Cancer Genomics

Book Cancer Genomics Cover

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  • Publisher : Academic Press
  • Release : 21 November 2013
  • ISBN : 9780123972743
  • Page : 510 pages
  • Rating : 4.5/5 from 103 voters

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Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment. Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics. Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.

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Cancer Genomics

Cancer Genomics
  • Author : Graham Dellaire,Jason N Berman,Robert J. Arceci
  • Publisher : Academic Press
  • Release Date : 2013-11-21
  • ISBN : 9780123972743
GET THIS BOOKCancer Genomics

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase

Cancer Genomics and Proteomics

Cancer Genomics and Proteomics
  • Author : Narendra Wajapeyee
  • Publisher : Humana Press
  • Release Date : 2016-09-17
  • ISBN : 1493946544
GET THIS BOOKCancer Genomics and Proteomics

Cancer Genomics and Proteomics: Methods and Protocols, Second Edition includes methods for the analyses of cancer genome and proteome that have illuminated us about the changes in cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Genomics and Proteomics: Methods and Protocols, Second Edition

Cancer Genomics for the Clinician

Cancer Genomics for the Clinician
  • Author : Ramaswamy Govindan, MD,Ashiq Masood, MD
  • Publisher : Springer Publishing Company
  • Release Date : 2019-01-28
  • ISBN : 9780826168689
GET THIS BOOKCancer Genomics for the Clinician

Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips

Cancer Genetics and Genomics for Personalized Medicine

Cancer Genetics and Genomics for Personalized Medicine
  • Author : Il-Jin Kim
  • Publisher : CRC Press
  • Release Date : 2017-04-11
  • ISBN : 9781315341101
GET THIS BOOKCancer Genetics and Genomics for Personalized Medicine

This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach? This lucid book helps undergraduate and graduate students, professional researchers, and clinicians to better understand the key concept of personalized medicine. The most up-to-date topics on personalized medicine in this book cover the recent trends in and

'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
  • Author : Nosheen Masood,Saima Shakil Malik
  • Publisher : Springer Nature
  • Release Date : 2020-03-20
  • ISBN : 9789811510670
GET THIS BOOK'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology

Collaborative Genomics Projects: A Comprehensive Guide

Collaborative Genomics Projects: A Comprehensive Guide
  • Author : Margi Sheth,Julia Zhang,Jean C Zenklusen
  • Publisher : Academic Press
  • Release Date : 2016-02-24
  • ISBN : 9780128023686
GET THIS BOOKCollaborative Genomics Projects: A Comprehensive Guide

Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a

Cancer Genomics and Proteomics

Cancer Genomics and Proteomics
  • Author : Paul B. Fisher
  • Publisher : Humana Press
  • Release Date : 2007-09-27
  • ISBN : 1588295044
GET THIS BOOKCancer Genomics and Proteomics

Cancer Genomics and Proteomics provides a compendium of techniques and applications in gene identification and function. The approaches described in detail are state-of-the art and can be tailored to individual ongoing or planned research projects. This volume is a valuable laboratory resource for designing experiments to identify and analyze genes that are relevant to complex biological phenomena.

Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing

Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing
  • Author : Khalid El Bairi
  • Publisher : Springer Nature
  • Release Date : 2020-09-28
  • ISBN : 9783030538217
GET THIS BOOKIlluminating Colorectal Cancer Genomics by Next-Generation Sequencing

This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the

The Genetics of Cancer

The Genetics of Cancer
  • Author : B.A. Ponder,M.J. Waring
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9789401106771
GET THIS BOOKThe Genetics of Cancer

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development.

Computational Genomics with R

Computational Genomics with R
  • Author : Altuna Akalin
  • Publisher : CRC Press
  • Release Date : 2020-12-16
  • ISBN : 9781498781862
GET THIS BOOKComputational Genomics with R

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the

Highlights of Progress in Research on Cancer

Highlights of Progress in Research on Cancer
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1957
  • ISBN : UCAL:B4264692
GET THIS BOOKHighlights of Progress in Research on Cancer

Understanding Genomic and Hereditary Cancer Risk

Understanding Genomic and Hereditary Cancer Risk
  • Author : Suzanne M. Mahon
  • Publisher : Unknown
  • Release Date : 2021
  • ISBN : 1635930499
GET THIS BOOKUnderstanding Genomic and Hereditary Cancer Risk

"Collecting a family medical history is a regular component of the nursing assessment process that often includes information on familial cancer diagnoses, and patients may fear that they or their loved ones might be at increased risk for developing cancer because of hereditary factors. Although true inherited risk for developing cancer is much less common than acquired risk for developing cancer, approximately 10% of cancer diagnoses can be attributed to inherited risk. The identification of families exhibiting hereditary cancer syndromes enables

Cancer Genomics

Cancer Genomics
  • Author : Ulrich Pfeffer
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-02-12
  • ISBN : 9789400758421
GET THIS BOOKCancer Genomics

The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely

Cancer Genomics

Cancer Genomics
  • Author : Michael Fraser,Alejandro Berlin,Veronique Ouellet,Fred Saad,Robert G. Bristow
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-21
  • ISBN : 9780128061114
GET THIS BOOKCancer Genomics

Prostate cancer (CaP) is the most commonly diagnosed malignancy in men in the Western world. In North America, more than 275000 men are diagnosed annually whereby approximately 1 in 6 men will be diagnosed with CaP in their lifetime, and 1 in 34 men will die from castrate-resistant metastatic disease. Unfortunately, current clinical prognostic factors explain only a proportion of the observed variation in clinical outcome from patient to patient. Furthermore, over-treatment of indolent and low-risk cancers leads to inappropriate morbidity following radiotherapy or surgery.

Cancer Genomics

Cancer Genomics
  • Author : Matthew Parker,Erin Hedlund,Jinghui Zhang
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-21
  • ISBN : 9780128061077
GET THIS BOOKCancer Genomics

The vast amount of genomic data being produced by the research community is becoming readily accessible to biomedical researchers and clinicians to apply to their cancer(s) of interest. The major cancer genome projects, among others, The Cancer Genome Atlas (TCGA), the International Cancer Genome Consortium (ICGC) and the Pediatric Cancer Genome Project (PCGP) are contributing to this genomic data goldmine by sequencing hundreds to thousands of cancer genomes and supplementing these data with analyses such as gene expression and