Autophagy and Cardiometabolic Diseases

• Author : Jun Ren,James R. Sowers,Yingmei Zhang
• Publisher : Academic Press
• Release Date : 2018-04-12
• ISBN : 9780128054420

Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the

• Author : Jun Ren
• Publisher : Unknown
• Release Date : 2015
• ISBN : OCLC:903700615

• Author : Jun Ren,Xin Wang,Ying Mei Zhang
• Publisher : Frontiers Media SA
• Release Date : 2021-11-02
• ISBN : 9782889715831

• Author : Trent D. Evans
• Publisher : Unknown
• Release Date : 2019
• ISBN : OCLC:1140920983

The accumulation of dysfunctional proteins and organelles is a defining feature of metabolic disease in nearly every tissue. A key pathway addressing this challenge is the autophagy-lysosome system which serves to identify, sequester, and degrade cellular components. Here, I first report on harnessing TFEB, a transcription factor master regulator of genes involved in autophagy-lysosome biogenesis, lipid metabolism, and mitochondrial metabolism to drive this pathway in adipocytes. We found that TFEB overexpression protects mice from diet induced obesity and adverse metabolic

• Author : H. Böhles,A. C. Sewell
• Publisher : CRC Press
• Release Date : 2004
• ISBN : 3887631048

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with

• Author : Ning Chen
• Publisher : Springer Nature
• Release Date : 2022-06-29
• ISBN : 9789811645259

• Author : Weidong Le
• Publisher : Springer Nature
• Release Date : 2020-07-15
• ISBN : 9789811542725

This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is

• Author : Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
• Publisher : Frontiers Media SA
• Release Date : 2019-08-08
• ISBN : 9782889459384

• Author : Paul Holvoet
• Publisher : Springer Nature
• Release Date : 2021-03-26
• ISBN : 9783030688448

This book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a

• Author : Anonim
• Publisher : Unknown
• Release Date : 2014
• ISBN : OCLC:889882310

Cardiovascular diseases (CVD) are the leading cause of mortality worldwide. Approximately 17 million people die of CVD. Obesity is considered to be a major risk factor which predisposes an individual to an increased risk of cardiovascular disease mortality. A clustering of risk factors such as obesity, insulin resistance and dyslipidemia results in the metabolic syndrome (MetS) which has a high prevalence rate of 23.7 percent of the US population. Several studies have shown that cellular autophagy is altered in the setting of

• Author : Joilson O. Martins,William T. Festuccia,Karen Yvonne Stokes,Stephen Fernandes Rodrigues
• Publisher : Frontiers Media SA
• Release Date : 2021-12-01
• ISBN : 9782889717477

• Author : Beverly Rothermel,Abhinav Diwan
• Publisher : Elsevier
• Release Date : 2021-09-22
• ISBN : 9780128220047

Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory

• Author : Lorrie A. Kirshenbaum
• Publisher : Springer Nature
• Release Date : 2022-06-29
• ISBN : 9783030787998

• Author : Dr Leonard Cain
• Publisher : Independently Published
• Release Date : 2019-12-03
• ISBN : 1671220293

Have you been trying to slim down unsuccessfully? Have you starved for days and weeks, only to regain all of the weight with crash dieting? If this is true, "Intermittent Fasting to Unlock Hidden Potentials" is the right book for you! In this book, you will learn: What is intermittent fasting; How to use it to your advantage; Why you're failing to lose weight despite doing the best you can to eat healthily; What are the true healing capacities of

• Author : Omar Mascarena
• Publisher : Unknown
• Release Date : 2021-05-17
• ISBN : 9798506024156

Harness the health benefits of intermittent fasting--a comprehensive guide with meal plans and more Intermittent fasting (IF) is an evidence-based eating program that's existed in multiple forms for nearly 2,500 years, with roots in evolution and religion. That said, there are many ways to approach it and apply it to your life. This book is filled with essential information, how-to advice, FAQs, meal plans, and recipes to help you adopt and maintain an intermittent fasting lifestyle for weight loss and improved