Bioreactor Modeling

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  • Publisher : Elsevier
  • Release : 06 October 2017
  • ISBN : 9780081011669
  • Page : 218 pages
  • Rating : 4.5/5 from 103 voters

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Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand, have the ability to modulate the rate of substrate assimilation. Moreover, the nature of the biochemical transformations results from a compromise between the needs of the cell and the available resources. This book revisits the modeling of bioreactors using a multi-scale approach. It addresses issues related to mixing, phase-to-phase transfers and the adaptation of microorganisms to variations in concentration, and explores the use of population balances for the simulation of bioreactors. By adopting a multidisciplinary perspective that draws on process engineering, fluid mechanics and microbiology, this book sheds new light on the particularity of bioprocesses in relation to physical and chemical phenomena. Presents a multiphase description of bioreactor modeling Includes a combination of concepts issued from different scientific fields to address a practical issue Provides a detailed description of the population balance concept as applied to biological systems Covers a set of illustrative examples of the interaction between hydrodynamics and biological response

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Bioreactor Modeling

Bioreactor Modeling
  • Author : Jerome Morchain
  • Publisher : Elsevier
  • Release Date : 2017-10-06
  • ISBN : 9780081011669
GET THIS BOOKBioreactor Modeling

Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand,

Solid-State Fermentation Bioreactors

Solid-State Fermentation Bioreactors
  • Author : David A. Mitchell,Nadia Krieger,Marin Berovic
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-08-02
  • ISBN : 9783540312864
GET THIS BOOKSolid-State Fermentation Bioreactors

This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer phenomena. The book includes case studies, and a review of practical issues involved in bioreactor performance.

Computational Modeling in Biomechanics

Computational Modeling in Biomechanics
  • Author : Suvranu De,Farshid Guilak,Mohammad Mofrad
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-03-10
  • ISBN : 9789048135752
GET THIS BOOKComputational Modeling in Biomechanics

Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ab initio quantum mechanical and molecular dynamics methods at the atomistic scales and the finite element, boundary element, meshfree as well as immersed boundary and lattice-Boltzmann methods at the continuum

Bioreactor Systems for Tissue Engineering

Bioreactor Systems for Tissue Engineering
  • Author : Cornelia Kasper,Martijn van Griensven,Ralf Pörtner
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-02-03
  • ISBN : 9783540693567
GET THIS BOOKBioreactor Systems for Tissue Engineering

The editors of this special volume would first like to thank all authors for their excellent contributions. We would also like to thank Prof. Dr. Thomas Scheper, Dr. Marion Hertel and Ulrike Kreusel for providing the opportunity to compose this volume and Springer for organizational and technical support. Tissue engineering represents one of the major emerging fields in modern b- technology; it combines different subjects ranging from biological and material sciences to engineering and clinical disciplines. The aim of tissue

Bioreactor System Design

Bioreactor System Design
  • Author : Juan A. Asenjo
  • Publisher : CRC Press
  • Release Date : 1994-11-17
  • ISBN : 0824790022
GET THIS BOOKBioreactor System Design

Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as strain and media selection, that have an overwhelming influence on all further operations, is emphasized.;This work is intended for biochemical, chemical and bioprocess engineers; biotechnologists; industrial biochemists; micro- and

An Introduction to Bioreactor Hydrodynamics and Gas-Liquid Mass Transfer

An Introduction to Bioreactor Hydrodynamics and Gas-Liquid Mass Transfer
  • Author : Enes Kadic,Theodore J. Heindel
  • Publisher : John Wiley & Sons
  • Release Date : 2014-03-14
  • ISBN : 9781118869833
GET THIS BOOKAn Introduction to Bioreactor Hydrodynamics and Gas-Liquid Mass Transfer

Reviews and compares the major types of bioreactors, defines their pros and cons, and identifies research needs and figures of merit that have yet to be addressed Describes common modes of operation in bioreactors Covers the three common bioreactor types, including stirred-tank bioreactors, bubble column bioreactors, and airlift bioreactors Details less common bioreactors types, including fixed bed bioreactors and novel bioreactor designs Discusses advantages and disadvantages of each bioreactor and provides a procedure for optimal bioreactor selection based on current

Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering
  • Author : Ashok Pandey,Ranjna Sirohi,Christian Larroche,Mohammad Taherzadeh
  • Publisher : Elsevier
  • Release Date : 2022-08-26
  • ISBN : 9780323984836
GET THIS BOOKCurrent Developments in Biotechnology and Bioengineering

Advances in Bioprocess Engineering, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a comprehensive overview of bioprocess systems, kinetics, bioreactor design, batch and continuous reactors and introduces key principles that enable bioprocess engineers to engage in analysis, optimization and design with consistent control over biological and chemical transformations. The bioprocessing sector is also updating its technologies with state-of-the art techniques to keep up with the rising demand of the industry and R&D. This book

Bioreactors

Bioreactors
  • Author : Goutam Saha,Alok Barua,Satyabroto Sinha
  • Publisher : CRC Press
  • Release Date : 2017-12-01
  • ISBN : 9781498736022
GET THIS BOOKBioreactors

Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to

Bioreactors

Bioreactors
  • Author : Carl-Fredrik Mandenius
  • Publisher : John Wiley & Sons
  • Release Date : 2016-02-16
  • ISBN : 9783527683376
GET THIS BOOKBioreactors

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production,

Biological Reaction Engineering

Biological Reaction Engineering
  • Author : Elmar Heinzle,Irving J. Dunn,John Ingham,Jiří E. Přenosil
  • Publisher : John Wiley & Sons
  • Release Date : 2021-07-06
  • ISBN : 9783527325245
GET THIS BOOKBiological Reaction Engineering

This practical book presents the modeling of dynamic biological engineering processes in a readily comprehensible manner, using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples illustrate almost every aspect of biological engineering science, with each one described in detail, including the model equations. The programs are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh

Comprehensive Biotechnology

Comprehensive Biotechnology
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2019-07-17
  • ISBN : 9780444640475
GET THIS BOOKComprehensive Biotechnology

Comprehensive Biotechnology, Third Edition unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of

The Prospect of Industry 5.0 in Biomanufacturing

The Prospect of Industry 5.0 in Biomanufacturing
  • Author : Pau Loke Show,Kit Wayne Chew,Tau Chuan Ling
  • Publisher : CRC Press
  • Release Date : 2021-07-02
  • ISBN : 9781000407419
GET THIS BOOKThe Prospect of Industry 5.0 in Biomanufacturing

This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it covers applications and challenges. FEATURES Describes the previous Industrial Revolution, current Industry 4.0, and how new technologies will transition toward Industry 5.0 Explains how Industry 5.0 can be applied in biomanufacturing Demonstrates new

Control in Bioprocessing

Control in Bioprocessing
  • Author : Pablo A. López Pérez,Ricardo Aguilar López,Ricardo Femat
  • Publisher : John Wiley & Sons
  • Release Date : 2020-03-10
  • ISBN : 9781119296324
GET THIS BOOKControl in Bioprocessing

Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation

Techno-economics and Life Cycle Assessment of Bioreactors

Techno-economics and Life Cycle Assessment of Bioreactors
  • Author : Puranjan Mishra,Lakhveer Singh,Pooja Ghosh
  • Publisher : Elsevier
  • Release Date : 2022-06-24
  • ISBN : 9780323885836
GET THIS BOOKTechno-economics and Life Cycle Assessment of Bioreactors

Techno-economics and Life Cycle Assessment of Bioreactors: Post-Covid19 Waste Management Approach covers the emerging trends in bioreactor research, including techno-economics and life cycle assessment perspectives, both key considerations in making the anaerobic-digestion process technically feasible, economically viable and environmentally sustainable. The book is divided into three sections, with an introductory chapter on the impact of COVID-19 on existing practices of waste and resource management. Sections cover advances in bioreactor development for enhanced valorization of waste, the techno-economics of the different

The Control Handbook (three volume set)

The Control Handbook (three volume set)
  • Author : William S. Levine
  • Publisher : CRC Press
  • Release Date : 2018-10-08
  • ISBN : 9781420073676
GET THIS BOOKThe Control Handbook (three volume set)

At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now, 15 years later, William Levine has once again compiled the most comprehensive and authoritative resource on control engineering. He has fully reorganized the text to reflect the technical advances achieved since the last edition and has expanded its contents to include the multidisciplinary perspective