Environmental Epigenetics in Toxicology and Public Health

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  • Publisher : Academic Press
  • Release : 18 October 2020
  • ISBN : 9780128199695
  • Page : 364 pages
  • Rating : 4.5/5 from 103 voters

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Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures. Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification Features contributions from international experts in the field

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Environmental Epigenetics in Toxicology and Public Health

Environmental Epigenetics in Toxicology and Public Health
  • Author : Rebecca Fry
  • Publisher : Academic Press
  • Release Date : 2020-10-18
  • ISBN : 9780128199695
GET THIS BOOKEnvironmental Epigenetics in Toxicology and Public Health

Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as

Environmental Epigenetics

Environmental Epigenetics
  • Author : L. Joseph Su,Tung-chin Chiang
  • Publisher : Springer
  • Release Date : 2015-05-18
  • ISBN : 9781447166788
GET THIS BOOKEnvironmental Epigenetics

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended

Toxicoepigenetics

Toxicoepigenetics
  • Author : Shaun D. McCullough,Dana Dolinoy
  • Publisher : Academic Press
  • Release Date : 2018-11-02
  • ISBN : 9780128124345
GET THIS BOOKToxicoepigenetics

Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects

Systems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health
  • Author : Rebecca Fry
  • Publisher : Academic Press
  • Release Date : 2015-06-11
  • ISBN : 9780128015681
GET THIS BOOKSystems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an

Toxicology and Epigenetics

Toxicology and Epigenetics
  • Author : Saura C. Sahu
  • Publisher : John Wiley & Sons
  • Release Date : 2012-08-23
  • ISBN : 9781118349069
GET THIS BOOKToxicology and Epigenetics

Epigenetics is the study of both heritable and non-heritablechanges in the regulation of gene activity and expression thatoccur without an alteration in the DNA sequence. Thisdynamic and rapidly developing discipline is making its impactacross the biomedical sciences, in particular in toxicology whereepigenetic differences can mean that different individuals responddifferently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensionalcharacter of this emerging area of toxicology, describingcutting-edge molecular technologies to unravel epigenetic changes,the use of in vivo and

The Exposome

The Exposome
  • Author : Gary W Miller
  • Publisher : Elsevier
  • Release Date : 2013-11-16
  • ISBN : 9780124172180
GET THIS BOOKThe Exposome

The Exposome: A Primer is the first book dedicated to exposomics, detailing the purpose and scope of this emerging field of study, its practical applications and how it complements a broad range of disciplines. Genetic causes account for up to a third of all complex diseases. (As genomic approaches improve, this is likely to rise.) Environmental factors also influence human disease but, unlike with genetics, there is no standard or systematic way to measure the influence of environmental exposures. The

New Frontiers in Environmental Sciences and Human Health: NIEHS 2006-2011 Strategic Plan

New Frontiers in Environmental Sciences and Human Health: NIEHS 2006-2011 Strategic Plan
  • Author : Anonim
  • Publisher : DIANE Publishing
  • Release Date : 2022-09-29
  • ISBN : 9781437906868
GET THIS BOOKNew Frontiers in Environmental Sciences and Human Health: NIEHS 2006-2011 Strategic Plan

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
  • Author : Cheryl S Rosenfeld
  • Publisher : Academic Press
  • Release Date : 2015-10-10
  • ISBN : 9780128016725
GET THIS BOOKThe Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological

Epigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders
  • Author : Nagy Youssef
  • Publisher : Academic Press
  • Release Date : 2022-02-25
  • ISBN : 9780128230626
GET THIS BOOKEpigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders, Volume 31 in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA or gene expression following prolonged stress and/or trauma. Sections introduce both genetic and psychiatric foundations, including modes of epigenetic modification and gene expression that result from stress, as well as the medical knowledge required to understand stress related disorders and resilience. From here, chapters discuss epigenetic research techniques applied in recent studies, including epigenome-wide association studies (EWAS) of PTSD

Developmental Human Behavioral Epigenetics

Developmental Human Behavioral Epigenetics
  • Author : Livio Provenzi,Rosario Montirosso
  • Publisher : Academic Press
  • Release Date : 2020-11-12
  • ISBN : 9780128192634
GET THIS BOOKDevelopmental Human Behavioral Epigenetics

Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug

Epigenetics of Exercise and Sports

Epigenetics of Exercise and Sports
  • Author : Stuart Raleigh
  • Publisher : Academic Press
  • Release Date : 2021-07-13
  • ISBN : 9780128209370
GET THIS BOOKEpigenetics of Exercise and Sports

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports

Twin and Family Studies of Epigenetics

Twin and Family Studies of Epigenetics
  • Author : Shuai Li,John Hopper
  • Publisher : Academic Press
  • Release Date : 2021-08-31
  • ISBN : 9780128209523
GET THIS BOOKTwin and Family Studies of Epigenetics

Twin and Family Studies of Epigenetics, Volume 29, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic

Epigenetics and DNA Damage

Epigenetics and DNA Damage
  • Author : Miriam Galvonas Jasiulionis
  • Publisher : Academic Press
  • Release Date : 2022-08-14
  • ISBN : 9780323910828
GET THIS BOOKEpigenetics and DNA Damage

Although scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood. Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment. Epigenetics and DNA Damage, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation. Early

Veterans and Agent Orange

Veterans and Agent Orange
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Eleventh Biennial Update)
  • Publisher : National Academies Press
  • Release Date : 2018-12-20
  • ISBN : 9780309477192
GET THIS BOOKVeterans and Agent Orange

From 1962 to 1971, the U.S. military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D

Post-transcriptional Gene Regulation in Human Disease

Post-transcriptional Gene Regulation in Human Disease
  • Author : Buddhi Prakash Jain,Shyamal K. Goswami,Tapan Sharma
  • Publisher : Academic Press
  • Release Date : 2022-08-12
  • ISBN : 9780323914246
GET THIS BOOKPost-transcriptional Gene Regulation in Human Disease

Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study