MicroRNA in Regenerative Medicine

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Read or download book entitled MicroRNA in Regenerative Medicine written by Chandan K. Sen and published by Elsevier in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that MicroRNA in Regenerative Medicine book is available in the library.

  • Publisher : Elsevier
  • Release : 26 November 2014
  • ISBN : 9780124058583
  • Page : 1288 pages
  • Rating : 4.5/5 from 103 voters

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This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering Multi-colour text layout with 150 colour figures to illustrate important findings Take home messages encapsulate key lessons throughout text Short chapters offer focused discussion and clear ‘voice’

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MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
  • Author : Chandan K. Sen
  • Publisher : Elsevier
  • Release Date : 2014-11-26
  • ISBN : 9780124058583
GET THIS BOOKMicroRNA in Regenerative Medicine

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational

RNAi and microRNA-Mediated Gene Regulation in Stem Cells

RNAi and microRNA-Mediated Gene Regulation in Stem Cells
  • Author : Baohong Zhang,Edmund J. Stellwag
  • Publisher : Humana Press
  • Release Date : 2011-08-24
  • ISBN : 1607617706
GET THIS BOOKRNAi and microRNA-Mediated Gene Regulation in Stem Cells

Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. In RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications, expert authors from laboratories across the globe contribute an accessible compendium of up-to-date, proven methods focused on the study of the titular topic. Divided into

Cell Engineering and Regeneration

Cell Engineering and Regeneration
  • Author : Jeffrey M. Gimble,Darja Marolt,Richard Oreffo,Heinz Redl,Susanne Wolbank
  • Publisher : Springer
  • Release Date : 2018-03-01
  • ISBN : 3319370766
GET THIS BOOKCell Engineering and Regeneration

This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection

Transcriptional and Translational Regulation of Stem Cells

Transcriptional and Translational Regulation of Stem Cells
  • Author : Gary Hime,Helen Abud
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-05-22
  • ISBN : 9789400766211
GET THIS BOOKTranscriptional and Translational Regulation of Stem Cells

This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of

Mesenchymal Stem Cell Derived Exosomes

Mesenchymal Stem Cell Derived Exosomes
  • Author : Yaoliang Tang,Buddhadeb Dawn
  • Publisher : Academic Press
  • Release Date : 2015-09-02
  • ISBN : 9780128004975
GET THIS BOOKMesenchymal Stem Cell Derived Exosomes

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the

Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • ISBN : 0123814235
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.

Hormones, Metabolism and the Benefits of Exercise

Hormones, Metabolism and the Benefits of Exercise
  • Author : Bruce Spiegelman
  • Publisher : Springer
  • Release Date : 2018-03-07
  • ISBN : 9783319727905
GET THIS BOOKHormones, Metabolism and the Benefits of Exercise

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones

Role of Exosomes in Biological Communication Systems

Role of Exosomes in Biological Communication Systems
  • Author : Faisal A. Alzahrani,Islam M. Saadeldin
  • Publisher : Springer Nature
  • Release Date : 2020-11-20
  • ISBN : 9789811565991
GET THIS BOOKRole of Exosomes in Biological Communication Systems

This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential

Novel roles of non-coding brain RNAs in health and disease

Novel roles of non-coding brain RNAs in health and disease
  • Author : Hermona Soreq
  • Publisher : Frontiers E-books
  • Release Date : 2014-10-23
  • ISBN : 9782889193097
GET THIS BOOKNovel roles of non-coding brain RNAs in health and disease

Non-coding RNAs (ncRNAs), and in particular microRNAs are rapidly becoming the focus of research interest in numerous basic and translational fields, including brain research; and their importance for many aspects in brain functioning merits special discussion. The wide-scope, multi-targeted and highly efficient manner of ncRNA regulatory activities draws attention to this topic by many, but the available research and analysis tools and experimental protocols are still at their infancy, and calls for special discussion given their importance for many aspects

Stem Cells & Regenerative Medicine

Stem Cells & Regenerative Medicine
  • Author : Krishnarao Appasani,Raghu K. Appasani
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-11-01
  • ISBN : 9781607618607
GET THIS BOOKStem Cells & Regenerative Medicine

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both

Current Perspectives in microRNAs (miRNA)

Current Perspectives in microRNAs (miRNA)
  • Author : Shao-Yao Ying
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-09-12
  • ISBN : 9781402085338
GET THIS BOOKCurrent Perspectives in microRNAs (miRNA)

Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new

Cancer Stem Cells: New Horizons in Cancer Therapies

Cancer Stem Cells: New Horizons in Cancer Therapies
  • Author : Surajit Pathak,Antara Banerjee
  • Publisher : Springer Nature
  • Release Date : 2020-10-17
  • ISBN : 9789811551208
GET THIS BOOKCancer Stem Cells: New Horizons in Cancer Therapies

This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic

Regenerative Pharmacology

Regenerative Pharmacology
  • Author : George J. Christ,Karl-Erik Andersson
  • Publisher : Cambridge University Press
  • Release Date : 2013-04-15
  • ISBN : 9780521899499
GET THIS BOOKRegenerative Pharmacology

A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.

Regenerative Medicine - from Protocol to Patient

Regenerative Medicine - from Protocol to Patient
  • Author : Gustav Steinhoff
  • Publisher : Springer
  • Release Date : 2016-04-19
  • ISBN : 9783319276106
GET THIS BOOKRegenerative Medicine - from Protocol to Patient

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative

Stem Cell Regulators

Stem Cell Regulators
  • Author : Gerald Litwack
  • Publisher : Academic Press
  • Release Date : 2011
  • ISBN : 9780123860156
GET THIS BOOKStem Cell Regulators

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and