The Molecular and Clinical Pathology of Neurodegenerative Disease

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Read or download book entitled The Molecular and Clinical Pathology of Neurodegenerative Disease written by Patrick A. Lewis and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that The Molecular and Clinical Pathology of Neurodegenerative Disease book is available in the library.

  • Publisher : Academic Press
  • Release : 16 November 2018
  • ISBN : 9780128110706
  • Page : 274 pages
  • Rating : 4.5/5 from 103 voters

Download The Molecular and Clinical Pathology of Neurodegenerative Disease in PDF, Epub and Kindle

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration. Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis Highlights the state-of-the-art treatment options for each disorder Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models

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The Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease
  • Author : Patrick A. Lewis,Jennifer E. Spillane
  • Publisher : Academic Press
  • Release Date : 2018-11-16
  • ISBN : 9780128110706
GET THIS BOOKThe Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a

Neurodegeneration

Neurodegeneration
  • Author : Dennis Dickson,Roy O. Weller
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-09
  • ISBN : 9781444341232
GET THIS BOOKNeurodegeneration

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within

The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases
  • Author : Michael S. Wolfe
  • Publisher : Academic Press
  • Release Date : 2018-03-29
  • ISBN : 9780128113059
GET THIS BOOKThe Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative

Neuropathology of Neurodegenerative Diseases Book and Online

Neuropathology of Neurodegenerative Diseases Book and Online
  • Author : Gabor G. Kovacs
  • Publisher : Cambridge University Press
  • Release Date : 2014-12-04
  • ISBN : 9781107442429
GET THIS BOOKNeuropathology of Neurodegenerative Diseases Book and Online

This heavily illustrated, must-have practical guide aids medical specialists and trainees in the diagnosis of neurodegenerative diseases. Includes diagnostic algorithms.

Molecular Mechanisms of Neurodegenerative Diseases

Molecular Mechanisms of Neurodegenerative Diseases
  • Author : Marie-Francoise Chesselet
  • Publisher : Springer Science & Business Media
  • Release Date : 2000-10-19
  • ISBN : 9781592590063
GET THIS BOOKMolecular Mechanisms of Neurodegenerative Diseases

With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from

Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases

Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases
  • Author : Diana Fernandes Lázaro,Tiago F. Outeiro,Arianna Bellucci,Patrik Brundin
  • Publisher : Frontiers Media SA
  • Release Date : 2020-02-20
  • ISBN : 9782889635078
GET THIS BOOKProtein Misfolding and Spreading Pathology in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases
  • Author : Anil Gupta
  • Publisher : Academic Press
  • Release Date : 2021-12-17
  • ISBN : 9780128204436
GET THIS BOOKHuman Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. An important focus

TDP-43 and Neurodegeneration

TDP-43 and Neurodegeneration
  • Author : Vijay Kumar,Manoj Kumar Jaiswal
  • Publisher : Academic Press
  • Release Date : 2021-10-23
  • ISBN : 9780128204405
GET THIS BOOKTDP-43 and Neurodegeneration

Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells

Adenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases
  • Author : David Blum,Luisa V. Lopes
  • Publisher : Academic Press
  • Release Date : 2017-03-10
  • ISBN : 9780128037454
GET THIS BOOKAdenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal

Tau Pathology in Neurological Disorders

Tau Pathology in Neurological Disorders
  • Author : Sonia Do Carmo,A. Claudio Cuello,Maria Grazia Spillantini
  • Publisher : Frontiers Media SA
  • Release Date : 2021-11-12
  • ISBN : 9782889716258
GET THIS BOOKTau Pathology in Neurological Disorders

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Philip Beart,Michael Robinson,Marcus Rattray,Nicholas J. Maragakis
  • Publisher : Springer
  • Release Date : 2017-07-03
  • ISBN : 9783319571935
GET THIS BOOKNeurodegenerative Diseases

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such

CBD Oil for Neurodegenerative Disease

CBD Oil for Neurodegenerative Disease
  • Author : Desmond Cole
  • Publisher : Unknown
  • Release Date : 2019-06-17
  • ISBN : 1074420535
GET THIS BOOKCBD Oil for Neurodegenerative Disease

Neurodegenerative diseases are a major cause of progressive clinical disability causing impaired quality of life with consequences not only for the patient, but also their carer and the state. Global demographics dictate that age-related disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (motor neuron disease) will increase in incidence and prevalence and inevitably present a significant economic challenge to both established and emerging economies [1,2]. There are also many other disorders that fall under the umbrella of neurodegenerative

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
  • Author : Debra G.B. Leonard
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-25
  • ISBN : 9780387332277
GET THIS BOOKMolecular Pathology in Clinical Practice

This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage,

Molecular Pathology of Alzheimer's Disease

Molecular Pathology of Alzheimer's Disease
  • Author : Rudy Castellani,George Perry
  • Publisher : Biota Publishing
  • Release Date : 2013-10-31
  • ISBN : 9781615047413
GET THIS BOOKMolecular Pathology of Alzheimer's Disease

Alzheimer’s Disease is characterized pathologically by two principal hallmark lesions: the senile plaque and the neurofibrillary tangle. Since the identification of each over 100 years ago, the major protein components have been elucidated. This has led in turn to the elaboration of metabolic cascades involving amyloid-β production in the case of the senile plaque, and phosphorylated-tau protein in the case of the neurofibrillary tangle. The pathogenesis and histogenesis of each have been the source of extensive investigation and some controversy

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Nagehan Ersoy Tunalı
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-01-20
  • ISBN : 9781838801496
GET THIS BOOKNeurodegenerative Diseases

Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical