The Paracellular Channel

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  • Publisher : Academic Press
  • Release : 08 June 2018
  • ISBN : 9780128146361
  • Page : 248 pages
  • Rating : 4.5/5 from 103 voters

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The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization. Offers integrated coverage of all key aspects of the paracellular channel, an understudied field that may hold key insights into some of the most mysterious aspects of physiology Targets different levels of expertise, spanning from graduate students, interns and clinical fellows, to seasoned researchers that study functions, regulation and dysfunctions of different tissue barriers Provides a cohesive and unifying picture that describes the critical functions of paracellular channels (tight junctions) in different tissues

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The Paracellular Channel

The Paracellular Channel
  • Author : Jianghui Hou
  • Publisher : Academic Press
  • Release Date : 2018-06-08
  • ISBN : 9780128146361
GET THIS BOOKThe Paracellular Channel

The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure

A Laboratory Guide to the Tight Junction

A Laboratory Guide to the Tight Junction
  • Author : Jianghui Hou
  • Publisher : Academic Press
  • Release Date : 2020-04-24
  • ISBN : 9780128226438
GET THIS BOOKA Laboratory Guide to the Tight Junction

A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches

Model for the Architecture of Claudin-Based Paracellular Ion Channels Through Tight Junctions

Model for the Architecture of Claudin-Based Paracellular Ion Channels Through Tight Junctions
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2015
  • ISBN : OCLC:1052007766
GET THIS BOOKModel for the Architecture of Claudin-Based Paracellular Ion Channels Through Tight Junctions

Calcium Entry Channels in Non-Excitable Cells

Calcium Entry Channels in Non-Excitable Cells
  • Author : Juliusz Ashot Kozak,James W. Putney, Jr.
  • Publisher : CRC Press
  • Release Date : 2017-07-14
  • ISBN : 9781498752732
GET THIS BOOKCalcium Entry Channels in Non-Excitable Cells

Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • ISBN : 0815332181
GET THIS BOOKMolecular Biology of the Cell

Barriers and Channels Formed by Tight Junction Proteins I

Barriers and Channels Formed by Tight Junction Proteins I
  • Author : Michael Fromm,Jörg-Dieter Schulzke
  • Publisher : Wiley-Blackwell
  • Release Date : 2012-06-19
  • ISBN : 1573318736
GET THIS BOOKBarriers and Channels Formed by Tight Junction Proteins I

Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in

Biological Barriers to Protein Delivery

Biological Barriers to Protein Delivery
  • Author : Kenneth L. Audus,Thomas J. Raub,T. L. Raub
  • Publisher : Springer Science & Business Media
  • Release Date : 1993
  • ISBN : 0306443686
GET THIS BOOKBiological Barriers to Protein Delivery

A current and critical review of information regarding peptide and protein transport and metabolism as it relates to delivery of endogenous (physiological ligands) and recombinant proteins to mammalian organs, tissues, and cells. Each chapter emphasizes mechanisms of transport including quantitative evidence and structure/function (cause/effect) relationships. The volume is intended to be a comprehensive, state-of-the-art treatise for use by academic and industrial scientists who either are just beginning or are entrenched in the field of protein drug delivery. Annotation

Introduction to Cellular Biophysics, Volume 2

Introduction to Cellular Biophysics, Volume 2
  • Author : Armin Kargol
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2019-12-13
  • ISBN : 9781643277561
GET THIS BOOKIntroduction to Cellular Biophysics, Volume 2

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are

Cell-Cell Channels

Cell-Cell Channels
  • Author : František Baluška,Dieter Volkmann,Peter W. Barlow
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-08-10
  • ISBN : 9780387469577
GET THIS BOOKCell-Cell Channels

he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to

The Cerebral Circulation

The Cerebral Circulation
  • Author : Marilyn J. Cipolla
  • Publisher : Biota Publishing
  • Release Date : 2016-07-28
  • ISBN : 9781615047239
GET THIS BOOKThe Cerebral Circulation

This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike

Barriers and Channels Formed by Tight Junction Proteins

Barriers and Channels Formed by Tight Junction Proteins
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2011
  • ISBN : OCLC:1075781079
GET THIS BOOKBarriers and Channels Formed by Tight Junction Proteins

Current Frontiers and Perspectives in Cell Biology

Current Frontiers and Perspectives in Cell Biology
  • Author : Stevo Najman
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-04-25
  • ISBN : 9789535105442
GET THIS BOOKCurrent Frontiers and Perspectives in Cell Biology

A numerous internationally renowned authors in the pages of this book present the views of the fields of cell biology and their own research results or review of current knowledge. Chapters are divided into five sections that are dedicated to cell structures and functions, genetic material, regulatory mechanisms, cellular biomedicine and new methods in cell biology. Multidisciplinary and often quite versatile approach by many authors have imposed restrictions of this classification, so it is certain that many chapters could belong

International Review of Cytology

International Review of Cytology
  • Author : Kwang W. Jeon
  • Publisher : Elsevier
  • Release Date : 2006-02-20
  • ISBN : 008047862X
GET THIS BOOKInternational Review of Cytology

International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address new insights into fatty acid modulation of pancreatic beta cell function; drosophila RNA binding proteins; plasticity of pelvic autonomic ganglia and urogenital innervation; vomeronasal vs. olifactory epithelium: cellular basis for human vomeronasal perception; and tight junctions.

Drug Delivery Systems

Drug Delivery Systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-10-23
  • ISBN : 9780128145081
GET THIS BOOKDrug Delivery Systems

Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery

Brenner and Rector's The Kidney E-Book

Brenner and Rector's The Kidney E-Book
  • Author : Alan S. L. Yu,Glenn M. Chertow,Valerie Luyckx,Philip A. Marsden,Karl Skorecki,Maarten W. Taal
  • Publisher : Elsevier Health Sciences
  • Release Date : 2015-10-25
  • ISBN : 9780323262590
GET THIS BOOKBrenner and Rector's The Kidney E-Book

Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of