In Vitro Toxicology

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  • Publisher : Academic Press
  • Release : 13 November 2017
  • ISBN : 9780128047712
  • Page : 248 pages
  • Rating : 4.5/5 from 103 voters

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In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing

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In Vitro Toxicology

In Vitro Toxicology
  • Author : Alok Dhawan,Seok (Soga) Kwon
  • Publisher : Academic Press
  • Release Date : 2017-11-13
  • ISBN : 9780128047712
GET THIS BOOKIn Vitro Toxicology

In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance

In Vitro Toxicology Systems

In Vitro Toxicology Systems
  • Author : Anna Bal-Price,Paul Jennings
  • Publisher : Humana Press
  • Release Date : 2014-05-01
  • ISBN : 1493905201
GET THIS BOOKIn Vitro Toxicology Systems

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism,

In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols
  • Author : Sheila O’Hare,C. K. Atterwill
  • Publisher : Humana Press
  • Release Date : 1995-05-04
  • ISBN : UOM:39015037494393
GET THIS BOOKIn Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols is a collection of proven, state-of-the-art methods that toxicologists can use in carrying out laboratory studies. The book's expert contributors offer a variety of efficient in vitro toxicology techniques that can be applied regularly in your lab, or can serve as the fundamental basis for the establishment of novel techniques in working laboratories. All the procedures are highly reliable. Also included are ex vivo techniques, whose development embraces the twin aims of reduction and refinement

In Vitro Toxicology, Second Edition

In Vitro Toxicology, Second Edition
  • Author : Shayne C. Gad
  • Publisher : CRC Press
  • Release Date : 2000-11-02
  • ISBN : 9781560327691
GET THIS BOOKIn Vitro Toxicology, Second Edition

Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists

Principles of Toxicology Testing

Principles of Toxicology Testing
  • Author : Frank A Barile
  • Publisher : CRC Press
  • Release Date : 2013-04-02
  • ISBN : 9781842145296
GET THIS BOOKPrinciples of Toxicology Testing

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, includin

Genetic Toxicology Testing

Genetic Toxicology Testing
  • Author : Ray Proudlock
  • Publisher : Academic Press
  • Release Date : 2016-05-28
  • ISBN : 9780128010068
GET THIS BOOKGenetic Toxicology Testing

Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria. An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
  • Author : Dave Allen,Mike D. Waters
  • Publisher : Royal Society of Chemistry
  • Release Date : 2013
  • ISBN : 9781849736527
GET THIS BOOKReducing, Refining and Replacing the Use of Animals in Toxicity Testing

This thought-provoking book describes the ever-expanding toolbox of methods now available to reduce, refine, or replace animal usage in toxicity testing.

The History of Alternative Test Methods in Toxicology

The History of Alternative Test Methods in Toxicology
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-10-20
  • ISBN : 9780128136980
GET THIS BOOKThe History of Alternative Test Methods in Toxicology

The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and

In Vitro Toxicology

In Vitro Toxicology
  • Author : Alan M. Goldberg
  • Publisher : Mary Ann Liebert
  • Release Date : 1985
  • ISBN : UCAL:$B319480
GET THIS BOOKIn Vitro Toxicology

Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for In Vitro Toxicology
  • Author : G. Stacey,Alan Doyle,Margherita Ferro
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-29
  • ISBN : 9789401709965
GET THIS BOOKCell Culture Methods for In Vitro Toxicology

Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues

Validation of Alternative Methods for Toxicity Testing

Validation of Alternative Methods for Toxicity Testing
  • Author : Chantra Eskes,Maurice Whelan
  • Publisher : Springer
  • Release Date : 2016-09-26
  • ISBN : 9783319338262
GET THIS BOOKValidation of Alternative Methods for Toxicity Testing

This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are

Green Toxicology

Green Toxicology
  • Author : Alexandra Maertens
  • Publisher : Royal Society of Chemistry
  • Release Date : 2022-02-16
  • ISBN : 9781839164408
GET THIS BOOKGreen Toxicology

Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding

Adverse Effects of Engineered Nanomaterials

Adverse Effects of Engineered Nanomaterials
  • Author : Bengt Fadeel,Antonio Pietroiusti,Anna A. Shvedova
  • Publisher : Academic Press
  • Release Date : 2012-01-27
  • ISBN : 9780123869401
GET THIS BOOKAdverse Effects of Engineered Nanomaterials

An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety. Multi-authored book written by leading US and European experts on nanotoxicology and nanomedicine Discusses the health implications and a clinical translation of experimental data in this area Takes a schematic, non-exhaustive approach to summarize the most important research data in this field Includes a glossary, with a brief explanation of the

Evidence Based in Vitro Toxicology

Evidence Based in Vitro Toxicology
  • Author : Sebastian Hoffmann
  • Publisher : Unknown
  • Release Date : 2005
  • ISBN : OCLC:314852688
GET THIS BOOKEvidence Based in Vitro Toxicology

Animal Experimentation

Animal Experimentation
  • Author : Kathrin Herrmann,Kimberley Jayne
  • Publisher : Human-Animal Studies
  • Release Date : 2019
  • ISBN : 9004356185
GET THIS BOOKAnimal Experimentation

Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.