The Professional Guinea Pig

Book The Professional Guinea Pig Cover

Read or download book entitled The Professional Guinea Pig written by Roberto Abadie and published by Duke University Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that The Professional Guinea Pig book is available in the library.

  • Publisher : Duke University Press
  • Release : 30 July 2010
  • ISBN : 9780822393245
  • Page : 197 pages
  • Rating : 4.5/5 from 103 voters

Download The Professional Guinea Pig in PDF, Epub and Kindle

The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.

GET THIS BOOK

The Professional Guinea Pig

The Professional Guinea Pig
  • Author : Roberto Abadie
  • Publisher : Duke University Press
  • Release Date : 2010-07-30
  • ISBN : 9780822393245
GET THIS BOOKThe Professional Guinea Pig

The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition
  • Author : Allen Cato,Lynda Sutton,Allen Cato III
  • Publisher : CRC Press
  • Release Date : 2002-03-26
  • ISBN : 9780824744809
GET THIS BOOKClinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Aimed at those already involved in drug development or those considering entering the field, Clinical Drug Trials and Tribulations, Second Edition comprehensibly addresses the new, day-to-day challenges of drug development with valuable assessments of the areas affecting the conduction of nonclinical and clinical studies. Addressing which decisions should be made during drug development, this updated and expanded text/reference carefully guides readers through the various trials and tribulations that emerge phase-by-phase and are pertinent to all levels of pharmaceutical or

Clinical Trials in Psychiatry

Clinical Trials in Psychiatry
  • Author : Brian S. Everitt,Simon Wessely
  • Publisher : John Wiley & Sons
  • Release Date : 2008-04-15
  • ISBN : 047072384X
GET THIS BOOKClinical Trials in Psychiatry

At last – a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those seeking solutions to numerous problems relating to design, methodology and analysis of such trials. Practical examples and applications are used to ground theory whenever possible. The Second Edition includes new information regarding: Recent important psychiatric trials More specific discussion of psychiatry in the USA and the particular problems of trials

Novel Therapies in Head and Neck Cancer: Beyond the Horizon

Novel Therapies in Head and Neck Cancer: Beyond the Horizon
  • Author : Maie A. St. John,No hee Park
  • Publisher : Academic Press
  • Release Date : 2020-06-29
  • ISBN : 9780128209295
GET THIS BOOKNovel Therapies in Head and Neck Cancer: Beyond the Horizon

Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine

RANDOMIZED CONTROL TRIALS

RANDOMIZED CONTROL TRIALS
  • Author : BEDECARRATS ET AL.
  • Publisher : Unknown
  • Release Date : 2022-10-04
  • ISBN : 0191898260
GET THIS BOOKRANDOMIZED CONTROL TRIALS

Trials and Tribulations

Trials and Tribulations
  • Author : Scott D. Halpern
  • Publisher : Unknown
  • Release Date : 2002
  • ISBN : OCLC:244972852
GET THIS BOOKTrials and Tribulations

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition
  • Author : Allen Cato,Lynda Sutton,Allen Cato III
  • Publisher : CRC Press
  • Release Date : 2002-03-26
  • ISBN : 0824703146
GET THIS BOOKClinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Aimed at those already involved in drug development or those considering entering the field, Clinical Drug Trials and Tribulations, Second Edition comprehensibly addresses the new, day-to-day challenges of drug development with valuable assessments of the areas affecting the conduction of nonclinical and clinical studies. Addressing which decisions should be made during drug development, this updated and expanded text/reference carefully guides readers through the various trials and tribulations that emerge phase-by-phase and are pertinent to all levels of pharmaceutical or

Clinical Drug Trials and Tribulations

Clinical Drug Trials and Tribulations
  • Author : Allen E. Cato
  • Publisher : Marcel Dekker Incorporated
  • Release Date : 1988
  • ISBN : UOM:39015013228658
GET THIS BOOKClinical Drug Trials and Tribulations

A reference for pharmacologists, pharmacists, clinical chemists, drug regulators, and bioethicists, and a text for medical or pharmacy courses on drug development. The contributors address such topics as clinical drug development planning, causality in single-event drug reactions, pediatric drug tri

