Dendrimer Based Nanotherapeutics

Book Dendrimer Based Nanotherapeutics Cover

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  • Publisher : Academic Press
  • Release : 14 April 2021
  • ISBN : 9780128212516
  • Page : 484 pages
  • Rating : 4.5/5 from 103 voters

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Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher

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Dendrimer-Based Nanotherapeutics

Dendrimer-Based Nanotherapeutics
  • Author : Prashant Kesharwani
  • Publisher : Academic Press
  • Release Date : 2021-04-14
  • ISBN : 9780128212516
GET THIS BOOKDendrimer-Based Nanotherapeutics

Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related

Dendrimer Based Nanotherapeutics for Ocular Drug Delivery

Dendrimer Based Nanotherapeutics for Ocular Drug Delivery
  • Author : Siva Pramodh Kambhampati
  • Publisher : Unknown
  • Release Date : 2014
  • ISBN : OCLC:922892009
GET THIS BOOKDendrimer Based Nanotherapeutics for Ocular Drug Delivery

G4-OH was modified with linker having minimal amine groups and incorporation of TA as a nuclear localization enhancer resulted in compact gene vectors with favorable safety profile and achieved high levels of transgene expression in hard to transfect human retinal pigment epithelial cells (hRPE). Prepared dendrimer-gene complexes were non-toxic and achieved significant cell uptake and safe delivery of gene in to the nucleus. Further, polyethylene glycol (PEG) surface coating enhanced colloidal stability in physiological relevant solutions without affecting its

Combination Drug Delivery Approach as an Effective Therapy for Various Diseases

Combination Drug Delivery Approach as an Effective Therapy for Various Diseases
  • Author : Prashant Kesharwani
  • Publisher : Academic Press
  • Release Date : 2022-04-08
  • ISBN : 9780323858762
GET THIS BOOKCombination Drug Delivery Approach as an Effective Therapy for Various Diseases

Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a

Dendrimer-Based Drug Delivery Systems

Dendrimer-Based Drug Delivery Systems
  • Author : Yiyun Cheng
  • Publisher : John Wiley & Sons
  • Release Date : 2012-07-03
  • ISBN : 9780470460054
GET THIS BOOKDendrimer-Based Drug Delivery Systems

The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer

Pharmaceutical Applications of Dendrimers

Pharmaceutical Applications of Dendrimers
  • Author : Abhay Singh Chauhan,Hitesh Kulhari
  • Publisher : Elsevier
  • Release Date : 2019-11-15
  • ISBN : 9780128145289
GET THIS BOOKPharmaceutical Applications of Dendrimers

Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer
  • Author : Prashant Kesharwani
  • Publisher : Academic Press
  • Release Date : 2019-01-26
  • ISBN : 9780128163672
GET THIS BOOKNanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer

Aptamers Engineered Nanocarriers for Cancer Therapy

Aptamers Engineered Nanocarriers for Cancer Therapy
  • Author : Prashant Kesharwani
  • Publisher : Woodhead Publishing
  • Release Date : 2022-09-25
  • ISBN : 9780323855761
GET THIS BOOKAptamers Engineered Nanocarriers for Cancer Therapy

Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers – such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized

Nanotherapeutics

Nanotherapeutics
  • Author : Ezharul Hoque Chowdhury
  • Publisher : CRC Press
  • Release Date : 2016-04-21
  • ISBN : 9781498707527
GET THIS BOOKNanotherapeutics

The emergence of nanotherapeutics is attributable to the integration of nanotechnology, recombinant DNA technology, and synthetic organic chemistry with medicine for treating critical human diseases in a more efficient and specific molecular approach than therapy with conventionally-designed and formulated drugs. Nanotherapeutics: From Laboratory to Clinic comprehensively discusses the current shortcomings for delivery of classical (small) drugs, macromolecular therapeutics, and recombinant vaccine via the common intravascular and extravascular routes. The book describes the synthetic/chemical engineering methods as well as recombinant,

