The Organic Chemistry of Drug Design and Drug Action

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  • Publisher : Elsevier
  • Release : 02 December 2012
  • ISBN : 9780080513379
  • Page : 617 pages
  • Rating : 4.5/5 from 103 voters

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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

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The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Elsevier
  • Release Date : 2012-12-02
  • ISBN : 9780080513379
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Elsevier
  • Release Date : 2012-12-02
  • ISBN : 9780080571232
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

This is a new approach to the teaching of medicinal chemistry. The knowledge of the physical organic chemical basis of drug design and drug action allows the reader to extrapolate to the many related classes of drugs described in standard medicinal chemistry texts. Students gain a solid foundation to base future research endeavors upon: drugs not yet developed are thus covered! n Emphasizes the use of the principles of physical organic chemistry as a basis for drug design n Discusses

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Academic Press
  • Release Date : 2004-01-12
  • ISBN : 0126437327
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

Standard medicinal texts are organized by classes of drugs with an emphasis on descriptions of their pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that rationalized drug action and allows the reader to extrapolate to many related classed of drug molecules.

Molecules and Medicine

Molecules and Medicine
  • Author : E. J. Corey,Barbara Czakó,László Kürti
  • Publisher : John Wiley & Sons
  • Release Date : 2012-02-28
  • ISBN : 9781118361733
GET THIS BOOKMolecules and Medicine

Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Chemistry and Molecular Aspects of Drug Design and Action

Chemistry and Molecular Aspects of Drug Design and Action
  • Author : E. A. Rekka,P. N. Kourounakis
  • Publisher : CRC Press
  • Release Date : 2008-04-28
  • ISBN : 9781420008272
GET THIS BOOKChemistry and Molecular Aspects of Drug Design and Action

An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to deve

The Ups and Downs in Drug Design

The Ups and Downs in Drug Design
  • Author : Victor E. Marquez
  • Publisher : CRC Press
  • Release Date : 2021-11-16
  • ISBN : 9781000462944
GET THIS BOOKThe Ups and Downs in Drug Design

The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry highlights the necessity for an integrative approach in medicinal chemistry and chemical biology. As medicinal chemistry is not a monolithic science, it is important to emphasize the other various disciplines that are required for successful drug design. This book presents the author’s own personal experience in this field and describes the "ups" and "downs" that come with drug discovery. It is an excellent companion text for graduate and

Heterocyclic Chemistry in Drug Discovery

Heterocyclic Chemistry in Drug Discovery
  • Author : Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release Date : 2013-04-26
  • ISBN : 9781118354438
GET THIS BOOKHeterocyclic Chemistry in Drug Discovery

Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman,Mark W. Holladay
  • Publisher : Academic Press
  • Release Date : 2014-03-29
  • ISBN : 9780123820310
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action
  • Author : Richard B. Silverman
  • Publisher : Academic Press
  • Release Date : 2005-01-19
  • ISBN : 0126437335
GET THIS BOOKThe Organic Chemistry of Drug Design and Drug Action

This CD-ROM edition of Silverman's Organic Chemisry of Drug Design and Drug Action, Second Edition reflects the significant changes in the drug industry in recent years, using an accessible interactive approach. This CD-ROM integrates the author's own PowerPoint slides, indexed and linked to the book pages in PDF format. The three-part structure includes an all-electronic text with full-text search capabilites and nearly 800 powerpoint slides. This is a unique and powerful combination of electronic study guide and full book pages. Users

An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry
  • Author : Graham L. Patrick
  • Publisher : Oxford University Press
  • Release Date : 2013-01-10
  • ISBN : 9780199697397
GET THIS BOOKAn Introduction to Medicinal Chemistry

This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.

Basic Concepts in Medicinal Chemistry

Basic Concepts in Medicinal Chemistry
  • Author : Marc Harrold,Robin Zavod
  • Publisher : ASHP
  • Release Date : 2013-01-18
  • ISBN : 9781585283644
GET THIS BOOKBasic Concepts in Medicinal Chemistry

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and

An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry
  • Author : Graham L. Patrick
  • Publisher : Oxford University Press, USA
  • Release Date : 2001
  • ISBN : 0198505337
GET THIS BOOKAn Introduction to Medicinal Chemistry

NEW TO THIS EDITION Updated throughout with the latest descoveries Five new chapters covering * the molecular structure of receptors and the mechanisms of signal transduction *combinatorial synthesis * the role of computers in drug design * adrenergics * drug discovery and drug development

Textbook of Drug Design and Discovery, Third Edition

Textbook of Drug Design and Discovery, Third Edition
  • Author : Tommy Liljefors,Povl Krogsgaard-Larsen,Ulf Madsen
  • Publisher : CRC Press
  • Release Date : 2002-07-25
  • ISBN : 0415282888
GET THIS BOOKTextbook of Drug Design and Discovery, Third Edition

Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for

The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry
  • Author : Camille Georges Wermuth,David Aldous,Pierre Raboisson,Didier Rognan
  • Publisher : Elsevier
  • Release Date : 2015-07-01
  • ISBN : 9780124172135
GET THIS BOOKThe Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to

Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development
  • Author : Benjamin E. Blass
  • Publisher : Academic Press
  • Release Date : 2021-03-30
  • ISBN : 9780128172155
GET THIS BOOKBasic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and