The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

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  • Publisher : Academic Press
  • Release : 08 April 2015
  • ISBN : 9780128033227
  • Page : 390 pages
  • Rating : 4.5/5 from 103 voters

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Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation–related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers

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The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae
  • Author : Rainer Straub
  • Publisher : Academic Press
  • Release Date : 2015-04-08
  • ISBN : 9780128033227
GET THIS BOOKThe Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting – cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae
  • Author : Rainer Straub, MD
  • Publisher : Academic Press
  • Release Date : 2015-04-21
  • ISBN : 0128033215
GET THIS BOOKThe Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting - cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of

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  • ISBN : 9780128113899
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  • ISBN : 9788132226802
GET THIS BOOKBiology of C Reactive Protein in Health and Disease

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (

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GET THIS BOOKRheumatology E-Book

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GET THIS BOOKWired to Eat

NEW YORK TIMES BESTSELLER • Reset your metabolism for lasting fat loss in one month and discover the carbs that are right for you. The surprising truth is that we are genetically wired to eat more and move less, the exact opposite of the advice we are often given. Now there is a more customized weight loss solution that works with your body, a solution based not on arbitrary restriction of foods but on what works for YOU. Developed by former

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  • Publisher : Mayank Dabral
  • Release Date : 2022-02-01
  • ISBN : 0987654321XXX
GET THIS BOOKPractical neuroendocrine pathophysiology: a viewpoint

This book provides an alternative viewpoint towards classification of systemic pathophysiology. There is a recurring theme, i.e. Embryonic origin and the neuroendocrine basis of disease classification. Pathologies have been classified into inflammatory and degenerative, alpha and beta adrenergic inflammation, pre and postganglionic congenital defect. Hopefully it will complement the current classification of disease and yield a more complete picture of the disease to the reader. The first three chapters form the crux of the book, followed by systemwise examples

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  • Publisher : Butterworth-Heinemann
  • Release Date : 2014-04-03
  • ISBN : 9781483164366
GET THIS BOOKThe Eye in Systemic Disease

The Eye in Systemic Disease, Second Edition presents an overview of the relationship of the eye and medicine. The book details the systemic aspects of diseases. The topics discussed include various eye conditions such as conjunctivitis, episcleritis, keratitis, keratoconjunctivitis sicca, and cataract. Endocrine, circulatory, rheumatological, neurological, pulmonary, and blood disorders are covered as well. Physicians and students of medicine and pathology will find the book very useful.

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  • Publisher : Quintessenz Verlag
  • Release Date : 2021-04-19
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GET THIS BOOKPeriodontitis and Systemic Diseases

The association between periodontitis and systemic diseases has become a hot topic in recent years. This comprehensive book reviews the clinical evidence and biological plausibility of the many systemic diseases that have been linked to periodontitis. Edited by Dr Josefine Hirschfeld and Prof Iain L.C. Chapple, experts in each field discuss the mechanisms at work, citing the available key literature and clearly summarising current knowledge and understanding of the associations between periodontitis and diabetes mellitus, cardiovascular diseases, chronic kidney

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GET THIS BOOKNeurologic Aspects of Systemic Disease

Systemic disease involves several parts of the body or the complete system. This comprehensive reference focuses on the specific neurologic aspects of systemic disease. Part 3 includes coverage of oncologic disorders, organ transplantation, infectious diseases, tropical neurology, pregnancy, neuroanesthesia and other diseases and disorders. Each chapter provides a complete introduction to the neurologic aspect and provides the best known diagnostic and treatment practices. The collection will be a valuable and trusted resource for clinical neurologists, research neurologists and neuroscientists and general

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GET THIS BOOKThe Impact of Nutrition and Statins on Cardiovascular Diseases

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