Her-2

Her-2
  • Author : Robert Bazell
  • Publisher : Random House
  • Release Date : 2011-04-27
  • ISBN : 9780307764980
GET THIS BOOKHer-2

Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation,

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Clinical Drug Trials and Tribulations, Revised and Expanded, Second Edition
  • Author : Allen Cato,Lynda Sutton,Allen Cato III
  • Publisher : CRC Press
  • Release Date : 2002-03-26
  • ISBN : 1135556733
GET THIS BOOKClinical Drug Trials and Tribulations, Revised and Expanded, Second Edition

Aimed at those already involved in drug development or those considering entering the field, Clinical Drug Trials and Tribulations, Second Edition comprehensibly addresses the new, day-to-day challenges of drug development with valuable assessments of the areas affecting the conduction of nonclinical and clinical studies. Addressing which decisions should be made during drug development, this updated and expanded text/reference carefully guides readers through the various trials and tribulations that emerge phase-by-phase and are pertinent to all levels of pharmaceutical or

Oncology Clinical Trials

Oncology Clinical Trials
  • Author : Susan Halabi, PhD,Wm. Kevin Kelly, DO
  • Publisher : Demos Medical Publishing
  • Release Date : 2009-12-22
  • ISBN : 1935281763
GET THIS BOOKOncology Clinical Trials

Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the marketplace, and expand the horizon of contemporary thinking about cancer biology. A poorly done trial does little to advance the field or guide clinical practice, consumes precious clinical and financial

Palliative Care, Trials and COVID-19 Tribulations

Palliative Care, Trials and COVID-19 Tribulations
  • Author : Cheng Hoon Chew,Yan Yee Yip,Syahirah Farhana Mohd Saleh,Khairul Nisa’ Ishak,Anis Suraya Muhamad Nawawai,Chun Keat Chew,Ting Soo Chow,Richard Boon Leong Lim,Bak Leong Goh,Pik Pin Goh,Kalaiarasu M. Peariasamy
  • Publisher : Institute for Clinical Research, NIH, Malaysia
  • Release Date : 2021-09-09
  • ISBN : 0987654321XXX
GET THIS BOOKPalliative Care, Trials and COVID-19 Tribulations

The COVID-19 pandemic started more than a year ago, but until today, we did not have a definitive cure for this disease. The SARS-CoV-2 virus constantly mutated over time, infecting more people and causing tremendous stress on the existing scarcity of healthcare resources all around the world. Here, the experts from ground zero will share their first-hand experience of clinical trials looking for a cure for COVID-19, like the WHO's Solidarity Trial and the role of palliative care in COVID-19

Field Trials of Health Interventions

Field Trials of Health Interventions
  • Author : Richard H. Morrow,David A. Ross
  • Publisher : Oxford University Press, USA
  • Release Date : 2015-06-11
  • ISBN : 9780198732860
GET THIS BOOKField Trials of Health Interventions

Before new interventions can be used in disease control programmes, it is essential that they are carefully evaluated in "field trials", which may be complex and expensive undertakings. Descriptions of the detailed procedures and methods used in trials that have been conducted in the past have generally not been published. As a consequence, those planning such trials have few guidelines available and little access to previously accumulated knowledge. In this book the practical issues of trial design and conduct are

Clinical Trials in Neurology

Clinical Trials in Neurology
  • Author : Bernard Ravina
  • Publisher : Cambridge University Press
  • Release Date : 2012-04-12
  • ISBN : 9780521762595
GET THIS BOOKClinical Trials in Neurology

Comprehensive book that suggests ways to improve the efficiency of clinical trials and the development of interventions in the neurosciences.

The Acid Room

The Acid Room
  • Author : Jesse Donaldson,Erika Dyck
  • Publisher : Unknown
  • Release Date : 2022-03-12
  • ISBN : 1772141860
GET THIS BOOKThe Acid Room

From the street, New Westminster's Hollywood Hospital didn't look like much - just a rambling white mansion, mostly obscured behind the holly trees from which it took its name. But, between 1957 and 1968, it was the site of more than 6000 supervised acid trips, as part of the burgeoning (and controversial) field of psychedelic psychiatry. Under the care of Medical Director J Ross MacLean, and ex-spy/researcher Al "Captain Trips" Hubbard, it became a mecca for alcoholics, anxiety patients, and unhappy couples (