In Vivo Models to Study Angiogenesis

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  • Publisher : Academic Press
  • Release : 18 August 2017
  • ISBN : 9780128140215
  • Page : 112 pages
  • Rating : 4.5/5 from 103 voters

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In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available. Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling. Provides information on the most common assays to study angiogenesis in vivo Presents an ideal reference for those interested in angiogenesis as a normal and vital process in growth and development Covers wound healing, the formation of granulation tissue, and the transition of tumors from benign to malignant

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In Vivo Models to Study Angiogenesis

In Vivo Models to Study Angiogenesis
  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Release Date : 2017-08-18
  • ISBN : 9780128140215
GET THIS BOOKIn Vivo Models to Study Angiogenesis

In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents

Angiogenesis Assays

Angiogenesis Assays
  • Author : Carolyn A. Staton,Claire Lewis,Roy Bicknell
  • Publisher : John Wiley & Sons
  • Release Date : 2007-01-11
  • ISBN : 9780470029343
GET THIS BOOKAngiogenesis Assays

Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo,

Angiogenesis

Angiogenesis
  • Author : William D. Figg,Judah Folkman
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-05-24
  • ISBN : 9780387715186
GET THIS BOOKAngiogenesis

Dr. Judah Folkman is considered the "father of angiogenesis." Because of Folkman's discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. Angiogenesis: An Integrative Approach from Science to Medicine is a comprehensive, concise summary of tumor angiogenesis. It is an up-to-date and authoritative reference for the angiogenesis field as it relates to oncology. This book represents the first collection in a volume of which Folkman is co-editor. Folkman has authored nearly 400 original papers

Physiologic and Pathologic Angiogenesis

Physiologic and Pathologic Angiogenesis
  • Author : Dan Simionescu,Agneta Simionescu
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-04-05
  • ISBN : 9789535130239
GET THIS BOOKPhysiologic and Pathologic Angiogenesis

The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that

The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis

The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
  • Author : Domenico Ribatti
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-01-28
  • ISBN : 9789048138456
GET THIS BOOKThe Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis

The chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane which serves as a gas exchange surface and its function is supported by a dense capillary network. Because of its extensive vascularization and easy accessibility, the CAM has been broadly used to study the morpho-functional aspects of the angiogenesis process in vivo and to investigate the efficacy and mechanisms of action of pro-angiogenic and anti-angiogenic natural and synthetic molecules. The CAM is a suitable site for transplanting tissues, which can

In Vivo Models of Inflammation

In Vivo Models of Inflammation
  • Author : Christopher S. Stevenson,Lisa A. Marshall,Douglas W. Morgan
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-11-10
  • ISBN : 9783764375201
GET THIS BOOKIn Vivo Models of Inflammation

In Vivo Models of Inflammation (Vol. 1) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first, describing and updating the standard models that are most utilized for specific disease areas. New models are included exploring emerging areas of inflammation research.

Angiogenesis in Brain Tumors

Angiogenesis in Brain Tumors
  • Author : Matthias Kirsch,Peter McL. Black
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9781441988713
GET THIS BOOKAngiogenesis in Brain Tumors

- Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians - Text includes clinical trials - Written by leaders in the field

In Vivo Models of Inflammation

In Vivo Models of Inflammation
  • Author : Douglas W. Morgan,Lisa A. Marshall
  • Publisher : Springer Science & Business Media
  • Release Date : 1999
  • ISBN : 3764358769
GET THIS BOOKIn Vivo Models of Inflammation

Purpose of In vivo Models of Inflammation is to provide the biomedical researcher in both the pharmaceutical industry and academia with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. The aim of this second edition is to act as a complement to the first by describing and updating the standard models that are most utilized for specific disease areas. In addition, this 2nd edition includes new models exploring emerging

The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications

The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications
  • Author : Enrique Zudaire,Frank Cuttitta
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-11-29
  • ISBN : 9789400745810
GET THIS BOOKThe Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications

Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases. These extraordinary advancements have been built upon a vast array of diverse

The Vascular Endothelium

The Vascular Endothelium
  • Author : Domenico Ribatti,Francesco Pezzella
  • Publisher : Academic Press
  • Release Date : 2022-05-29
  • ISBN : 9780128243923
GET THIS BOOKThe Vascular Endothelium

The Vascular Endothelium: A Holistic Approach for Oncology provides novel and integrated knowledge on the endothelial cells as a crucial component involved in the growth of different organs in both physiological and pathological conditions. By covering diverse aspects of anatomy, embryology, molecular biology and pathology, it details the important role of the endothelium for the pathogenesis of cancer and how this knowledge can improve the outcome of cancer research. The content is split in six parts: appearance and evolution of

Angiogenesis: In Vivo Systems

Angiogenesis: In Vivo Systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2009-02-12
  • ISBN : 0080921663
GET THIS BOOKAngiogenesis: In Vivo Systems

Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or

Tumor Vascularization

Tumor Vascularization
  • Author : Domenico Ribatti,Francesco Pezzella
  • Publisher : Academic Press
  • Release Date : 2020-01-21
  • ISBN : 9780128194942
GET THIS BOOKTumor Vascularization

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a

Vasculogenic Mimicry

Vasculogenic Mimicry
  • Author : Emily Marques dos Reis,Fernanda Berti
  • Publisher : Springer Nature
  • Release Date : 2022-06-30
  • ISBN : 9781071624036
GET THIS BOOKVasculogenic Mimicry

This volume provides detailed protocols for the identification and understanding of vasculogenic mimicry process in vitro and in vivo, in addition to protocols for microscopy and histology. Chapters guide readers through different materials, commercial and homemade scaffolds, Matrigel, cancer spheroids, 3D tissue constructs, vasculogenic processes, and mathematical model building. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and

Mechanisms of Angiogenesis

Mechanisms of Angiogenesis
  • Author : Matthias Clauss,Georg Breier
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-11-22
  • ISBN : 3764364599
GET THIS BOOKMechanisms of Angiogenesis

Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro-

Tumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion
  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Release Date : 2021-04-04
  • ISBN : 9780128228043
GET THIS BOOKTumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs