Immunomodulatory Biomaterials

Book Immunomodulatory Biomaterials Cover

Read or download book entitled Immunomodulatory Biomaterials written by Stephen F. Badylak and published by Woodhead Publishing in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Immunomodulatory Biomaterials book is available in the library.

  • Publisher : Woodhead Publishing
  • Release : 30 July 2021
  • ISBN : 9780128214565
  • Page : 294 pages
  • Rating : 4.5/5 from 103 voters

Download Immunomodulatory Biomaterials in PDF, Epub and Kindle

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area

GET THIS BOOK

Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
  • Author : Stephen F. Badylak,Jennifer Elisseeff
  • Publisher : Woodhead Publishing
  • Release Date : 2021-07-30
  • ISBN : 9780128214565
GET THIS BOOKImmunomodulatory Biomaterials

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative

Biomaterials and Immune Response

Biomaterials and Immune Response
  • Author : Nihal Engin Vrana
  • Publisher : CRC Press
  • Release Date : 2018-07-20
  • ISBN : 9781351377553
GET THIS BOOKBiomaterials and Immune Response

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted

Cellular Response to Biomaterials

Cellular Response to Biomaterials
  • Author : Lucy Di Silvio
  • Publisher : Elsevier
  • Release Date : 2008-12-22
  • ISBN : 9781845695477
GET THIS BOOKCellular Response to Biomaterials

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility
  • Author : Masoud Mozafari
  • Publisher : Woodhead Publishing
  • Release Date : 2020-06-17
  • ISBN : 9780081029688
GET THIS BOOKHandbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and

Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System
  • Author : Laura Santambrogio
  • Publisher : Springer
  • Release Date : 2015-09-04
  • ISBN : 9783319180458
GET THIS BOOKBiomaterials in Regenerative Medicine and the Immune System

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as

Immunomodulatory Biomaterials to Mitigate Material-induced Host Responses

Immunomodulatory Biomaterials to Mitigate Material-induced Host Responses
  • Author : Yoon Kyung Kim
  • Publisher : Unknown
  • Release Date : 2013
  • ISBN : 1303444976
GET THIS BOOKImmunomodulatory Biomaterials to Mitigate Material-induced Host Responses

The foreign body response to biomaterial implants has been a major challenge in translating many medical devices into the clinic. The presence of inflammatory cells around the implanted device prevents its functional interaction with the surrounding tissue, and although some inflammation may be desirable to mediate the healing process, a persistent inflammatory response will eventually lead to device failure. Significant efforts to reduce foreign body response have been largely focused on developing hydrophilic and anti-fouling coating materials, however, simply preventing

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy
  • Author : Anubhab Mukherjee,Vijay Sagar Madamsetty
  • Publisher : Springer Nature
  • Release Date : 2022-05-31
  • ISBN : 9783031016691
GET THIS BOOKEmerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators,

Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing
  • Author : Nihal Engin Vrana,Amir M. Ghaemmaghami,Pinar Zorlutuna
  • Publisher : Frontiers Media SA
  • Release Date : 2019-05-15
  • ISBN : 9782889458226
GET THIS BOOKAdverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse immune reactions to biomaterials are important bottlenecks for translation of novel biomaterials for clinical use. Moreover, recent advances in highthrough-put biomaterial discovery and synthetic biology, while providing exciting new veues, also significantly increases potential risks related to the in vivo reactions to these new materials. For example, the novel materials might have unintended biological activities due to their natural building blocks. In this perspective, biomaterial field needs i) better understanding of cell/biomaterial interactions at systems level; ii) development

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
  • Author : Bruna Corradetti
  • Publisher : Springer
  • Release Date : 2016-11-30
  • ISBN : 9783319454337
GET THIS BOOKThe Immune Response to Implanted Materials and Devices

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development

Biomaterials and Immune Response

Biomaterials and Immune Response
  • Author : Nihal Engin Vrana
  • Publisher : CRC Press
  • Release Date : 2018-07-20
  • ISBN : 9781351377560
GET THIS BOOKBiomaterials and Immune Response

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted

Extracellular Vesicles

Extracellular Vesicles
  • Author : Dr Wojciech Chrzanowski,Professor Chwee Teck Lim,Dr Sally Yunsun Kim
  • Publisher : Royal Society of Chemistry
  • Release Date : 2021-10-29
  • ISBN : 9781788018944
GET THIS BOOKExtracellular Vesicles

Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
  • Author : Mario Barbosa,M Cristina L Martins
  • Publisher : Woodhead Publishing
  • Release Date : 2017-09-25
  • ISBN : 9780081008522
GET THIS BOOKPeptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for

Biomaterials Science

Biomaterials Science
  • Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
  • Publisher : Academic Press
  • Release Date : 2020-05-23
  • ISBN : 9780128161388
GET THIS BOOKBiomaterials Science

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in

Polymeric Biomaterials for Healthcare Applications

Polymeric Biomaterials for Healthcare Applications
  • Author : Kokkarachedu Varaprasad
  • Publisher : Woodhead Publishing
  • Release Date : 2022-05-16
  • ISBN : 9780323852340
GET THIS BOOKPolymeric Biomaterials for Healthcare Applications

Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in healthcare and biomedicine. The book provides a fundamental overview of polymers and processing technologies to allow clinical scientists to explore the use of these polymers in alternative applications. A wide variety of healthcare applications are covered, including treatment for autoimmune diseases and bacterial infections, tissue engineering, gene delivery, wound dressing, and more. The book provides a core introductory

Engineering Materials for Stem Cell Regeneration

Engineering Materials for Stem Cell Regeneration
  • Author : Faheem A. Sheikh
  • Publisher : Springer Nature
  • Release Date : 2021-10-23
  • ISBN : 9789811644207
GET THIS BOOKEngineering Materials for Stem Cell Regeneration

This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials