Drug Repurposing in Cancer Therapy

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Read or download book entitled Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Drug Repurposing in Cancer Therapy book is available in the library.

  • Publisher : Academic Press
  • Release : 29 July 2020
  • ISBN : 9780128199039
  • Page : 458 pages
  • Rating : 4.5/5 from 103 voters

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Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

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Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To,William C.S. Cho
  • Publisher : Academic Press
  • Release Date : 2020-07-29
  • ISBN : 9780128199039
GET THIS BOOKDrug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and

Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To,William C.S. Cho
  • Publisher : Academic Press
  • Release Date : 2020-08-17
  • ISBN : 9780128196687
GET THIS BOOKDrug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and

Drug Repurposing

Drug Repurposing
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-12-02
  • ISBN : 9781839685200
GET THIS BOOKDrug Repurposing

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to

Drug Repositioning: Current Advances and Future Perspectives

Drug Repositioning: Current Advances and Future Perspectives
  • Author : Yuhei Nishimura,Hideaki Hara
  • Publisher : Frontiers Media SA
  • Release Date : 2019-01-11
  • ISBN : 9782889456963
GET THIS BOOKDrug Repositioning: Current Advances and Future Perspectives

Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically,

Repurposed Drugs Targeting Cancer Signaling Pathways: Dissecting New Mechanisms of Action Through in vitro and in vivo Analyses

Repurposed Drugs Targeting Cancer Signaling Pathways: Dissecting New Mechanisms of Action Through in vitro and in vivo Analyses
  • Author : Alma D. Campos-Parra,Carlos Pérez-Plasencia,Teresita Padilla-Benavides,Eduardo López-Urrutia
  • Publisher : Frontiers Media SA
  • Release Date : 2021-11-29
  • ISBN : 9782889717163
GET THIS BOOKRepurposed Drugs Targeting Cancer Signaling Pathways: Dissecting New Mechanisms of Action Through in vitro and in vivo Analyses

Conference on Drug Design and Discovery Technologies

Conference on Drug Design and Discovery Technologies
  • Author : Manikanta Murahari,Lakshmi Sundar,Soma Chaki,Vasanthanathan Poongavanam,Pritesh Bhat,Usha Y Nayak
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-11-20
  • ISBN : 9781788018623
GET THIS BOOKConference on Drug Design and Discovery Technologies

This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at Ramaiah University of Applied Sciences, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader receives a good understanding of the scope of the field. Aimed at scientists, students, regulators, academics and consultants throughout the world, this book is an ideal resource for anyone interested in the

Artificial Intelligence in Oncology Drug Discovery and Development

Artificial Intelligence in Oncology Drug Discovery and Development
  • Author : John Cassidy,Belle Taylor
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-09-09
  • ISBN : 9781789846898
GET THIS BOOKArtificial Intelligence in Oncology Drug Discovery and Development

There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of cancer increases, the current paradigm in drug development is unsustainable. In this book, we discuss the development of techniques in machine learning for improving the efficiency of oncology drug development

Chloroquine for Cancer, Covid-19, and Disease

Chloroquine for Cancer, Covid-19, and Disease
  • Author : Justus Hope
  • Publisher : Unknown
  • Release Date : 2020-05
  • ISBN : 0998055409
GET THIS BOOKChloroquine for Cancer, Covid-19, and Disease

This is a book for physicians and the lay public to notify all about the benefits of repurposed drugs. These drugs can be used for life-saving purposes when no other effective treatments exist. Drug combinations aimed at Terminal Cancer and the Coronavirus Pandemic are both addressed.

Drug Repurposing for COVID-19 Therapy

Drug Repurposing for COVID-19 Therapy
  • Author : Filippo Drago,Rafael Maldonado
  • Publisher : Frontiers Media SA
  • Release Date : 2021-10-14
  • ISBN : 9782889714858
GET THIS BOOKDrug Repurposing for COVID-19 Therapy

Anticancer Drugs

Anticancer Drugs
  • Author : Niamh M O’Boyle,Mary J Meegan
  • Publisher : MDPI
  • Release Date : 2019-10-11
  • ISBN : 9783039215867
GET THIS BOOKAnticancer Drugs

The past decades have seen major developments in the understanding of the cellular and molecular biology of cancer. Significant progress has been achieved regarding long-term survival for the patients of many cancers with the use of tamoxifen for treatment of breast cancer, treatment of chronic myeloid leukaemia with imatinib, and the success of biological drugs. The transition from cytotoxic chemotherapy to targeted cancer drug discovery and development has resulted in an increasing selection of tools available to oncologists. In this

Natural Products and Cancer Drug Discovery

Natural Products and Cancer Drug Discovery
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-07-05
  • ISBN : 9789535133131
GET THIS BOOKNatural Products and Cancer Drug Discovery

This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our

Drug Repurposing and Repositioning

Drug Repurposing and Repositioning
  • Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Translating Genomic-Based Research for Health
  • Publisher : National Academies Press
  • Release Date : 2014-08-08
  • ISBN : 9780309302074
GET THIS BOOKDrug Repurposing and Repositioning

Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs - a process referred to as drug repurposing or repositioning. Historically, drug repurposing has been largely an unintentional, serendipitous process that took place when a drug was found to have an

Oxidative Stress

Oxidative Stress
  • Author : Canhua Huang,Yuanyuan Zhang
  • Publisher : Springer Nature
  • Release Date : 2021-05-27
  • ISBN : 9789811605222
GET THIS BOOKOxidative Stress

This book offers a systematic review of the cutting-edge knowledge in stress medicine. Cellular redox imbalance, resulting from overproduction of reactive oxide species (ROS), leads to oxidative stress and subsequent occurrence and development of many diseases, such as cancer, diabetes, pain, etc. In addition, ROS can induce post-translational modification of proteins and play roles through redox signaling pathways. In this book, the authors attempt to re-define the key concepts in oxidative stress, such as oxidative eustress and oxidative distress, revisit

Drug Repurposing

Drug Repurposing
  • Author : Shailendra K. Saxena
  • Publisher : BoD – Books on Demand
  • Release Date : 2022-06-01
  • ISBN : 9781839699573
GET THIS BOOKDrug Repurposing

This book focuses on various aspects and applications of drug repurposing, the understanding of which is important for treating diseases. Due to the high costs and time associated with the new drug discovery process, the inclination toward drug repurposing is increasing for common as well as rare diseases. A major focus of this book is understanding the role of drug repurposing to develop drugs for infectious diseases, including antivirals, antibacterial and anticancer drugs, as well as immunotherapeutics.

Metal-based Anticancer Agents

Metal-based Anticancer Agents
  • Author : Anne Vessières,Angela Casini,Samuel M Meier-Menches
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-04-05
  • ISBN : 9781788017671
GET THIS BOOKMetal-based Anticancer Agents

Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes