Handbook of Pharmacogenomics and Stratified Medicine

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Read or download book entitled Handbook of Pharmacogenomics and Stratified Medicine written by Sandosh Padmanabhan and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Handbook of Pharmacogenomics and Stratified Medicine book is available in the library.

  • Publisher : Academic Press
  • Release : 28 April 2014
  • ISBN : 9780123868831
  • Page : 1118 pages
  • Rating : 4.5/5 from 103 voters

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Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies– next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics

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Handbook of Pharmacogenomics and Stratified Medicine

Handbook of Pharmacogenomics and Stratified Medicine
  • Author : Sandosh Padmanabhan
  • Publisher : Academic Press
  • Release Date : 2014-04-28
  • ISBN : 9780123868831
GET THIS BOOKHandbook of Pharmacogenomics and Stratified Medicine

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists,

Handbook of Personalized Medicine

Handbook of Personalized Medicine
  • Author : Ioannis S. Vizirianakis
  • Publisher : CRC Press
  • Release Date : 2014-02-12
  • ISBN : 9789814411196
GET THIS BOOKHandbook of Personalized Medicine

This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases,

Advancing Healthcare Through Personalized Medicine

Advancing Healthcare Through Personalized Medicine
  • Author : Priya Hays
  • Publisher : Springer Nature
  • Release Date : 2021
  • ISBN : 9783030801007
GET THIS BOOKAdvancing Healthcare Through Personalized Medicine

This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate he healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and

Textbook of Personalized Medicine

Textbook of Personalized Medicine
  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release Date : 2015-03-17
  • ISBN : 9781493925537
GET THIS BOOKTextbook of Personalized Medicine

Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory

Applying Pharmacogenomics in Therapeutics

Applying Pharmacogenomics in Therapeutics
  • Author : Xiaodong Feng,Hong-Guang Xie
  • Publisher : CRC Press
  • Release Date : 2016-01-06
  • ISBN : 9781498782456
GET THIS BOOKApplying Pharmacogenomics in Therapeutics

Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a

Economic Dimensions of Personalized and Precision Medicine

Economic Dimensions of Personalized and Precision Medicine
  • Author : Ernst R. Berndt
  • Publisher : National Bureau of Economic Re
  • Release Date : 2019-04-22
  • ISBN : 9780226611068
GET THIS BOOKEconomic Dimensions of Personalized and Precision Medicine

Personalized and precision medicine (PPM)--the targeting of therapies according to an individual's genetic, environmental, or lifestyle characteristics--is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated

Preclinical Development Handbook

Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-21
  • ISBN : 0470249048
GET THIS BOOKPreclinical Development Handbook

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques. Each chapter was written by one or more leading experts in the field.

Oxford American Handbook of Cardiology

Oxford American Handbook of Cardiology
  • Author : Jeffrey Bender
  • Publisher : Oxford University Press
  • Release Date : 2010-10-27
  • ISBN : 9780195389692
GET THIS BOOKOxford American Handbook of Cardiology

The Oxford American Handbook of Cardiology captures the latest knowledge in the rapidly expanding field of cardiovascular medicine and delivers essential, practical advice for clinical cardiologists.

Handbook of Biomarkers and Precision Medicine

Handbook of Biomarkers and Precision Medicine
  • Author : Claudio Carini,Mark Fidock,Alain van Gool
  • Publisher : CRC Press
  • Release Date : 2019-04-16
  • ISBN : 9780429574627
GET THIS BOOKHandbook of Biomarkers and Precision Medicine

"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into

Omics in Clinical Practice

Omics in Clinical Practice
  • Author : Yu Liu
  • Publisher : CRC Press
  • Release Date : 2014-06-20
  • ISBN : 9781771880602
GET THIS BOOKOmics in Clinical Practice

This book serves as an introduction to genomics, proteomics, and transcriptomics, putting these fields in relation to human disease and ailments. The various chapters consider the role of translation and personalized medicine, as well as pathogen detection, evolution, and infection, in relation to genomics, proteomics, and transcriptomics. The topic of companion diagnostics is also covered. The book is broken into five sections. Part I examines the connection between omics and human disease. Part II looks at the applications for the

Pharmacoepigenetics

Pharmacoepigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-06-04
  • ISBN : 9780128139400
GET THIS BOOKPharmacoepigenetics

Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the

The Road from Nanomedicine to Precision Medicine

The Road from Nanomedicine to Precision Medicine
  • Author : Shaker A. Mousa,Raj Bawa,Gerald F. Audette
  • Publisher : CRC Press
  • Release Date : 2020-01-06
  • ISBN : 9781000043495
GET THIS BOOKThe Road from Nanomedicine to Precision Medicine

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected

Genomics in Drug Discovery and Development

Genomics in Drug Discovery and Development
  • Author : Dimitri Semizarov,Eric Blomme
  • Publisher : John Wiley & Sons
  • Release Date : 2008-11-03
  • ISBN : 9780470409763
GET THIS BOOKGenomics in Drug Discovery and Development

Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages, including microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory personnel, discovery toxicologists, and safety scientists, drug development professionals, and

The Genetics of African Populations in Health and Disease

The Genetics of African Populations in Health and Disease
  • Author : Muntaser E. Ibrahim,Charles N. Rotimi
  • Publisher : Cambridge University Press
  • Release Date : 2019-12-19
  • ISBN : 9781107072022
GET THIS BOOKThe Genetics of African Populations in Health and Disease

A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.

Concepts in Pharmacogenomics

Concepts in Pharmacogenomics
  • Author : Martin M. Zdanowicz
  • Publisher : ASHP
  • Release Date : 2010
  • ISBN : 9781585282340
GET THIS BOOKConcepts in Pharmacogenomics

The new science of pharmacogenomics aims to understand how an individual's genetic composition affects his/her response to a specific drug or class of drugs. By studying such characteristics as drug metabolizing enzymes, drug transporter activity, and receptor sensitivity, a pharmacist is better able to prescribe the right drug the first time. If you are pharmacist, resident, or student curious about this new field, start with Concepts in Pharmacogenomics. In this practical guide, you will find an overview of the