Toxicogenomics Based Cellular Models

Book Toxicogenomics Based Cellular Models Cover

Read or download book entitled Toxicogenomics Based Cellular Models written by Jos Kleinjans and published by Unknown in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Toxicogenomics Based Cellular Models book is available in the library.

  • Publisher : Unknown
  • Release : 29 January 2014
  • ISBN : 0123978629
  • Page : 362 pages
  • Rating : 4.5/5 from 103 voters

Download Toxicogenomics Based Cellular Models in PDF, Epub and Kindle

Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores 'omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing. Describes the state-of-the-art in developing toxicogenomics-based cellular models for chemical-induced carcinogenicity, immunotoxicity, developmental toxicity, neurotoxicity and reproduction toxicity Illustrates how to validate toxicogenomics-based alternative test models and provides an outlook to societal and economic implementation of these novel assays Includes an overview of current testing methods and risk assessment frameworks Provides a real-world assessment by articulating the current development and challenges in toxicogenomics while suggesting ways to move this field forward

GET THIS BOOK

Toxicogenomics-Based Cellular Models

Toxicogenomics-Based Cellular Models
  • Author : Jos Kleinjans
  • Publisher : Unknown
  • Release Date : 2014-01-29
  • ISBN : 0123978629
GET THIS BOOKToxicogenomics-Based Cellular Models

Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well

Toxicogenomics-Based Cellular Models

Toxicogenomics-Based Cellular Models
  • Author : Jos Kleinjans
  • Publisher : Academic Press
  • Release Date : 2014-01-02
  • ISBN : 9780123978714
GET THIS BOOKToxicogenomics-Based Cellular Models

Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well

Toxicogenomics in Predictive Carcinogenicity

Toxicogenomics in Predictive Carcinogenicity
  • Author : Michael D. Waters,Russell S. Thomas
  • Publisher : Royal Society of Chemistry
  • Release Date : 2016-06-10
  • ISBN : 9781782621621
GET THIS BOOKToxicogenomics in Predictive Carcinogenicity

Describes toxicogenomics methods in predictive carcinogenicity testing and cancer risk assessment. Addresses the use of stem cells and bioinformatics in toxicogenomics. For postgraduates, academics and industrialists.

Information Resources in Toxicology

Information Resources in Toxicology
  • Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
  • Publisher : Academic Press
  • Release Date : 2020-05-16
  • ISBN : 9780128137253
GET THIS BOOKInformation Resources in Toxicology

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world

Big Data in Predictive Toxicology

Big Data in Predictive Toxicology
  • Author : Andrea-Nicole Richarz,Daniel Neagu
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-12-10
  • ISBN : 9781839160820
GET THIS BOOKBig Data in Predictive Toxicology

The rate at which toxicological data is generated is continually becoming more rapid and the volume of data generated is growing dramatically. This is due in part to advances in software solutions and cheminformatics approaches which increase the availability of open data from chemical, biological and toxicological and high throughput screening resources. However, the amplified pace and capacity of data generation achieved by these novel techniques presents challenges for organising and analysing data output. Big Data in Predictive Toxicology discusses

Integrative Toxicogenomics: Analytical Strategies to Amalgamate Exposure Effects with Genomic Sciences

Integrative Toxicogenomics: Analytical Strategies to Amalgamate Exposure Effects with Genomic Sciences
  • Author : Pierre R. Bushel,Weida Tong
  • Publisher : Frontiers Media SA
  • Release Date : 2019-04-09
  • ISBN : 9782889457663
GET THIS BOOKIntegrative Toxicogenomics: Analytical Strategies to Amalgamate Exposure Effects with Genomic Sciences

Toxicogenomics combines the use of toxicology and genomic sciences to elucidate chemical, toxic and environmental stressor effects on biological systems. Integrative toxicogenomics requires innovation in bioinformatics, statistics and systems toxicology and typically a combination of the utility of two of more of these disciplines to better understand molecular mechanisms involved in toxic responses. This Frontiers in Toxicogenomics Research Topic eBook focuses on integrative toxicogenomics more so at the late stage (analyzing each data set separately and then merging the results )

Pharmacokinetics and Toxicokinetic Considerations - Vol II

Pharmacokinetics and Toxicokinetic Considerations - Vol II
  • Author : Rakesh Kumar Tekade
  • Publisher : Academic Press
  • Release Date : 2022-02-17
  • ISBN : 9780323913164
GET THIS BOOKPharmacokinetics and Toxicokinetic Considerations - Vol II

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their

Advances in Molecular Toxicology

Advances in Molecular Toxicology
  • Author : James C. Fishbein,Jacqueline M. Heilman
  • Publisher : Academic Press
  • Release Date : 2018-09-21
  • ISBN : 9780444641984
GET THIS BOOKAdvances in Molecular Toxicology

Advances in Molecular Toxicology, Volume Twelve, features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The work not only documents these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The

Translating Diverse Environmental Data into Reliable Information

Translating Diverse Environmental Data into Reliable Information
  • Author : Daniel Vallero
  • Publisher : Academic Press
  • Release Date : 2017-09-15
  • ISBN : 9780128124475
GET THIS BOOKTranslating Diverse Environmental Data into Reliable Information

Translating Diverse Environmental Data into Reliable Information: How to Coordinate Evidence from Different Sources is a resource for building environmental knowledge, particularly in the era of Big Data. Environmental scientists, engineers, educators and students will find it essential to determine data needs, assess their quality, and efficiently manage their findings. Decision makers can explore new open access databases and tools, especially portals and dashboards. The book demonstrates how environmental knowledgebases are and can be built to meet the needs of

Risk Assessment for Human Metal Exposures

Risk Assessment for Human Metal Exposures
  • Author : Gunnar F. Nordberg,Bruce A. Fowler
  • Publisher : Academic Press
  • Release Date : 2018-08-21
  • ISBN : 9780128042687
GET THIS BOOKRisk Assessment for Human Metal Exposures

Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA –TKTD can be used. In addition, it presents tactics on how information generated by such methods

Toxicoepigenetics

Toxicoepigenetics
  • Author : Shaun D. McCullough,Dana Dolinoy
  • Publisher : Academic Press
  • Release Date : 2018-11-02
  • ISBN : 9780128124345
GET THIS BOOKToxicoepigenetics

Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment
  • Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology
  • Publisher : National Academies Press
  • Release Date : 2007-11-19
  • ISBN : 0309178894
GET THIS BOOKApplications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort

Comprehensive Toxicology

Comprehensive Toxicology
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2010-06-01
  • ISBN : 9780080468846
GET THIS BOOKComprehensive Toxicology

An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides

The History of Alternative Test Methods in Toxicology

The History of Alternative Test Methods in Toxicology
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-10-20
  • ISBN : 9780128136980
GET THIS BOOKThe History of Alternative Test Methods in Toxicology

The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and

Toxicology and Risk Assessment

Toxicology and Risk Assessment
  • Author : Helmut Greim,Robert Snyder
  • Publisher : John Wiley & Sons
  • Release Date : 2018-08-10
  • ISBN : 9781119135920
GET THIS BOOKToxicology and Risk Assessment

Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise