Transgenerational Epigenetics

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  • Publisher : Elsevier
  • Release : 02 May 2014
  • ISBN : 9780124059221
  • Page : 412 pages
  • Rating : 4.5/5 from 103 voters

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Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research. Focused discussion of metabolic disorders, cardiovascular diseases and longevity, which appear most affected by reversible and heritable epigenetic processes Encompasses both foundational and clinical aspects including discussions of preventative in utero therapies Covers history, future outlook, disease management and current controversies

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Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Elsevier
  • Release Date : 2014-05-02
  • ISBN : 9780124059221
GET THIS BOOKTransgenerational Epigenetics

Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms

Environmental Epigenetics

Environmental Epigenetics
  • Author : L. Joseph Su,Tung-chin Chiang
  • Publisher : Springer
  • Release Date : 2015-05-18
  • ISBN : 9781447166788
GET THIS BOOKEnvironmental Epigenetics

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2019-08-15
  • ISBN : 0128163631
GET THIS BOOKTransgenerational Epigenetics

Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather reversible and heritable epigenetic processes. These processes may have selective or adverse effects on offspring persisting for multiple generations. Transgenerational Epigenetics, Second Edition offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with emphasis on human disease relevance, drug discovery, and next steps in clinical translation. Here, international experts discuss mechanisms of epigenetic inheritance, its expression in

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-05-18
  • ISBN : 9780128167335
GET THIS BOOKTransgenerational Epigenetics

Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the

Epigenetics in Psychiatry

Epigenetics in Psychiatry
  • Author : Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
  • Publisher : Academic Press
  • Release Date : 2021-08-16
  • ISBN : 9780128235782
GET THIS BOOKEpigenetics in Psychiatry

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent

The Maternal Imprint

The Maternal Imprint
  • Author : Sarah S. Richardson
  • Publisher : University of Chicago Press
  • Release Date : 2021-11-08
  • ISBN : 9780226807072
GET THIS BOOKThe Maternal Imprint

Leading gender and science scholar Sarah S. Richardson charts the untold history of the idea that a woman's health and behavior during pregnancy can have long-term effects on her descendants' health and welfare. The idea that a woman may leave a biological trace on her gestating offspring has long been a commonplace folk intuition and a matter of scientific intrigue, but the form of that idea has changed dramatically over time. Beginning with the advent of modern genetics at the

Environmental Epigenetics in Toxicology and Public Health

Environmental Epigenetics in Toxicology and Public Health
  • Author : Rebecca Fry
  • Publisher : Academic Press
  • Release Date : 2020-10-18
  • ISBN : 9780128199695
GET THIS BOOKEnvironmental Epigenetics in Toxicology and Public Health

Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
  • Author : Cheryl S Rosenfeld
  • Publisher : Academic Press
  • Release Date : 2015-10-10
  • ISBN : 9780128016725
GET THIS BOOKThe Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological

Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-09-12
  • ISBN : 9780128197547
GET THIS BOOKEpigenetics and Reproductive Health

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release Date : 2015-10-19
  • ISBN : 9780128004715
GET THIS BOOKEpigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2017-07-10
  • ISBN : 9780128054772
GET THIS BOOKHandbook of Epigenetics

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue

Lysenko’s Ghost

Lysenko’s Ghost
  • Author : Loren Graham
  • Publisher : Harvard University Press
  • Release Date : 2016-04-11
  • ISBN : 9780674969049
GET THIS BOOKLysenko’s Ghost

Lysenko became one of the most notorious figures in twentieth-century science after his genetic theories were discredited decades ago. Yet some scientists now claim that discoveries in epigenetics prove that he was right after all. Loren Graham reopens the case, to determine whether new developments in molecular biology validate Lysenko’s claims.

Epigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders
  • Author : Nagy Youssef
  • Publisher : Academic Press
  • Release Date : 2022-02-25
  • ISBN : 9780128230626
GET THIS BOOKEpigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders, Volume 31 in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA or gene expression following prolonged stress and/or trauma. Sections introduce both genetic and psychiatric foundations, including modes of epigenetic modification and gene expression that result from stress, as well as the medical knowledge required to understand stress related disorders and resilience. From here, chapters discuss epigenetic research techniques applied in recent studies, including epigenome-wide association studies (EWAS) of PTSD

Epigenetics

Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2014-08-12
  • ISBN : 9780128014721
GET THIS BOOKEpigenetics

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Epigenetics This book looks at Epigeneticsin the light of the newest scholarly discoveries and insights

Epigenetics of Exercise and Sports

Epigenetics of Exercise and Sports
  • Author : Stuart Raleigh
  • Publisher : Academic Press
  • Release Date : 2021-07-13
  • ISBN : 9780128209370
GET THIS BOOKEpigenetics of Exercise and Sports

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports