Nervous System Drug Delivery

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Read or download book entitled Nervous System Drug Delivery written by Russell R. Lonser and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Nervous System Drug Delivery book is available in the library.

  • Publisher : Academic Press
  • Release : 25 June 2019
  • ISBN : 0128139978
  • Page : 556 pages
  • Rating : 4.5/5 from 103 voters

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Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

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Nervous System Drug Delivery

Nervous System Drug Delivery
  • Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
  • Publisher : Academic Press
  • Release Date : 2019-06-25
  • ISBN : 0128139978
GET THIS BOOKNervous System Drug Delivery

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and

Drug Delivery to the Central Nervous System

Drug Delivery to the Central Nervous System
  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release Date : 2009-12-21
  • ISBN : 1607615282
GET THIS BOOKDrug Delivery to the Central Nervous System

Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-03
  • ISBN : 9781461491057
GET THIS BOOKDrug Delivery to the Brain

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics

Brain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems
  • Author : Huile Gao,Xiaoling Gao
  • Publisher : Academic Press
  • Release Date : 2018-09-20
  • ISBN : 9780128140024
GET THIS BOOKBrain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat

Drug Delivery to the Central Nervous System

Drug Delivery to the Central Nervous System
  • Author : Kewal K. Jain
  • Publisher : Humana
  • Release Date : 2016-08-23
  • ISBN : 1493961594
GET THIS BOOKDrug Delivery to the Central Nervous System

Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In

Nanomedicines for Brain Drug Delivery

Nanomedicines for Brain Drug Delivery
  • Author : Javier O. Morales,Pieter J. Gaillard
  • Publisher : Unknown
  • Release Date : 2021
  • ISBN : 107160838X
GET THIS BOOKNanomedicines for Brain Drug Delivery

Blood-Brain Barrier in Drug Discovery

Blood-Brain Barrier in Drug Discovery
  • Author : Li Di,Edward H. Kerns
  • Publisher : John Wiley & Sons
  • Release Date : 2015-02-02
  • ISBN : 9781118788356
GET THIS BOOKBlood-Brain Barrier in Drug Discovery

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design

The Blood Brain Barrier (BBB)

The Blood Brain Barrier (BBB)
  • Author : Gert Fricker,Melanie Ott,Anne Mahringer
  • Publisher : Springer
  • Release Date : 2014-10-24
  • ISBN : 9783662437872
GET THIS BOOKThe Blood Brain Barrier (BBB)

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series

Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier

Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
  • Publisher : National Academies Press
  • Release Date : 2018-05-29
  • ISBN : 9780309473101
GET THIS BOOKEnabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Bloodâ¬"Brain Barrier

Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the bloodâ€"brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors
  • Author : Prashant Kesharwani,Umesh Gupta
  • Publisher : Academic Press
  • Release Date : 2018-04-20
  • ISBN : 9780128122495
GET THIS BOOKNanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the

Nanotechnology Methods for Neurological Diseases and Brain Tumors

Nanotechnology Methods for Neurological Diseases and Brain Tumors
  • Author : Yasemin Gürsoy Özdemir,Sibel Bozdag Pehlivan,Emine Sekerdag
  • Publisher : Academic Press
  • Release Date : 2017-07-14
  • ISBN : 9780128038000
GET THIS BOOKNanotechnology Methods for Neurological Diseases and Brain Tumors

Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery

The Blood-Brain Barrier and Drug Delivery to the CNS

The Blood-Brain Barrier and Drug Delivery to the CNS
  • Author : Michael Bradbury,David Begley,Jorg Kreuter
  • Publisher : CRC Press
  • Release Date : 2000-05-16
  • ISBN : 0824703944
GET THIS BOOKThe Blood-Brain Barrier and Drug Delivery to the CNS

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research. Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from

Nanoparticles for Brain Drug Delivery

Nanoparticles for Brain Drug Delivery
  • Author : Carla Vitorino,Andreia Jorge,Alberto A.C.C. Pais
  • Publisher : CRC Press
  • Release Date : 2021-03-16
  • ISBN : 9781000245639
GET THIS BOOKNanoparticles for Brain Drug Delivery

In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including

Peptide Transport and Delivery into the Central Nervous System

Peptide Transport and Delivery into the Central Nervous System
  • Author : Laszlo Prokai,Katalin Prokai-Tatrai
  • Publisher : Birkhäuser
  • Release Date : 2012-12-06
  • ISBN : 9783034880497
GET THIS BOOKPeptide Transport and Delivery into the Central Nervous System

Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics developed as their agonists or antagonists could be useful in the treatment of these CNS maladies. However, peptides face a formidable obstacle in reaching the intended site of action due to the existence

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth de Lange,Robert G. Thorne
  • Publisher : Springer
  • Release Date : 2013-12-17
  • ISBN : 1461491045
GET THIS BOOKDrug Delivery to the Brain

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics