIS BOOKTranslating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent

Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics
  • Author : Gerda Egger,Paola Arimondo
  • Publisher : Academic Press
  • Release Date : 2015-11-19
  • ISBN : 9780128024928
GET THIS BOOKDrug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin

Epigenetics Territory and Cancer

Epigenetics Territory and Cancer
  • Author : Parvin Mehdipour
  • Publisher : Springer
  • Release Date : 2015-03-31
  • ISBN : 9401796386
GET THIS BOOKEpigenetics Territory and Cancer

This book explores epigenetic strategies, bridging fundamental cancer epigenetics, different paradigms in tumor genetics and translational understanding for both the clinic and improved lifestyles. The work provides target-based insights for treating different types of cancers and presents research on evolutionary epigenetics, introducing ‘Medical Epi- Anthropology’ and ‘Cancer Epi-Anthropology’. Translating multi-disciplinary research into therapeutic design is at the core of this book. Readers may explore how cancer management involves unmasking the involved networks and the interactive status of different genes to

Epigenetics in Precision Medicine

Epigenetics in Precision Medicine
  • Author : Jose Luis Garcia-Gimenez
  • Publisher : Elsevier
  • Release Date : 2021-11-22
  • ISBN : 9780323858052
GET THIS BOOKEpigenetics in Precision Medicine

In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease
  • Author : Stephen Sonis,Alessandro Villa
  • Publisher : Academic Press
  • Release Date : 2019-09-14
  • ISBN : 9780128137635
GET THIS BOOKTranslational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease

Epigenetic Cancer Therapy

Epigenetic Cancer Therapy
  • Author : Steven Gray
  • Publisher : Academic Press
  • Release Date : 2015-07-01
  • ISBN : 9780128002247
GET THIS BOOKEpigenetic Cancer Therapy

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).

Common Pediatric Diseases: an Updated Review

Common Pediatric Diseases: an Updated Review
  • Author : Nima Rezaei,Noosha Samieefar
  • Publisher : Bentham Science Publishers
  • Release Date : 2022-04-14
  • ISBN : 9789815039665
GET THIS BOOKCommon Pediatric Diseases: an Updated Review

Common Pediatric Diseases: An Updated Review informs the reader about common diseases in children that are encountered by pediatricians and family physicians. Each of the 14 chapters in the volume presents updated information for readers with the aim to give them a current perspective on the topic. This book is a handy and practical compendium for medical students and healthcare professionals involved in general practice and pediatric clinics. The text starts with a quick introduction to pediatric diseases, before progressing towards

AGO-Driven Non-Coding RNAs

AGO-Driven Non-Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release Date : 2019-01-20
  • ISBN : 9780128156704
GET THIS BOOKAGO-Driven Non-Coding RNAs

The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years,

Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology

Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
  • Author : Antonella Fioravanti,Francesco Dotta,Antonio Giordano,Luigi Pirtoli
  • Publisher : MDPI
  • Release Date : 2020-06-18
  • ISBN : 9783039363308
GET THIS BOOKCrosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology

MicroRNAs (miRNAs) are small noncoding RNAs that are 19–24 nucleotides in length, following maturation. Recent evidence has demonstrated their key role as post-transcriptional regulators of gene expression through the binding of specific sequences within target messenger RNA (mRNA). miRNAs are involved in the synthesis of a very large number of proteins, and it is speculated that they could regulate up to 30% of the human genome. They control virtually every cellular process and are essential for animal development, cell differentiation, and homeostasis.

DNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease
  • Author : Michel Neidhart
  • Publisher : Academic Press
  • Release Date : 2015-08-11
  • ISBN : 9780127999203
GET THIS BOOKDNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as

Genomic Applications in Pathology

Genomic Applications in Pathology
  • Author : George Jabboure Netto,Karen L. Kaul
  • Publisher : Springer
  • Release Date : 2018-12-10
  • ISBN : 9783319968308
GET THIS BOOKGenomic Applications in Pathology

​The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As

Cardiac Diseases

Cardiac Diseases
  • Author : David C. Gaze,Aleksandar Kibel
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-07-28
  • ISBN : 9781839681615
GET THIS BOOKCardiac Diseases

This is the latest book in a series of cardiovascular-related texts from IntechOpen Publishing. The present volume considers general aspects of cardiac disease and is divided into three distinct sections covering cardiac risk, cardiorenal pathology, and novel interventional surgical techniques. The chapters offer insight into the current state of the art with respect to the risks of developing cardiovascular diseases, maintenance of patent vascular access in patients with the cardiorenal syndrome, and a plethora of novel interventional technologies all aimed