Polycomb Group Proteins

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  • Publisher : Academic Press
  • Release : 01 January 2017
  • ISBN : 9780128098226
  • Page : 372 pages
  • Rating : 4.5/5 from 103 voters

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Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions. Provides topical coverage on accessory components that are known to be involved in PcG recruitment in Drosophila and their less understood role in mammals Includes dedicated sections on PRC1 complexes and PRC2 complexes for quick reference Features the role of RNA molecules in different aspects of Polycomb proteins involvement in epigenetic regulation, beginning with the key role of the Xist RNA in recruiting and spreading PcG complexes on the inactive X chromosome

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Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Vincenzo Pirrotta
  • Publisher : Academic Press
  • Release Date : 2017-01-01
  • ISBN : 9780128098226
GET THIS BOOKPolycomb Group Proteins

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The

Etiology and Morphogenesis of Congenital Heart Disease

Etiology and Morphogenesis of Congenital Heart Disease
  • Author : Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
  • Publisher : Springer
  • Release Date : 2016-06-24
  • ISBN : 9784431546283
GET THIS BOOKEtiology and Morphogenesis of Congenital Heart Disease

This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide

Identification and characterization of polycomb-group proteins

Identification and characterization of polycomb-group proteins
  • Author : Thihan Nyun,Reed College (Portland, Or.). Established Interdisciplinary Committee of Biochemistry and Molecular Biology
  • Publisher : Unknown
  • Release Date : 2000
  • ISBN : OCLC:268884884
GET THIS BOOKIdentification and characterization of polycomb-group proteins

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release Date : 2015-10-19
  • ISBN : 9780128004715
GET THIS BOOKEpigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a

Transcriptional Regulation by the Human Polycomb Group Protein Suppressor of Zeste-12

Transcriptional Regulation by the Human Polycomb Group Protein Suppressor of Zeste-12
  • Author : Antonis Kirmizis
  • Publisher : Unknown
  • Release Date : 2004
  • ISBN : WISC:89087432282
GET THIS BOOKTranscriptional Regulation by the Human Polycomb Group Protein Suppressor of Zeste-12

Introduction to Epigenetics

Introduction to Epigenetics
  • Author : Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
  • Publisher : Springer Nature
  • Release Date : 2021-03-23
  • ISBN : 9783030686703
GET THIS BOOKIntroduction to Epigenetics

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading

Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Chiara Lanzuolo,Beatrice Bodega
  • Publisher : Humana Press
  • Release Date : 2016-09-14
  • ISBN : 1493963783
GET THIS BOOKPolycomb Group Proteins

This volume presents the most recent technologies used in the Polycomb Group Proteins (PcG) field. Chapters detail state-of-the-art methods, creating a unique and comprehensive reference source for investigating Polycomb function in the nucleus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Polycomb Group Proteins: Method and Protocols

Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics
  • Author : Christophe Lavelle,Jean-Marc Victor
  • Publisher : Academic Press
  • Release Date : 2017-10-27
  • ISBN : 9780128035030
GET THIS BOOKNuclear Architecture and Dynamics

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists,

Epigenetics

Epigenetics
  • Author : C. David Allis
  • Publisher : CSHL Press
  • Release Date : 2007-01
  • ISBN : 9780879697242
GET THIS BOOKEpigenetics

The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and

Function of Polycomb Group Proteins During Seed Development

Function of Polycomb Group Proteins During Seed Development
  • Author : Aleksandra Erilova
  • Publisher : Unknown
  • Release Date : 2009
  • ISBN : OCLC:729965728
GET THIS BOOKFunction of Polycomb Group Proteins During Seed Development

Epigenetic Mechanisms of Gene Regulation

Epigenetic Mechanisms of Gene Regulation
  • Author : Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs
  • Publisher : Unknown
  • Release Date : 1996
  • ISBN : UOM:39015047449171
GET THIS BOOKEpigenetic Mechanisms of Gene Regulation

Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects

The Myelodysplastic Syndromes

The Myelodysplastic Syndromes
  • Author : Judit Várkonyi
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-03-23
  • ISBN : 9789400704404
GET THIS BOOKThe Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged 70 or older. It is believed that the true

Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Vincenzo Pirrotta
  • Publisher : Academic Press
  • Release Date : 2017-01-05
  • ISBN : 012809737X
GET THIS BOOKPolycomb Group Proteins

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The

Epigenetic Regulation of Skin Development and Regeneration

Epigenetic Regulation of Skin Development and Regeneration
  • Author : Vladimir A. Botchkarev,Sarah E. Millar
  • Publisher : Springer
  • Release Date : 2018-09-03
  • ISBN : 9783319167695
GET THIS BOOKEpigenetic Regulation of Skin Development and Regeneration

This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration

Function of Polycomb Group Proteins in Embryonic Stem Cells

Function of Polycomb Group Proteins in Embryonic Stem Cells
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • ISBN : OCLC:930655597
GET THIS BOOKFunction of Polycomb Group Proteins in Embryonic Stem Cells