Epigenetics of Aging and Longevity

Book Epigenetics of Aging and Longevity Cover

Read or download book entitled Epigenetics of Aging and Longevity written by Alexey Moskalev and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Epigenetics of Aging and Longevity book is available in the library.

  • Publisher : Academic Press
  • Release : 17 November 2017
  • ISBN : 9780128110836
  • Page : 544 pages
  • Rating : 4.5/5 from 103 voters

Download Epigenetics of Aging and Longevity in PDF, Epub and Kindle

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

GET THIS BOOK

Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity
  • Author : Alexey Moskalev,Alexander M. Vaiserman
  • Publisher : Academic Press
  • Release Date : 2017-11-17
  • ISBN : 9780128110836
GET THIS BOOKEpigenetics of Aging and Longevity

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in

Epigenetics of Aging

Epigenetics of Aging
  • Author : Trygve O. Tollefsbol
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-11-11
  • ISBN : 9781441906397
GET THIS BOOKEpigenetics of Aging

Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major

Lifespan

Lifespan
  • Author : David A. Sinclair,Matthew D. LaPlante
  • Publisher : Atria Books
  • Release Date : 2019-09-10
  • ISBN : 9781501191978
GET THIS BOOKLifespan

A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory

Biomarkers of Human Aging

Biomarkers of Human Aging
  • Author : Alexey Moskalev
  • Publisher : Springer Nature
  • Release Date : 2019-09-13
  • ISBN : 9783030249700
GET THIS BOOKBiomarkers of Human Aging

This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts

Senescence

Senescence
  • Author : Jolanta Dorszewska,Wojciech Kozubski
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-08-30
  • ISBN : 9789535134619
GET THIS BOOKSenescence

In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different

Longevity Genes

Longevity Genes
  • Author : Gil Atzmon, PhD
  • Publisher : Springer
  • Release Date : 2015-04-27
  • ISBN : 9781493924042
GET THIS BOOKLongevity Genes

The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular

Human Aging

Human Aging
  • Author : Calogero Caruso,Giuseppina Candore
  • Publisher : Academic Press
  • Release Date : 2021-05-11
  • ISBN : 9780128227374
GET THIS BOOKHuman Aging

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and

Younger You

Younger You
  • Author : Kara N. Fitzgerald
  • Publisher : Hachette UK
  • Release Date : 2022-01-18
  • ISBN : 9780306924859
GET THIS BOOKYounger You

Based on the groundbreaking study that shaved three years off a subjects' age in just eight weeks, discover a proven, accessible plan to prevent diseases and reduce your biological age. It’s true: getting older is inevitable and your chronological age can only move in one direction. But you also have a biological age, which scientists can measure by assessing how your genes are expressed through epigenetics. Exciting new research shows that your bio age can actually move in reverse—

Anti-aging Drugs

Anti-aging Drugs
  • Author : Alexander M Vaiserman
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-02-01
  • ISBN : 9781782624356
GET THIS BOOKAnti-aging Drugs

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points

Nutritional Epigenomics

Nutritional Epigenomics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-07-20
  • ISBN : 9780128173107
GET THIS BOOKNutritional Epigenomics

Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity,

Nutrition and Epigenetics

Nutrition and Epigenetics
  • Author : Emily Ho,Frederick Domann
  • Publisher : CRC Press
  • Release Date : 2014-10-16
  • ISBN : 9781482203820
GET THIS BOOKNutrition and Epigenetics

Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text: Documents the epigenetic effect of antioxidants and their health benefits Adds to the

Epigenetics of Exercise and Sports

Epigenetics of Exercise and Sports
  • Author : Stuart Raleigh
  • Publisher : Academic Press
  • Release Date : 2021-07-13
  • ISBN : 9780128209370
GET THIS BOOKEpigenetics of Exercise and Sports

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve O. Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2012
  • ISBN : 9780123884152
GET THIS BOOKEpigenetics in Human Disease

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable,

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Elsevier
  • Release Date : 2014-05-02
  • ISBN : 9780124059221
GET THIS BOOKTransgenerational Epigenetics

Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release Date : 2015-10-19
  • ISBN : 9780128004715
GET THIS BOOKEpigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a