Models of Seizures and Epilepsy

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  • Publisher : Academic Press
  • Release : 14 June 2017
  • ISBN : 9780128040676
  • Page : 1178 pages
  • Rating : 4.5/5 from 103 voters

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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

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Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé
  • Publisher : Academic Press
  • Release Date : 2017-06-14
  • ISBN : 9780128040676
GET THIS BOOKModels of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

Seizures and Epilepsy

Seizures and Epilepsy
  • Author : Jerome Engel Jr
  • Publisher : Oxford University Press
  • Release Date : 2013-01-31
  • ISBN : 9780195328547
GET THIS BOOKSeizures and Epilepsy

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
  • Author : Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
  • Publisher : Oxford University Press
  • Release Date : 2012-06-01
  • ISBN : 9780199842599
GET THIS BOOKJasper's Basic Mechanisms of the Epilepsies

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these

Epileptic Seizures and the EEG

Epileptic Seizures and the EEG
  • Author : Andrea Varsavsky,Iven Mareels,Mark Cook
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • ISBN : 9781439812044
GET THIS BOOKEpileptic Seizures and the EEG

A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic

Animal Models of Epilepsy

Animal Models of Epilepsy
  • Author : Scott C. Baraban
  • Publisher : Humana Press
  • Release Date : 2009-05-29
  • ISBN : 1603272623
GET THIS BOOKAnimal Models of Epilepsy

In this book, investigators examine several novel models of epilepsy in mice as well as in genetically tractable "simple" species. This is an ideal guide for scientists who wish to expand our understanding of the pathogenesis of this neurological disorder.

Epilepsy

Epilepsy
  • Author : Philip A. Schwartzkroin
  • Publisher : Cambridge University Press
  • Release Date : 1993-06-17
  • ISBN : 9780521392983
GET THIS BOOKEpilepsy

This book considers a number of major concepts and models in epilepsy research, to advance understanding of the basic mechanisms involved.

Introduction to Epilepsy

Introduction to Epilepsy
  • Author : Gonzalo Alarcón,Antonio Valentín
  • Publisher : Cambridge University Press
  • Release Date : 2012-04-26
  • ISBN : 9780521691581
GET THIS BOOKIntroduction to Epilepsy

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.

Encyclopedia of Basic Epilepsy Research

Encyclopedia of Basic Epilepsy Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2009-05-27
  • ISBN : 9780123739612
GET THIS BOOKEncyclopedia of Basic Epilepsy Research

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent

Epilepsy

Epilepsy
  • Author : Jong Rho,Raman Sankar,Carl E. Stafstrom
  • Publisher : CRC Press
  • Release Date : 2010-06-18
  • ISBN : 9781420085600
GET THIS BOOKEpilepsy

Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo

Epilepsy

Epilepsy
  • Author : David W. McCandless
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-11-02
  • ISBN : 1461403618
GET THIS BOOKEpilepsy

The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less

Astrocytes and Epilepsy

Astrocytes and Epilepsy
  • Author : Jacqueline A. Hubbard,Devin K. Binder
  • Publisher : Academic Press
  • Release Date : 2016-07-05
  • ISBN : 9780128026243
GET THIS BOOKAstrocytes and Epilepsy

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of

Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Solomon L. Mosh,Aristea S. Galanopoulou
  • Publisher : Academic Press
  • Release Date : 2017-06-16
  • ISBN : 0128040661
GET THIS BOOKModels of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

Computational Neuroscience in Epilepsy

Computational Neuroscience in Epilepsy
  • Author : Ivan Soltesz,Kevin Staley
  • Publisher : Academic Press
  • Release Date : 2011-09-02
  • ISBN : 0080559530
GET THIS BOOKComputational Neuroscience in Epilepsy

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy
  • Author : Divya Vohora
  • Publisher : Unknown
  • Release Date : 2021
  • ISBN : 1071612549
GET THIS BOOKExperimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research. Chapters also cover techniques to screen the effective leads for the treatment of refractory seizures of pharmacoresistant epilepsy and invertebrate, non-mammalian models. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists

Atlas of Epilepsies

Atlas of Epilepsies
  • Author : S.R. Benbadis,R.G. Beran,A.T. Berg,J. Engel, Jr.,A.S. Galanopoulou,P.W. Kaplan,M. Koutroumanidis,S.L. Moshe,D.R. Nordli, Jr.,J.M. Serratosa,S.M. Sisodiya,W.O. Tatum,T. Valeta,A. Wilner
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-09-20
  • ISBN : 9781848821279
GET THIS BOOKAtlas of Epilepsies

Atlas of Epilepsies is a landmark, all-encompassing, illustrated reference work and hands-on guide to the diagnosis, management and treatment of epilepsy in all its forms and across all age groups. The premier text in the field with over one thousand images, the Atlas’s highly illustrative approach tackles the difficult subject of epileptic seizures and epileptic syndromes, accompanied by sequential photographs of each management step. Intraoperative photographs are accompanied by detailed figure legends describing nuances, subtleties, and the thought processes