Developmental and Fetal Origins of Differences in Monozygotic Twins

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  • Publisher : Academic Press
  • Release : 15 May 2020
  • ISBN : 9780128203071
  • Page : 386 pages
  • Rating : 4.5/5 from 103 voters

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Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis Features contributions from international experts in twin genetics and developmental biology

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Developmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins
  • Author : Alexandra Matias,Isaac Blickstein
  • Publisher : Academic Press
  • Release Date : 2020-05-15
  • ISBN : 9780128203071
GET THIS BOOKDevelopmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels,

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  • Publisher : Springer Nature
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  • Publisher : Rowman & Littlefield
  • Release Date : 2021-10-15
  • ISBN : 9781538132869
GET THIS BOOKDeliberately Divided

In Deliberately Divided, Nancy Segal revisits a controversial study that tracked the development of separated twins and triplets. None of the adoptive parents were told that they were raising a multiple birth baby. The truth was shocking for these parents and twins, many of whom have shared their unimaginable stories for the first time.

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  • Publisher : National Academies Press
  • Release Date : 2001-07-02
  • ISBN : 0309132975
GET THIS BOOKExploring the Biological Contributions to Human Health

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be

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  • Publisher : Springer
  • Release Date : 2019-03-28
  • ISBN : 9783030050757
GET THIS BOOKOld and New Perspectives on Mortality Forecasting

This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors. The key question in the book is whether it is possible

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  • Publisher : Academic Press
  • Release Date : 2021-08-27
  • ISBN : 9780128243268
GET THIS BOOKMedical Epigenetics

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate

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  • Publisher : National Academies Press
  • Release Date : 2015-07-23
  • ISBN : 9780309324885
GET THIS BOOKTransforming the Workforce for Children Birth Through Age 8

Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and

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  • Publisher : National Academies Press
  • Release Date : 2002-06-17
  • ISBN : 9780309076371
GET THIS BOOKScientific and Medical Aspects of Human Reproductive Cloning

Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in

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  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-02
  • ISBN : 9789400724952
GET THIS BOOKEpigenetic Epidemiology

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the

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  • Publisher : Springer
  • Release Date : 2017-03-15
  • ISBN : 9789811032332
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This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function

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  • Publisher : University of Adelaide Press
  • Release Date : 2015-10-08
  • ISBN : 9781925261158
GET THIS BOOKTwin Studies:

This volume is about an ongoing long-term research initiative led by researchers from the School of Dentistry at the University of Adelaide. The aim of this book is to provide an overview of the studies of the teeth and faces of Australian twins and their families that have extended over more than thirty years.

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  • Publisher : OUP Oxford
  • Release Date : 2009-04-02
  • ISBN : 9780191575228
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Family-based studies, including intergenerational, sibling, and twin studies, are increasingly being used to explore life course epidemiology. However, there are issues relating to study design and the statistical analysis of family-based studies that are still not well understood, and comprehending the underlying assumptions of these studies and drawing the inferences from them can be complex. This book provides the knowledge and skills required to design, analyse, and correctly interpret family-based studies. It explains what these studies can tell us about

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  • Release Date : 2012-09-10
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