History of Risk Assessment in Toxicology

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  • Publisher : Academic Press
  • Release : 20 September 2017
  • ISBN : 9780128095430
  • Page : 50 pages
  • Rating : 4.5/5 from 103 voters

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History of Risk Assessment in Toxicology guides the reader through the historical narrative of the evolution of risk assessment thinking in human and environmental practices. Risk assessment concepts are used in many different professional practice areas. In the health and environmental practices of risk assessment, the critical issue is often what chemical concentration in air, water, food, or a solid substance is acceptable, or considered not to result in any adverse effect. The book reviews examples from early scientific and health studies to showcase the foundations of risk assessment. The book also explores the development of risk assessment as practiced by major regulatory bodies such as the US Food and Drug Administration (FDA), the Occupational Safety & Health Administration (OSHA), and the US Environmental Protection Agency (EPA) to reveal how risk assessment has evolved in the 20th and 21st centuries. Modern technology has created opportunities in silicon in vitro, computational modeling, omics, and big data techniques to assess the toxicity of chemicals, while traditional approaches to risk assessment are being challenged with new and innovative approaches. Finally, current issues being debated and tested in risk assessment are outlined with possible future avenues suggested. Presents the first dedicated history on the evolution of risk assessment in toxicology Reviews the development of major US and EU regulatory bodies Provides a context to current debates surrounding the future of risk assessment Reviews examples from early scientific and health studies to showcase the foundations of risk assessment

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History of Risk Assessment in Toxicology

History of Risk Assessment in Toxicology
  • Author : Sol Bobst
  • Publisher : Academic Press
  • Release Date : 2017-09-20
  • ISBN : 9780128095430
GET THIS BOOKHistory of Risk Assessment in Toxicology

History of Risk Assessment in Toxicology guides the reader through the historical narrative of the evolution of risk assessment thinking in human and environmental practices. Risk assessment concepts are used in many different professional practice areas. In the health and environmental practices of risk assessment, the critical issue is often what chemical concentration in air, water, food, or a solid substance is acceptable, or considered not to result in any adverse effect. The book reviews examples from early scientific and

Environmental Risk Assessment

Environmental Risk Assessment
  • Author : Ted Simon
  • Publisher : CRC Press
  • Release Date : 2019-12-06
  • ISBN : 9781000754117
GET THIS BOOKEnvironmental Risk Assessment

The purpose of risk assessment is to support science-based decisions about how to solve complex societal problems. Indeed, the problems humankind faces in the 21st century have many social, political, and technical complexities. Environmental risk assessment in particular is of increasing importance as health and safety regulations grow and become more complicated. Environmental Risk Assessment: A Toxicological Approach, 2nd Edition looks at various factors relating to exposure and toxicity, human health, and risk. In addition to the original chapters being

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure
  • Author : Aristidis M. Tsatsakis
  • Publisher : Elsevier
  • Release Date : 2021-08-01
  • ISBN : 9780323853583
GET THIS BOOKToxicological Risk Assessment and Multi-System Health Impacts from Exposure

Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into

Toxicological Risk Assessment for Beginners

Toxicological Risk Assessment for Beginners
  • Author : José A. Torres,Sol Bobst
  • Publisher : Springer
  • Release Date : 2015-03-27
  • ISBN : 9783319127514
GET THIS BOOKToxicological Risk Assessment for Beginners

This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book

Toxicological Risk Assessment of Chemicals

Toxicological Risk Assessment of Chemicals
  • Author : Elsa Nielsen,Grete Ostergaard,John Christian Larsen
  • Publisher : CRC Press
  • Release Date : 2008-02-21
  • ISBN : 9781420006940
GET THIS BOOKToxicological Risk Assessment of Chemicals

Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk

Regulatory Toxicology in the European Union

Regulatory Toxicology in the European Union
  • Author : Tim Marrs,Kevin Woodward
  • Publisher : Royal Society of Chemistry
  • Release Date : 2018-02-21
  • ISBN : 9781788014045
GET THIS BOOKRegulatory Toxicology in the European Union

Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of

Toxicology and Risk Assessment

Toxicology and Risk Assessment
  • Author : Helmut Greim,Robert Snyder
  • Publisher : John Wiley & Sons
  • Release Date : 2018-08-10
  • ISBN : 9781119135920
GET THIS BOOKToxicology and Risk Assessment

Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise

Environmental Pollutant Exposures and Public Health

Environmental Pollutant Exposures and Public Health
  • Author : R M Harrison
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-10-27
  • ISBN : 9781839160448
GET THIS BOOKEnvironmental Pollutant Exposures and Public Health

Both genes and environment have profound effects upon our health. While some environmental factors such as polluted air are high in the public consciousness, there are many other pathways for people’s exposure to toxic chemicals, such as through food, water and contaminated land. It is not only chemicals that can affect health; environmental radioactivity, pathogenic organisms and our changing climate also have implications for public health, and all contribute to the global burden of disease, leading to both disability

Calculated Risks

Calculated Risks
  • Author : Joseph V. Rodricks
  • Publisher : Cambridge University Press
  • Release Date : 2006-11-23
  • ISBN : 9781139459518
GET THIS BOOKCalculated Risks

Safeguarding economic prosperity, whilst protecting human health and the environment, is at the forefront of scientific and public interest. This book provides a practical and balanced view on toxicology, control, risk assessment and risk management, addressing the interplay between science and public health policy. This revised edition provides a detailed analysis on chemical and by-product exposure, how they enter the body and the suitability of imposed safety limits. Chapters on dose, with particular emphasis on children and vulnerable subpopulations, reproductive

Science and Decisions

Science and Decisions
  • Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Improving Risk Analysis Approaches Used by the U.S. EPA
  • Publisher : National Academies Press
  • Release Date : 2009-03-24
  • ISBN : 9780309120463
GET THIS BOOKScience and Decisions

Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology
  • Author : Carey N. Pope,Jing Liu
  • Publisher : Academic Press
  • Release Date : 2020-02
  • ISBN : 9780128136027
GET THIS BOOKAn Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple" molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations,

Risk Assessment of Chemicals: An Introduction

Risk Assessment of Chemicals: An Introduction
  • Author : C.J. van Leeuwen,T.G. Vermeire
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-09-18
  • ISBN : 9781402061011
GET THIS BOOKRisk Assessment of Chemicals: An Introduction

At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products,

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment
  • Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
  • Publisher : National Academies Press
  • Release Date : 2000-12-21
  • ISBN : 9780309070867
GET THIS BOOKScientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances,

Fundamentals Of Aquatic Toxicology

Fundamentals Of Aquatic Toxicology
  • Author : Gary M. Rand
  • Publisher : CRC Press
  • Release Date : 1995-10-05
  • ISBN : 1560320915
GET THIS BOOKFundamentals Of Aquatic Toxicology

This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated

Risk Assessment in the Federal Government

Risk Assessment in the Federal Government
  • Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on the Institutional Means for Assessment of Risks to Public Health
  • Publisher : National Academies Press
  • Release Date : 1983-02-01
  • ISBN : 9780309033497
GET THIS BOOKRisk Assessment in the Federal Government

The regulation of potentially hazardous substances has become a controversial issue. This volume evaluates past efforts to develop and use risk assessment guidelines, reviews the experience of regulatory agencies with different administrative arrangements for risk assessment, and evaluates various proposals to modify procedures. The book's conclusions and recommendations can be applied across the entire field of environmental health.