Models of Seizures and Epilepsy

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  • Publisher : Academic Press
  • Release : 14 June 2017
  • ISBN : 9780128040676
  • Page : 1178 pages
  • Rating : 4.5/5 from 103 voters

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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé
  • Publisher : Academic Press
  • Release Date : 2017-06-14
  • ISBN : 9780128040676
GET THIS BOOKModels of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

Introduction to Epilepsy

Introduction to Epilepsy
  • Author : Gonzalo Alarcón,Antonio Valentín
  • Publisher : Cambridge University Press
  • Release Date : 2012-04-26
  • ISBN : 9780521691581
GET THIS BOOKIntroduction to Epilepsy

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.

Epileptic Seizures and the EEG

Epileptic Seizures and the EEG
  • Author : Andrea Varsavsky,Iven Mareels,Mark Cook
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • ISBN : 9781439812044
GET THIS BOOKEpileptic Seizures and the EEG

A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic

Encyclopedia of Basic Epilepsy Research

Encyclopedia of Basic Epilepsy Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2009-05-27
  • ISBN : 9780123739612
GET THIS BOOKEncyclopedia of Basic Epilepsy Research

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent

Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
  • Author : Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
  • Publisher : Oxford University Press
  • Release Date : 2012-06-01
  • ISBN : 9780199842599
GET THIS BOOKJasper's Basic Mechanisms of the Epilepsies

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these

Epilepsy

Epilepsy
  • Author : Philip A. Schwartzkroin
  • Publisher : Cambridge University Press
  • Release Date : 1993-06-17
  • ISBN : 9780521392983
GET THIS BOOKEpilepsy

This book considers a number of major concepts and models in epilepsy research, to advance understanding of the basic mechanisms involved.

Epilepsy

Epilepsy
  • Author : Jong Rho,Raman Sankar,Carl E. Stafstrom
  • Publisher : CRC Press
  • Release Date : 2010-06-18
  • ISBN : 9781420085600
GET THIS BOOKEpilepsy

Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo

Animal Models of Epilepsy

Animal Models of Epilepsy
  • Author : Scott C. Baraban
  • Publisher : Humana Press
  • Release Date : 2009-05-29
  • ISBN : 1603272623
GET THIS BOOKAnimal Models of Epilepsy

In this book, investigators examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species. This is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.

Computational Neuroscience in Epilepsy

Computational Neuroscience in Epilepsy
  • Author : Ivan Soltesz,Kevin Staley
  • Publisher : Academic Press
  • Release Date : 2011-09-02
  • ISBN : 0080559530
GET THIS BOOKComputational Neuroscience in Epilepsy

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters

Astrocytes and Epilepsy

Astrocytes and Epilepsy
  • Author : Jacqueline A. Hubbard,Devin K. Binder
  • Publisher : Academic Press
  • Release Date : 2016-07-05
  • ISBN : 9780128026243
GET THIS BOOKAstrocytes and Epilepsy

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of

New Antiepileptic Drugs

New Antiepileptic Drugs
  • Author : Francesco Pisani
  • Publisher : Elsevier Science Limited
  • Release Date : 1991
  • ISBN : UOM:39015024821962
GET THIS BOOKNew Antiepileptic Drugs

The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general,

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
  • Author : Daniel Laskowitz,Gerald Grant
  • Publisher : CRC Press
  • Release Date : 2015-12-01
  • ISBN : 9781498766579
GET THIS BOOKTranslational Research in Traumatic Brain Injury

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps

Epilepsy

Epilepsy
  • Author : David W. McCandless
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-11-02
  • ISBN : 1461403618
GET THIS BOOKEpilepsy

The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less

Generalized Non-Convulsive Epilepsy: Focus on GABA-B Receptors

Generalized Non-Convulsive Epilepsy: Focus on GABA-B Receptors
  • Author : C. Marescaux,M. Vergnes,R. Bernasconi
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-08
  • ISBN : 9783709192061
GET THIS BOOKGeneralized Non-Convulsive Epilepsy: Focus on GABA-B Receptors

Generalized non convulsive epilepsy (GNCE), also called absence or petit mal epilepsy, is a disease appearing during childhood. EEG, clinical, pharmacological and genetic characteristics differ from those of convulsive or focal epilepsies. No underlying structural or biochemical abnormality has been identified for generalized absence seizures and the etiology of this disorder is unknown. It is unlikely that the precise pathophysiology of GNCE can be resolved in studies that focus on humans. Therefore a number of animal models reproducing the human

The Epilepsies

The Epilepsies
  • Author : Chrysostomos P. Panayiotopoulos
  • Publisher : Bladon Medical Pub
  • Release Date : 2005
  • ISBN : UOM:39015062497741
GET THIS BOOKThe Epilepsies

The Epilepsies: Seizures, Syndromes and Management is the latest work from one of the world's leading experts and offers an exhaustive account of the classification and management of epileptic disorders. In thirteen chapters, Dr Panayiotopoulos gives clear and didactic guidance on the diagnosis, treatment and ongoing management of the full spectrum of epileptic syndromes with an insight and perception that only he can bring to the subject.This text is published in full colour throughout and is complemented by a