New Approaches of Protein Function Prediction from Protein Interaction Networks

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  • Publisher : Academic Press
  • Release : 15 January 2017
  • ISBN : 0128098147
  • Page : 124 pages
  • Rating : 4.5/5 from 103 voters

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New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction. Provides innovative approaches and new developments targeting key issues in protein function prediction Presents heuristic ideas for further research in this challenging area

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New Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks
  • Author : Jingyu Hou
  • Publisher : Academic Press
  • Release Date : 2017-01-15
  • ISBN : 0128098147
GET THIS BOOKNew Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated

New Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks
  • Author : Jingyu Hou
  • Publisher : Academic Press
  • Release Date : 2017-01-13
  • ISBN : 9780128099445
GET THIS BOOKNew Approaches of Protein Function Prediction from Protein Interaction Networks

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated

Protein Function Prediction from Protein Interaction Network

Protein Function Prediction from Protein Interaction Network
  • Author : Sovan Saha,Piyali Chatterjee
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2013
  • ISBN : 3659402788
GET THIS BOOKProtein Function Prediction from Protein Interaction Network

Proteins perform every function in a cell. With the advent of genome sequencing projects for different organisms, large amounts of DNA and protein sequence data is available, whereas their biological function is still unknown in the most of the cases. Predicting protein function is the most challenging problem in post-genomic era. Using sequence homology, phylogenetic profiles, gene expression data, and function of unknown protein can be predicted. Recently, the large interaction networks constructed from high throughput techniques like Yeast2Hybrid

Data Management of Protein Interaction Networks

Data Management of Protein Interaction Networks
  • Author : Mario Cannataro,Pietro H. Guzzi
  • Publisher : John Wiley & Sons
  • Release Date : 2012-02-03
  • ISBN : 9781118103739
GET THIS BOOKData Management of Protein Interaction Networks

Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis,

Biomolecular Networks

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  • Author : Luonan Chen,Rui-Sheng Wang,Xiang-Sun Zhang
  • Publisher : John Wiley & Sons
  • Release Date : 2009-06-29
  • ISBN : 0470488050
GET THIS BOOKBiomolecular Networks

Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function.

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  • Publisher : Springer Science & Business Media
  • Release Date : 2013-08-28
  • ISBN : 9789400768031
GET THIS BOOKSystems Biology

Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing patent protection or being withdrawn from the market are simply not being replaced by new therapies – the pharmaceutical market model is no longer functioning effectively and most pharmaceutical companies are failing

Protein Interaction Networks in Health and Disease

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  • Author : Spyros Petrakis,Miguel A. Andrade-Navarro
  • Publisher : Frontiers Media SA
  • Release Date : 2016-10-19
  • ISBN : 9782889199822
GET THIS BOOKProtein Interaction Networks in Health and Disease

The identification and mapping of protein-protein interactions (PPIs) is a major goal in systems biology. Experimental data are currently produced in large scale using a variety of high-throughput assays in yeast or mammalian systems. Analysis of these data using computational tools leads to the construction of large protein interaction networks, which help researchers identify novel protein functions. However, our current view of protein interaction networks is still limited and there is an active field of research trying to further develop

Prediction of Protein Structures, Functions, and Interactions

Prediction of Protein Structures, Functions, and Interactions
  • Author : Janusz M. Bujnicki
  • Publisher : John Wiley & Sons
  • Release Date : 2008-12-23
  • ISBN : 0470741902
GET THIS BOOKPrediction of Protein Structures, Functions, and Interactions

The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions,

Learning and Intelligent Optimization: Designing, Implementing and Analyzing Effective Heuristics

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  • Author : Thomas Stützle
  • Publisher : Springer
  • Release Date : 2009-11-27
  • ISBN : 9783642111693
GET THIS BOOKLearning and Intelligent Optimization: Designing, Implementing and Analyzing Effective Heuristics

LION 3, the Third International Conference on Learning and Intelligent Op- mizatioN, was held during January 14–18 in Trento, Italy. The LION series of conferences provides a platform for researchers who are interested in the int- section of e?cient optimization techniques and learning. It is aimed at exploring the boundaries and uncharted territories between machine learning, arti?cial intelligence, mathematical programming and algorithms for hard optimization problems. The considerable interest in the topics covered by LION was re?ected by the

Advances in Protein Molecular and Structural Biology Methods

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  • Author : Timir Tripathi,Vikash Kumar Dubey
  • Publisher : Academic Press
  • Release Date : 2022-01-14
  • ISBN : 9780323902656
GET THIS BOOKAdvances in Protein Molecular and Structural Biology Methods

Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied

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  • Publisher : Springer Science & Business Media
  • Release Date : 2011-04-19
  • ISBN : 9789400708815
GET THIS BOOKProtein Function Prediction for Omics Era

Gene function annotation has been a central question in molecular biology. The importance of computational function prediction is increasing because more and more large scale biological data, including genome sequences, protein structures, protein-protein interaction data, microarray expression data, and mass spectrometry data, are awaiting biological interpretation. Traditionally when a genome is sequenced, function annotation of genes is done by homology search methods, such as BLAST or FASTA. However, since these methods are developed before the genomics era, conventional use of

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  • Release Date : 2012-04-13
  • ISBN : 9783642296277
GET THIS BOOKResearch in Computational Molecular Biology

This book constitutes the refereed proceedings of the 16th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2012, held in Barcelona, Spain, in April 2012. The 31 revised full papers presented together with 5 keynote lectures were carefully reviewed and selected from 200 submissions. The papers feature current research in all areas of computational molecular biology, including: molecular sequence analysis; recognition of genes and regulatory elements; molecular evolution; protein structure; structural genomics; analysis of gene expression; biological networks; sequencing and genotyping technologies; drug

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GET THIS BOOKAdvances in Biotechnology Research and Application: 2012 Edition

Advances in Biotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Advances in Biotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application / 2012 Edition has been produced

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  • ISBN : 9789813207820
GET THIS BOOKBiocomputing 2017 - Proceedings Of The Pacific Symposium

The Pacific Symposium on Biocomputing (PSB) 2017 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2017 will be held on January 4 - 8, 2017 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2017 will bring together top researchers from the US, the Asian

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