The Protective Arm of the Renin Angiotensin System RAS

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  • Publisher : Academic Press
  • Release : 18 April 2015
  • ISBN : 9780128014851
  • Page : 316 pages
  • Rating : 4.5/5 from 103 voters

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The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

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The Protective Arm of the Renin Angiotensin System (RAS)

The Protective Arm of the Renin Angiotensin System (RAS)
  • Author : Thomas Unger,U. Muscha Steckelings,Robson Augusto Souza dos Santos
  • Publisher : Academic Press
  • Release Date : 2015-04-18
  • ISBN : 9780128014851
GET THIS BOOKThe Protective Arm of the Renin Angiotensin System (RAS)

The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin

The Protective Arm of the Renin Angiotensin System (Ras)

The Protective Arm of the Renin Angiotensin System (Ras)
  • Author : Thomas Unger,U. Muscha Steckelings,Robson Augusto Souza Dos Santos
  • Publisher : Academic Press
  • Release Date : 2015-04-20
  • ISBN : 0128013648
GET THIS BOOKThe Protective Arm of the Renin Angiotensin System (Ras)

The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin-angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2

Selected Chapters from the Renin-Angiotensin System

Selected Chapters from the Renin-Angiotensin System
  • Author : Aleksandar Kibel
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-08-19
  • ISBN : 9781789854213
GET THIS BOOKSelected Chapters from the Renin-Angiotensin System

Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of

Angiotensin-(1-7)

Angiotensin-(1-7)
  • Author : Robson Augusto Souza Santos
  • Publisher : Springer Nature
  • Release Date : 2019-08-21
  • ISBN : 9783030226961
GET THIS BOOKAngiotensin-(1-7)

This is the first book addressing in full the most important aspects of the angiotensin-(1-7), the key peptide of the protective axis and the main component in the new modulatory concept of the renin-angiotensin system. It features a detailed review of angiotensin-(1-7) and its receptor Mas, comprising the historical background, enzymatic pathways for generation, functions, integrative aspects of its protective profile, and its therapeutic potential. It also encompasses a comprehensive presentation of current knowledge about its widespread biological

The Renin-Angiotensin System

The Renin-Angiotensin System
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  • Publisher : Unknown
  • Release Date : 2003-08-01
  • ISBN : 4896005848
GET THIS BOOKThe Renin-Angiotensin System

The Renin Angiotensin System in Cardiovascular Disease

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  • Publisher : Springer Nature
  • Release Date : 2023-02-02
  • ISBN : 9783031149528
GET THIS BOOKThe Renin Angiotensin System in Cardiovascular Disease

This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in

Aldosterone-Mineralocorticoid Receptor

Aldosterone-Mineralocorticoid Receptor
  • Author : Brian Harvey,Frederic Jaisser
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-09-25
  • ISBN : 9781839621987
GET THIS BOOKAldosterone-Mineralocorticoid Receptor

This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16

The Renin-Angiotensin-Aldosterone System

The Renin-Angiotensin-Aldosterone System
  • Author : Sean E. Thatcher
  • Publisher : Humana Press
  • Release Date : 2017-05-13
  • ISBN : 1493970283
GET THIS BOOKThe Renin-Angiotensin-Aldosterone System

This volume discusses protocols that aid in measuring different components in the renin-angiotensin-aldosterone system (RAAS). The book also looks at the methods used to assess angiotensin peptides and discerning the influence of RAAS components on different mammalian diseases. The chapters cover topics such as the use of fluorescent substrate to measure ACE2 activity in the mouse abdominal aorta, blood pressure monitoring using the radio telemetry method, and the analysis of angiotensin metabolism in the kidney using mass spectrometry. Written in

The Role of the Renin-Angiotensin System in the Central Nervous System

The Role of the Renin-Angiotensin System in the Central Nervous System
  • Author : Natalia P. Rocha,Antonio Lucio Teixeira,Ana Cristina Simões E. Silva
  • Publisher : Frontiers Media SA
  • Release Date : 2021-10-01
  • ISBN : 9782889713455
GET THIS BOOKThe Role of the Renin-Angiotensin System in the Central Nervous System

Manual of Hypertension of the European Society of Hypertension, Third Edition

Manual of Hypertension of the European Society of Hypertension, Third Edition
  • Author : Giuseppe Mancia,Guido Grassi,Konstantinos Tsioufis,Anna Dominiczak,Enrico Agabiti Rosei
  • Publisher : CRC Press
  • Release Date : 2019-06-06
  • ISBN : 9780429581441
GET THIS BOOKManual of Hypertension of the European Society of Hypertension, Third Edition

The Manual of Hypertension of the European Society of Hypertension reflects emerging concepts that have the potential to impact diagnostic and therapeutic approaches to hypertension. Updating all material, this new edition also delves into a number of areas that have received heightened interest in recent years or have become a matter of debate due to the controversial interpretation of the available data. FEATURES Reflects emerging concepts impacting diagnostic and therapeutic approaches Explores background, history, epidemiology, and risk factors Describes pharmacological,

Textbook of Nephro-Endocrinology

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  • Author : Ajay K. Singh,Gordon H. Williams
  • Publisher : Academic Press
  • Release Date : 2009-01-12
  • ISBN : 0080920462
GET THIS BOOKTextbook of Nephro-Endocrinology

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a

Receptor Endocytosis and Signalling in Health and Disease - Part A

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  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2023-01-20
  • ISBN : 9780443191862
GET THIS BOOKReceptor Endocytosis and Signalling in Health and Disease - Part A

Receptor Endocytosis and Signalling in Health and Disease, Volume 194 in the Progress in Molecular Biology and Translational Science, highlights new advances in the field. Chapters in this release include An overview on receptor endocytosis and signaling, Signaling molecules: Importance in health and disease conditions, Emerging tools for studying of receptor endocytosis and signaling, Endocytosis of EGFR: Signalling in cancer, Endocytosis of AT1 and AT2 receptors: Signalling in the kidney, Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants,

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  • Publisher : Springer Nature
  • Release Date : 2021-07-02
  • ISBN : 9789813368279
GET THIS BOOKTargeting Cellular Signalling Pathways in Lung Diseases

The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and

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  • Publisher : Frontiers Media SA
  • Release Date : 2022-10-13
  • ISBN : 9782832502310
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From Hypertension to Heart Failure

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  • Author : Michael Böhm,John H. Laragh,Manfred Zehender
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9783642603006
GET THIS BOOKFrom Hypertension to Heart Failure

Arterial hypertension, coronary heart disease and heart fail ure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become in creasingly clear that they are closely and causally interrelated and that their relationship can have a significant bearing on prognosis. Epidemiological studies have shown that arterial hypertension is one of the most important risk factors for de veloping heart failure. Only one in four patients with hyper tension is adequately managed, and