Gap Junction Structure and Chemical Regulation

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  • Publisher : Academic Press
  • Release : 16 February 2019
  • ISBN : 9780128163801
  • Page : 226 pages
  • Rating : 4.5/5 from 103 voters

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Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension. Contains comprehensive, historical coverage on direct cell-to-cell communication Provides detailed coverage of gap junction channel structure and regulation, with extensive coverage of the direct role of calmodulin in channel gating Delivers a thorough description of models proposed for the chemical gating of gap junction channels

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Gap Junction Structure and Chemical Regulation

Gap Junction Structure and Chemical Regulation
  • Author : Camillo Peracchia
  • Publisher : Academic Press
  • Release Date : 2019-02-16
  • ISBN : 9780128163801
GET THIS BOOKGap Junction Structure and Chemical Regulation

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established

Molecular Biology of the Cell

Molecular Biology of the Cell
  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • ISBN : 0815332181
GET THIS BOOKMolecular Biology of the Cell

Gap Junctions: Molecular Basis of Cell Communication in Health and Disease

Gap Junctions: Molecular Basis of Cell Communication in Health and Disease
  • Author : Dale J. Benos,Camillo Peracchia
  • Publisher : Gulf Professional Publishing
  • Release Date : 1999-12-28
  • ISBN : 0125506457
GET THIS BOOKGap Junctions: Molecular Basis of Cell Communication in Health and Disease

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to

Gap Junctions in the Nervous System

Gap Junctions in the Nervous System
  • Author : David C. Spray,Rolf Dermietzel
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-29
  • ISBN : 9783662219355
GET THIS BOOKGap Junctions in the Nervous System

This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.

Cell-Cell Channels

Cell-Cell Channels
  • Author : František Baluška,Dieter Volkmann,Peter W. Barlow
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-08-10
  • ISBN : 9780387469577
GET THIS BOOKCell-Cell Channels

he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to

Handbook of Membrane Channels

Handbook of Membrane Channels
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2012-12-02
  • ISBN : 9780323138901
GET THIS BOOKHandbook of Membrane Channels

This handbook provides a thorough account of recent directions in membrane channel research. Each subject is covered in terms of channel biophysics, pharmacology, and molecular biology. The introductory chapter reviews methodologies of molecular biology currently used for studying molecular structure and function of membrane channels and specific domains in channel proteins.

Gap Junction Channels and Hemichannels

Gap Junction Channels and Hemichannels
  • Author : Donglin Bai,Juan C. Sáez
  • Publisher : CRC Press
  • Release Date : 2016-07-25
  • ISBN : 1498738621
GET THIS BOOKGap Junction Channels and Hemichannels

Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel research has recently exploded and became one of the most active areas of cell biology. Numerous novel approaches and techniques have been developed, but there is no single book dedicated to the unique

Astrocytes and Epilepsy

Astrocytes and Epilepsy
  • Author : Jacqueline A. Hubbard,Devin K. Binder
  • Publisher : Academic Press
  • Release Date : 2016-07-05
  • ISBN : 9780128026243
GET THIS BOOKAstrocytes and Epilepsy

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of

Government Reports Announcements & Index

Government Reports Announcements & Index
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1989
  • ISBN : MSU:31293009753967
GET THIS BOOKGovernment Reports Announcements & Index

Junctional Complexes of Epithelial Cells

Junctional Complexes of Epithelial Cells
  • Author : Gregory R. Bock,Sarah Clark
  • Publisher : John Wiley & Sons
  • Release Date : 2008-04-30
  • ISBN : 9780470513415
GET THIS BOOKJunctional Complexes of Epithelial Cells

Epithelial cells cover the outer and inner surfaces of the body, forming a selective polarized barrier between the intercellualar space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial organization and function are specialized membrane domains--desmosomes, gap junctions, and occluding junctions. The contributors to this multidisciplinary symposium volume explore the nature of such junctional structures, focusing on the molecular organization and diversity of their constituent proteins, their formation and control, and interactions with ions

Discovering the Brain

Discovering the Brain
  • Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
  • Publisher : National Academies Press
  • Release Date : 1992-01-01
  • ISBN : 9780309045292
GET THIS BOOKDiscovering the Brain

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the

Regulation of Tissue Oxygenation, Second Edition

Regulation of Tissue Oxygenation, Second Edition
  • Author : Roland N. Pittman
  • Publisher : Biota Publishing
  • Release Date : 2016-08-18
  • ISBN : 9781615047215
GET THIS BOOKRegulation of Tissue Oxygenation, Second Edition

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection,

Anatomy and Physiology

Anatomy and Physiology
  • Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
  • Publisher : Unknown
  • Release Date : 2013-04-25
  • ISBN : 1947172808
GET THIS BOOKAnatomy and Physiology

Gap Junctions

Gap Junctions
  • Author : Rudolf Werner
  • Publisher : IOS Press
  • Release Date : 1998
  • ISBN : 9051993749
GET THIS BOOKGap Junctions

This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells. It describes the latest results in gap junctions research, the structural and functional characterization of cell-cell channels, the assembly and degradation of gap junctions, the expression and function of gap junctions in different tissues, knockout studies of gap junction genes, the regulation of connexin gene expression, and the functions of gap junctions in development and cancer.

Pattern Formation in Zebrafish

Pattern Formation in Zebrafish
  • Author : Lilianna Solnica-Krezel
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-04-17
  • ISBN : 9783540460411
GET THIS BOOKPattern Formation in Zebrafish

Authored by leading experts in the field, this book provides the first comprehensive overview of the mechanisms of early patterning and morphogenesis in zebrafish. It summarizes the current knowledge and the key questions for the next decade of research.