The Epigenome and Developmental Origins of Health and Disease

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  • Publisher : Academic Press
  • Release : 10 October 2015
  • ISBN : 9780128016725
  • Page : 560 pages
  • Rating : 4.5/5 from 103 voters

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The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field

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The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
  • Author : Cheryl S Rosenfeld
  • Publisher : Academic Press
  • Release Date : 2015-10-10
  • ISBN : 9780128016725
GET THIS BOOKThe Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological

Developmental Origins of Health and Disease

Developmental Origins of Health and Disease
  • Author : Peter Gluckman,Mark Hanson
  • Publisher : Cambridge University Press
  • Release Date : 2006-04-20
  • ISBN : 0521847435
GET THIS BOOKDevelopmental Origins of Health and Disease

This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these

Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease (DOHaD)
  • Author : Takeo Kubota,Hideoki Fukuoka
  • Publisher : Springer
  • Release Date : 2018-06-28
  • ISBN : 9789811055263
GET THIS BOOKDevelopmental Origins of Health and Disease (DOHaD)

This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early

Environmental Epigenetics

Environmental Epigenetics
  • Author : L. Joseph Su,Tung-chin Chiang
  • Publisher : Springer
  • Release Date : 2015-05-18
  • ISBN : 9781447166788
GET THIS BOOKEnvironmental Epigenetics

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended

Epigenetic Epidemiology

Epigenetic Epidemiology
  • Author : Karin B. Michels
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-02
  • ISBN : 9789400724952
GET THIS BOOKEpigenetic Epidemiology

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the

Epigenetics

Epigenetics
  • Author : Joel D. Wallach,Ma Lan,Gerhard N. Schrauzer
  • Publisher : SelectBooks, Inc.
  • Release Date : 2014-05
  • ISBN : 9781590792551
GET THIS BOOKEpigenetics

WHAT IS EPIGENETICS? Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA sequence. Epigenetics: The Death of the Genetic Theory of Disease Transmission is the result of decades of research and its findings that could be as critical to our understanding of human health as Pasteur’s research in bacteriology. Dr. Joel “Doc” Wallach has dedicated his life work to identifying connections between certain nutritional deficiencies and

Handbook of Nutrition, Diet, and Epigenetics

Handbook of Nutrition, Diet, and Epigenetics
  • Author : Vinood Patel,Victor Preedy
  • Publisher : Springer
  • Release Date : 2018-12-24
  • ISBN : 3319555294
GET THIS BOOKHandbook of Nutrition, Diet, and Epigenetics

This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode

The Routledge Handbook of Anthropology and Reproduction

The Routledge Handbook of Anthropology and Reproduction
  • Author : Sallie Han,Cecília Tomori
  • Publisher : Routledge
  • Release Date : 2021-11-09
  • ISBN : 9781000455984
GET THIS BOOKThe Routledge Handbook of Anthropology and Reproduction

The Routledge Handbook of Anthropology and Reproduction is a comprehensive overview of the topics, approaches, and trajectories in the anthropological study of human reproduction. The book brings together work from across the discipline of anthropology, with contributions by established and emerging scholars in archaeological, biological, linguistic, and sociocultural anthropology. Across these areas of research, consideration is given to the contexts, conditions, and contingencies that mark and shape the experiences of reproduction as always gendered, classed, and racialized. Over 39 chapters, a

Pre-emptive Medicine: Public Health Aspects of Developmental Origins of Health and Disease

Pre-emptive Medicine: Public Health Aspects of Developmental Origins of Health and Disease
  • Author : Fumihiro Sata,Hideoki Fukuoka,Mark Hanson
  • Publisher : Springer
  • Release Date : 2018-12-11
  • ISBN : 9789811321948
GET THIS BOOKPre-emptive Medicine: Public Health Aspects of Developmental Origins of Health and Disease

This book reviews public health activities such as awareness campaigns, health education, and strategies for health policy based on recent epidemiological studies that provide insights into epigenetic processes caused by environmental factors and developmental plasticity. It provides the latest concepts and findings on the public health aspects of Developmental Origins of Health and Disease (DOHaD) research regarding early prevention of non-communicable diseases (NCDs). Attention is especially paid to key issues, including strategies for the effective prevention of NCDs in developmental

Handbook of Life Course Health Development

Handbook of Life Course Health Development
  • Author : Neal Halfon,Christopher B. Forrest,Richard M. Lerner,Elaine M. Faustman
  • Publisher : Springer
  • Release Date : 2017-11-20
  • ISBN : 9783319471433
GET THIS BOOKHandbook of Life Course Health Development

This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important

Nutritional Epigenomics

Nutritional Epigenomics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-07-20
  • ISBN : 9780128173107
GET THIS BOOKNutritional Epigenomics

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity,

Early Life Origins of Ageing and Longevity

Early Life Origins of Ageing and Longevity
  • Author : Alexander Vaiserman
  • Publisher : Springer
  • Release Date : 2019-07-29
  • ISBN : 9783030249588
GET THIS BOOKEarly Life Origins of Ageing and Longevity

This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life. While other books in the field concentrate on the developmental origin of particular disorders, this volume offers a detailed guide to all important aspects of

Oxford Textbook of Nature and Public Health

Oxford Textbook of Nature and Public Health
  • Author : Matilda van den Bosch,William Bird
  • Publisher : Oxford University Press
  • Release Date : 2018-01-05
  • ISBN : 9780191038754
GET THIS BOOKOxford Textbook of Nature and Public Health

Human beings have always been affected by their surroundings. There are various health benefits linked to being able to access to nature; including increased physical activity, stress recovery, and the stimulation of child cognitive development. The Oxford Textbook of Nature and Public Health provides a broad and inclusive picture of the relationship between our own health and the natural environment. All aspects of this unique relationship are covered, ranging from disease prevention through physical activity in green spaces to innovative

Periconception in Physiology and Medicine

Periconception in Physiology and Medicine
  • Author : Alireza Fazeli,William V. Holt
  • Publisher : Springer
  • Release Date : 2017-08-31
  • ISBN : 9783319624143
GET THIS BOOKPericonception in Physiology and Medicine

This book presents a timely collection of reviews by experts in periconception and fertilization. The book provides a good introduction for those new to the field as well as those who have worked in this field for some time, but not have been able to keep up-to-date with recent advances on the topic. The book reviews the current knowledge in this field, then focuses its attention on short-term and long-term effects of the periconception period, both from a physiological and

Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity
  • Author : Alexey Moskalev,Alexander M. Vaiserman
  • Publisher : Academic Press
  • Release Date : 2017-11-17
  • ISBN : 9780128110836
GET THIS BOOKEpigenetics of Aging and Longevity

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in