Autophagy and Cardiometabolic Diseases
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- Author : Jun Ren
- Publisher : Academic Press
- Release : 12 April 2018
- ISBN : 9780128054420
- Page : 340 pages
- Rating : 4.5/5 from 103 voters
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Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases Provides knowledge from internationally recognized contributors in the field Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases Contains access to a companion website with additional illustrations
Autophagy and Cardiometabolic Diseases
- Author : Jun Ren,James R. Sowers,Yingmei Zhang
- Publisher : Academic Press
- Release Date : 2018-04-12
- ISBN : 9780128054420
Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the
Autophagy and Protein Quality Control in Cardiometabolic Diseases

- Author : Jun Ren
- Publisher : Unknown
- Release Date : 2015
- ISBN : OCLC:903700615
New Drug Targets for Proteotoxicity in Cardiometabolic Diseases
- Author : Jun Ren,Xin Wang,Ying Mei Zhang
- Publisher : Frontiers Media SA
- Release Date : 2021-11-02
- ISBN : 9782889715831
The Autophagy-lysosome System in Cardiometabolic Disease

- Author : Trent D. Evans
- Publisher : Unknown
- Release Date : 2019
- ISBN : OCLC:1140920983
The accumulation of dysfunctional proteins and organelles is a defining feature of metabolic disease in nearly every tissue. A key pathway addressing this challenge is the autophagy-lysosome system which serves to identify, sequester, and degrade cellular components. Here, I first report on harnessing TFEB, a transcription factor master regulator of genes involved in autophagy-lysosome biogenesis, lipid metabolism, and mitochondrial metabolism to drive this pathway in adipocytes. We found that TFEB overexpression protects mice from diet induced obesity and adverse metabolic
Metabolic Cardiomyopathy
- Author : H. Böhles,A. C. Sewell
- Publisher : CRC Press
- Release Date : 2004
- ISBN : 3887631048
During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with
Exercise, Autophagy and Chronic Diseases
- Author : Ning Chen
- Publisher : Springer Nature
- Release Date : 2022-06-29
- ISBN : 9789811645259
Autophagy: Biology and Diseases
- Author : Weidong Le
- Publisher : Springer Nature
- Release Date : 2020-07-15
- ISBN : 9789811542725
This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is
Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease
- Author : Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
- Publisher : Frontiers Media SA
- Release Date : 2019-08-08
- ISBN : 9782889459384
Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer
- Author : Paul Holvoet
- Publisher : Springer Nature
- Release Date : 2021-03-26
- ISBN : 9783030688448
This book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a
Characterization of Cardiac Autophagy in the Setting of Metabolic Syndrome Using Animal Models

- Author : Anonim
- Publisher : Unknown
- Release Date : 2014
- ISBN : OCLC:889882310
Cardiovascular diseases (CVD) are the leading cause of mortality worldwide. Approximately 17 million people die of CVD. Obesity is considered to be a major risk factor which predisposes an individual to an increased risk of cardiovascular disease mortality. A clustering of risk factors such as obesity, insulin resistance and dyslipidemia results in the metabolic syndrome (MetS) which has a high prevalence rate of 23.7 percent of the US population. Several studies have shown that cellular autophagy is altered in the setting of
Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges
- Author : Joilson O. Martins,William T. Festuccia,Karen Yvonne Stokes,Stephen Fernandes Rodrigues
- Publisher : Frontiers Media SA
- Release Date : 2021-12-01
- ISBN : 9782889717477
Autophagy in Health and Disease
- Author : Beverly Rothermel,Abhinav Diwan
- Publisher : Elsevier
- Release Date : 2021-09-22
- ISBN : 9780128220047
Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory
Biochemistry of Apoptosis and Autophagy
- Author : Lorrie A. Kirshenbaum
- Publisher : Springer Nature
- Release Date : 2022-06-29
- ISBN : 9783030787998
Intermittent Fasting to Unlock Hidden Potentials
- Author : Dr Leonard Cain
- Publisher : Independently Published
- Release Date : 2019-12-03
- ISBN : 1671220293
Have you been trying to slim down unsuccessfully? Have you starved for days and weeks, only to regain all of the weight with crash dieting? If this is true, "Intermittent Fasting to Unlock Hidden Potentials" is the right book for you! In this book, you will learn: What is intermittent fasting; How to use it to your advantage; Why you're failing to lose weight despite doing the best you can to eat healthily; What are the true healing capacities of
Intermittent Fasting And Weight Loss
- Author : Omar Mascarena
- Publisher : Unknown
- Release Date : 2021-05-17
- ISBN : 9798506024156
Harness the health benefits of intermittent fasting--a comprehensive guide with meal plans and more Intermittent fasting (IF) is an evidence-based eating program that's existed in multiple forms for nearly 2,500 years, with roots in evolution and religion. That said, there are many ways to approach it and apply it to your life. This book is filled with essential information, how-to advice, FAQs, meal plans, and recipes to help you adopt and maintain an intermittent fasting lifestyle for weight loss and improved