Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

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  • Publisher : Elsevier
  • Release : 15 April 2019
  • ISBN : 9780128157244
  • Page : 458 pages
  • Rating : 4.5/5 from 103 voters

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Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases

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Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2019-04-15
  • ISBN : 9780128157244
GET THIS BOOKDiscovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases

Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene

Neglected Tropical Diseases

Neglected Tropical Diseases
  • Author : David C. Swinney,Michael P. Pollastri
  • Publisher : John Wiley & Sons
  • Release Date : 2019-07-25
  • ISBN : 9783527808649
GET THIS BOOKNeglected Tropical Diseases

A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors

Discovery and Development of Antidiabetic Agents from Natural Products

Discovery and Development of Antidiabetic Agents from Natural Products
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2016-10-11
  • ISBN : 9780128096925
GET THIS BOOKDiscovery and Development of Antidiabetic Agents from Natural Products

Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning

Drug Discovery for Leishmaniasis

Drug Discovery for Leishmaniasis
  • Author : Carmen Gil
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-11-02
  • ISBN : 9781782628897
GET THIS BOOKDrug Discovery for Leishmaniasis

Discovery and Development of Anti-Breast Cancer Agents from Natural Products

Discovery and Development of Anti-Breast Cancer Agents from Natural Products
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2021-06-24
  • ISBN : 9780128212783
GET THIS BOOKDiscovery and Development of Anti-Breast Cancer Agents from Natural Products

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Investing to Overcome the Global Impact of Neglected Tropical Diseases
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2015-08-05
  • ISBN : 9789241564861
GET THIS BOOKInvesting to Overcome the Global Impact of Neglected Tropical Diseases

This report repositions a group of 17 neglected tropical diseases on the global development agenda at a time of profound transitions in the economies of endemic countries and in thinking about the overarching objectives of development. In doing so it reinvigorates the drive to prevent control eliminate or eradicate diseases that blind maim and disfigure making life miserable for more than a billion people. Undetected and untreated several almost invariably kill. The burden of these diseases is further amplified by the

WIPO Re:Search: Advancing science for neglected tropical diseases, malaria and tuberculosis

WIPO Re:Search: Advancing science for neglected tropical diseases, malaria and tuberculosis
  • Author : World Intellectual Property Organization
  • Publisher : WIPO
  • Release Date : 2019-06-04
  • ISBN : 0987654321XXX
GET THIS BOOKWIPO Re:Search: Advancing science for neglected tropical diseases, malaria and tuberculosis

This edition of the Global Challenges In Focus series takes an in-depth look at some of WIPO Re:Search’s most promising scientific collaborations and their potential impacts – as described by the researchers and organizations involved.

Marine Natural Products

Marine Natural Products
  • Author : Hiromasa Kiyota
  • Publisher : Springer Nature
  • Release Date : 2021-09-02
  • ISBN : 9789811646379
GET THIS BOOKMarine Natural Products

This book is a compilation of the latest achievements of leading researchers in marine natural products with extremely diverse structures and biological activities. It presents discussions of isolation, structure elucidation, biosynthesis, total synthesis, and biochemical properties of the compounds with characteristic structures such as macrolides, cyclic depsipeptides, alkaloids, and water-soluble heterocyclic low-molecular-weight compounds, from sponges, bacteria, cyanobacteria, flagellates, and other such organisms. The book especially focuses on heterocyclic natural products as a title in the book series, Topics in Heterocyclic

Advances in Medicinal Chemistry Research

Advances in Medicinal Chemistry Research
  • Author : Edeildo Ferreira Da Silva, Jr.
  • Publisher : Unknown
  • Release Date : 2019-10-15
  • ISBN : 1536163686
GET THIS BOOKAdvances in Medicinal Chemistry Research

Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting

Rare Diseases and Orphan Products

Rare Diseases and Orphan Products
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
  • Publisher : National Academies Press
  • Release Date : 2011-04-03
  • ISBN : 9780309158060
GET THIS BOOKRare Diseases and Orphan Products

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.

Wound Healing Research

Wound Healing Research
  • Author : Prasun Kumar,Vijay Kothari
  • Publisher : Springer Nature
  • Release Date : 2021-07-20
  • ISBN : 9789811626777
GET THIS BOOKWound Healing Research

This book presents the latest knowledge on both the physiological and the microbiological aspects of wound healing. Fresh insights into the process of cutaneous wound healing are described, which involves tissue regeneration and repair processes consisting of a sequence of molecular and cellular events. The management of infected wounds is then discussed in detail, covering the roles of traditional medicine practices, novel anti-infective formulations, non-antibiotic approaches, and probiotic bacteria. A section devoted to the interdisciplinary approach to wound care addresses

Ethnomedicine: A Boon of Nature

Ethnomedicine: A Boon of Nature
  • Author : Dr. Keshamma E.,Narender Kumar
  • Publisher : Priya Lokare
  • Release Date : 2022-03-23
  • ISBN : 0987654321XXX
GET THIS BOOKEthnomedicine: A Boon of Nature

Ethnic medicine is the evaluation or combination of medicines common in the face of biologically active mixtures of plants and organisms. It is practiced by different ethnic groups, especially those who readily accept Western orders, such as B. Indigenous groups. These customs often collaborate with insects in Africa, America, or worldwide. The term folk medicine is sometimes used interchangeably with traditional medicine. Ethnomedical research is interdisciplinary; in its investigation of conventional prescriptions, it applies ethnobotany and clinical human studies strategies.

Discovery and Development of Drugs for Neglected Diseases: Chagas Disease, Human African Trypanosomiasis, and Leishmaniasis

Discovery and Development of Drugs for Neglected Diseases: Chagas Disease, Human African Trypanosomiasis, and Leishmaniasis
  • Author : Gildardo Rivera,Navin B. Patel,Debasish Bandyopadhyay
  • Publisher : Frontiers Media SA
  • Release Date : 2021-12-20
  • ISBN : 9782889717927
GET THIS BOOKDiscovery and Development of Drugs for Neglected Diseases: Chagas Disease, Human African Trypanosomiasis, and Leishmaniasis

Characterization of New Marine Secondary Metabolites for the Treatment of Cancer and Neglected Tropical Diseases

Characterization of New Marine Secondary Metabolites for the Treatment of Cancer and Neglected Tropical Diseases
  • Author : Thomas Luke Simmons
  • Publisher : Unknown
  • Release Date : 2008
  • ISBN : OCLC:192095604
GET THIS BOOKCharacterization of New Marine Secondary Metabolites for the Treatment of Cancer and Neglected Tropical Diseases

Small molecules from natural sources are vital to drug discovery by providing molecular diversity and novel chemical scaffolds for further pharmacological development. The emergence of multiple drug resistant pathogens and problems associated with natural product dereplication emphasize the continuing need for the discovery of new and relevant bioactive molecules for the treatment of human disease. This thesis describes the biological activity guided chemical investigation of several marine taxa with emphasis on the isolation and structure elucidation of new secondary metabolites

Drug Repurposing

Drug Repurposing
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-12-02
  • ISBN : 9781839685200
GET THIS BOOKDrug Repurposing

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to