Genome Editing in Cardiovascular and Metabolic Diseases

Book Genome Editing in Cardiovascular and Metabolic Diseases Cover

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  • Publisher : Springer
  • Release : 30 October 2022
  • ISBN : 9811956413
  • Page : 0 pages
  • Rating : 4.5/5 from 103 voters

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This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.

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Genome Editing in Cardiovascular and Metabolic Diseases

Genome Editing in Cardiovascular and Metabolic Diseases
  • Author : Junjie Xiao
  • Publisher : Springer
  • Release Date : 2022-10-30
  • ISBN : 9811956413
GET THIS BOOKGenome Editing in Cardiovascular and Metabolic Diseases

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in

Genome Editing

Genome Editing
  • Author : Kiran Musunuru
  • Publisher : Academic Press
  • Release Date : 2021-03-05
  • ISBN : 9780128236475
GET THIS BOOKGenome Editing

Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, this reference allows readers to get started and establish a full workflow from the beginning of the project to its full completion. With worked examples drawn from real-life experiments, as

Translational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine
  • Author : Annabelle Rodriguez-Oquendo
  • Publisher : Academic Press
  • Release Date : 2015-09-07
  • ISBN : 9780128004746
GET THIS BOOKTranslational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that

Human Genome Editing

Human Genome Editing
  • Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
  • Publisher : National Academies Press
  • Release Date : 2017-08-13
  • ISBN : 9780309452885
GET THIS BOOKHuman Genome Editing

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are

Cardiovascular Genomics

Cardiovascular Genomics
  • Author : Mohan K. Raizada,Julian F. R. Paton,Michael J. Katovich,Sergey Kasparov
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-02-24
  • ISBN : 9781592598830
GET THIS BOOKCardiovascular Genomics

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular

Cardiovascular Diseases

Cardiovascular Diseases
  • Author : Nikolaos Papageorgiou
  • Publisher : Academic Press
  • Release Date : 2016-08-05
  • ISBN : 9780128033135
GET THIS BOOKCardiovascular Diseases

Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared,

Cardiovascular Genetics and Genomics for the Cardiologist

Cardiovascular Genetics and Genomics for the Cardiologist
  • Author : Victor J. Dzau, MD,Choong-Chin Liew, PhD
  • Publisher : John Wiley & Sons
  • Release Date : 2008-04-15
  • ISBN : 9780470765944
GET THIS BOOKCardiovascular Genetics and Genomics for the Cardiologist

Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way

Genome Editing

Genome Editing
  • Author : Kursad Turksen
  • Publisher : Springer
  • Release Date : 2016-08-09
  • ISBN : 9783319341484
GET THIS BOOKGenome Editing

This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of

Human Flourishing in an Age of Gene Editing

Human Flourishing in an Age of Gene Editing
  • Author : Erik Parens,Josephine Johnston
  • Publisher : Oxford University Press
  • Release Date : 2019-07-29
  • ISBN : 9780190940386
GET THIS BOOKHuman Flourishing in an Age of Gene Editing

International uproar followed the recent announcement of the birth of twin girls whose genomes had been edited with a breakthrough DNA editing-technology. This technology, called clustered regularly interspaced short palindrome repeats or CRISPR-Cas9, can alter any DNA, including DNA in embryos, meaning that changes can be passed to the offspring of the person that embryo becomes. Should we use gene editing technologies to change ourselves, our children, and future generations to come? The potential uses of CRISPR-Cas9 and other gene

Genome Editing and Engineering

Genome Editing and Engineering
  • Author : Krishnarao Appasani
  • Publisher : Cambridge University Press
  • Release Date : 2018-08-23
  • ISBN : 9781107170377
GET THIS BOOKGenome Editing and Engineering

A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

Isogenic Human Pluripotent Stem Cell Models of Cardiovascular Disease-Associated Genetic Variation

Isogenic Human Pluripotent Stem Cell Models of Cardiovascular Disease-Associated Genetic Variation
  • Author : Derek Tilghman Peters
  • Publisher : Unknown
  • Release Date : 2016
  • ISBN : OCLC:995631144
GET THIS BOOKIsogenic Human Pluripotent Stem Cell Models of Cardiovascular Disease-Associated Genetic Variation

The properties of human pluripotent stem cells (hPSCs) make them uniquely suited to address this challenge - they retain a normal human genome in culture, can be genetically modified, and can be differentiated into multiple cell types. The work presented in this thesis demonstrates the use of hPSCs and genome editing technology to generate human disease models in vitro. We developed a genome editing system optimized for hPSCs that can be used to efficiently generate hPSC lines with targeted genetic

Using Single Cell Epigenomic Analysis to Reveal Mechanisms of Complex Disease

Using Single Cell Epigenomic Analysis to Reveal Mechanisms of Complex Disease
  • Author : James Hocker
  • Publisher : Unknown
  • Release Date : 2022
  • ISBN : OCLC:1336019938
GET THIS BOOKUsing Single Cell Epigenomic Analysis to Reveal Mechanisms of Complex Disease

Complex diseases, and cardiovascular diseases such as coronary artery disease, atrial fibrillation, and heart failure, are leading causes of morbidity and mortality worldwide. These diseases arise from interactions between lifestyle factors, environmental influences, and multiple disease associated genes. Efforts to identify the driving genes underlying complex diseases have culminated in genome-wide association studies (GWAS), which measure associations between common human sequence variants and disease phenotypes in large population cohorts. To date, GWAS have identified tens of thousands of sequence variants

Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy

Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2021-06-29
  • ISBN : 9780323853231
GET THIS BOOKReprogramming the Genome: CRISPR-Cas-based Human Disease Therapy

Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy, presents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 is a key technology for targeted genome editing and regulation in a number of organisms including mammalian cells. It is a rapid, simple, and cost-effective solution. CRISPR-Cas system has recently gained much scientific and public attention. This volume covers CRISPR-Cas9 based mammalian genome editing, creating disease models, cancer therapy, neurological, heredity, blood disorders, defective gene correction, stem cells therapy, epigenetic modifications, patents,

Precision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers
  • Author : Joel Faintuch,Salomao Faintuch
  • Publisher : Academic Press
  • Release Date : 2019-11-16
  • ISBN : 9780128191798
GET THIS BOOKPrecision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number

Genetic Cardiomyopathies

Genetic Cardiomyopathies
  • Author : Gianfranco Sinagra,Fulvio Camerini,Luisa Mestroni
  • Publisher : Springer
  • Release Date : 2012-10-17
  • ISBN : 884702756X
GET THIS BOOKGenetic Cardiomyopathies

In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the