Design and Applications of Theranostic Nanomedicines

Design and Applications of Theranostic Nanomedicines
  • Author : Somasree Ray,Amit Kumar Nayak
  • Publisher : Woodhead Publishing
  • Release Date : 2022-09-10
  • ISBN : 9780323885980
GET THIS BOOKDesign and Applications of Theranostic Nanomedicines

Design and Applications of Theranostic Nanomedicines reviews the composition and design of various nanomedicines for theranostic applications, helping readers to make informed decisions when exploring novel treatments for disease. This book introduces readers to theranostic nanostructures as nanomedicines, beginning with a balanced look at the associated challenges, costs and benefits. The next section goes on to detail a range of different theranostic nanomedicines and their design, from nanodispersions and nanogels to exosomes and polymeric micelles. A variety of applications is

Nanotherapeutics in Cancer Vaccination and Challenges

Nanotherapeutics in Cancer Vaccination and Challenges
  • Author : Mahfoozur Rahman,Sarwar Beg,Waleed H. Almalki,Nabil A. Alhakamy,Hani Choudhry
  • Publisher : Academic Press
  • Release Date : 2022-03-03
  • ISBN : 9780128236871
GET THIS BOOKNanotherapeutics in Cancer Vaccination and Challenges

Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects.

Dendrimer-Based Nanomedicine

Dendrimer-Based Nanomedicine
  • Author : Istvan Majoros,James R. Baker, Jr.
  • Publisher : Pan Stanford Publishing
  • Release Date : 2008-05-31
  • ISBN : 9789814241045
GET THIS BOOKDendrimer-Based Nanomedicine

Examining free-shaped synthetic macromolecules, this guide reveals how dendrimers are used in a variety of scientific applications as a safer, more precise, and more effective way to practice medicine. This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, who are currently revolutionizing drug delivery techniques through the development of engineered nanodevices.

Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures
  • Author : Jaroslav Sebestik,Milan Reinis,Jan Jezek
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-13
  • ISBN : 9783709112069
GET THIS BOOKBiomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent

The Handbook of Nanomedicine

The Handbook of Nanomedicine
  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release Date : 2017-03-20
  • ISBN : 9781493969661
GET THIS BOOKThe Handbook of Nanomedicine

Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals

NanoOncology, An Issue of Clinics in Laboratory Medicine - E-Book

NanoOncology, An Issue of Clinics in Laboratory Medicine - E-Book
  • Author : Kewal Jain
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-03-26
  • ISBN : 9781455742899
GET THIS BOOKNanoOncology, An Issue of Clinics in Laboratory Medicine - E-Book

This issue of Clinics in Laboratory Medicine includes the following topics: Detection of cancer biomarkers by cerium oxide nanoparticles; Quantum dot-based assays for cancer biomarkers; Monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo diagnosis of cancer; RNA quantification with gold nanoprobes for cancer diagnostics; Nanostructured silica materials for imaging in cancer; and Nanoparticle-based cancer cell sorting.

Multifunctional Nanocarriers

Multifunctional Nanocarriers
  • Author : Neelesh Kumar Mehra,Saurabh Srivastava,Jitender Madan,Pankaj Kumar Singh
  • Publisher : Elsevier
  • Release Date : 2022-08-29
  • ISBN : 9780323852944
GET THIS BOOKMultifunctional Nanocarriers

Multifunctional Nanocarriers provides information on the concept, theory and application of multifunctional nanocarriers. The book covers current research, beginning with product strategy, targeted drug delivery, and advanced drug delivery approaches, along with numerous multifunctional nanocarriers and their regulatory considerations for product development. The book covers targeting, receptor mediated targeting, and recent advancements using multifunctional nanocarriers and their regulatory aspects. This is an important reference source for materials scientists and engineers who want to learn more about how multifunctional nanocarriers are