Diagnostic Molecular Pathology

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  • Publisher : Academic Press
  • Release : 05 October 2016
  • ISBN : 9780128011577
  • Page : 582 pages
  • Rating : 4.5/5 from 103 voters

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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

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Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2016-10-05
  • ISBN : 9780128011577
GET THIS BOOKDiagnostic Molecular Pathology

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The

Molecular Pathology

Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2017-11-09
  • ISBN : 9780128027875
GET THIS BOOKMolecular Pathology

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been

Molecular Hematology

Molecular Hematology
  • Author : Drew Provan,John Gribben
  • Publisher : John Wiley & Sons
  • Release Date : 2010-01-28
  • ISBN : 1444318543
GET THIS BOOKMolecular Hematology

Now in its third edition, Molecular Hematology has beenthoroughly updated to incorporate recent advances in molecularresearch. The aim of the book remains the same – to provide acore knowledge base for those with little exposure to molecularbiological techniques. Molecular biology has had a significant impact on theunderstanding of blood diseases and this book shows how moleculartechniques can be used in diagnosis and treatment. In each chapterthe authors summarize the impact made by molecular research on theunderstanding of the pathogenesis of the

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
  • Author : Debra G.B. Leonard
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-25
  • ISBN : 9780387332277
GET THIS BOOKMolecular Pathology in Clinical Practice

This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage,

Practical Oncologic Molecular Pathology

Practical Oncologic Molecular Pathology
  • Author : Yi Ding,Linsheng Zhang
  • Publisher : Springer Nature
  • Release Date : 2021-07-10
  • ISBN : 9783030732271
GET THIS BOOKPractical Oncologic Molecular Pathology

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2010-02-16
  • ISBN : 008092218X
GET THIS BOOKEssential Concepts in Molecular Pathology

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary

Basic Concepts of Molecular Pathology

Basic Concepts of Molecular Pathology
  • Author : Philip T. Cagle,Timothy Craig Allen
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-06-10
  • ISBN : 0387896260
GET THIS BOOKBasic Concepts of Molecular Pathology

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and

Molecular Pathology

Molecular Pathology
  • Author : John M. S. Bartlett,Abeer Shaaban,Fernando Schmitt
  • Publisher : Cambridge University Press
  • Release Date : 2015-11-05
  • ISBN : 9781107443464
GET THIS BOOKMolecular Pathology

Practical overview of current molecular techniques and their applications in each organ system, for practising and trainee pathologists.

Cell and Tissue Based Molecular Pathology E-Book

Cell and Tissue Based Molecular Pathology E-Book
  • Author : Raymond R. Tubbs,Mark H. Stoler
  • Publisher : Elsevier Health Sciences
  • Release Date : 2008-09-22
  • ISBN : 9781437719482
GET THIS BOOKCell and Tissue Based Molecular Pathology E-Book

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized

Diagnostic Molecular Pathology in Practice

Diagnostic Molecular Pathology in Practice
  • Author : Iris Schrijver
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-09-09
  • ISBN : 3642196772
GET THIS BOOKDiagnostic Molecular Pathology in Practice

This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book

Advances in Molecular Pathology, 2021, 4

Advances in Molecular Pathology, 2021, 4
  • Author : Gregory J. Tsongalis
  • Publisher : Elsevier
  • Release Date : 2021-10-17
  • ISBN : 0323813356
GET THIS BOOKAdvances in Molecular Pathology, 2021, 4

Advances in Molecular Pathology is an annual review publication that covers the current practices and latest developments in the field of Molecular Pathology. Each issue is divided into sections for comprehensive coverage of all subspecialty areas within molecular pathology, including, Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and special topics on COVID-19. The Editor-in-Chief of the publication is Dr. Gregory Tsongalis, a leading expert in the field. Topics covered this year include but are not limited to: Phenotype Association

Molecular Pathology and Diagnostics of Cancer

Molecular Pathology and Diagnostics of Cancer
  • Author : Domenico Coppola
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-29
  • ISBN : 9789400771925
GET THIS BOOKMolecular Pathology and Diagnostics of Cancer

Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests

Molecular Surgical Pathology

Molecular Surgical Pathology
  • Author : Liang Cheng,John N. Eble
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-11-15
  • ISBN : 9781461449003
GET THIS BOOKMolecular Surgical Pathology

Molecular Surgical Pathology provides a concise review of recent advancement of molecular pathology in each organ system. The text is intended as a “first knowledge base” in the rapidly evolving field of molecular pathology and is organized in a user friendly outline format. Each chapter is organ-based and covers important aspects of molecular pathology and its impact on our daily practice of surgical pathology. The topics presented herein constitute the fundamentals and core base of knowledge required for the daily

Neurodegeneration

Neurodegeneration
  • Author : Dennis Dickson,Roy O. Weller
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-09
  • ISBN : 9781444341232
GET THIS BOOKNeurodegeneration

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within

In Situ Molecular Pathology and Co-expression Analyses

In Situ Molecular Pathology and Co-expression Analyses
  • Author : Gerard J. Nuovo
  • Publisher : Academic Press
  • Release Date : 2020-09-03
  • ISBN : 9780128206546
GET THIS BOOKIn Situ Molecular Pathology and Co-expression Analyses

Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods.