Artemisinin Based and Other Antimalarials

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  • Publisher : Academic Press
  • Release : 28 November 2017
  • ISBN : 9780128132111
  • Page : 736 pages
  • Rating : 4.5/5 from 103 voters

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Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

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Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
  • Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
  • Publisher : Academic Press
  • Release Date : 2017-11-28
  • ISBN : 9780128132111
GET THIS BOOKArtemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable

Saving Lives, Buying Time

Saving Lives, Buying Time
  • Author : Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
  • Publisher : National Academies Press
  • Release Date : 2004-10-09
  • ISBN : 9780309092180
GET THIS BOOKSaving Lives, Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a

Antimalarial Chemotherapy

Antimalarial Chemotherapy
  • Author : Philip J. Rosenthal
  • Publisher : Springer Science & Business Media
  • Release Date : 2001-04-01
  • ISBN : 9781592591114
GET THIS BOOKAntimalarial Chemotherapy

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy:

Treatment and Prevention of Malaria

Treatment and Prevention of Malaria
  • Author : Henry M. Staines,Sanjeev Krishna
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-06
  • ISBN : 9783034604796
GET THIS BOOKTreatment and Prevention of Malaria

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the

Malaria Control During Mass Population Movements and Natural Disasters

Malaria Control During Mass Population Movements and Natural Disasters
  • Author : Program on Forced Migration and Health at the Mailman School of Public Health of Columbia University,National Research Council,Committee on Population,Roundtable on the Demography of Forced Migration,Holly A. Williams,Peter B. Bloland
  • Publisher : National Academies Press
  • Release Date : 2003-01-16
  • ISBN : 9780309086158
GET THIS BOOKMalaria Control During Mass Population Movements and Natural Disasters

Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of Columbia University have commissioned a series of epidemiological reviews on priority public health problems for forced migrants that will update the state of knowledge. Malaria Control During Mass Population Movements

Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy
  • Author : Qigui Li,Mark R. Hickman
  • Publisher : Bentham Science Publishers
  • Release Date : 2015-06-04
  • ISBN : 9781681080543
GET THIS BOOKPharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Malaria takes a great toll on human health and well-being, particularly in tropical regions including Sub-Saharan Africa, Southeast Asia, Oceania and parts of the Americas. In recent years, some Plasmodium strains have become increasingly resistant to all classes of conventional antimalarial drugs currently in use. Researchers have, therefore, stepped up efforts to revise atimalarial drug policies, develop new drugs, and implement new strategies to combat this disease. In order to prevent widespread resistance, antimalarial combination therapies (ACTs) have been deployed

Guidelines for the Treatment of Malaria. Third Edition

Guidelines for the Treatment of Malaria. Third Edition
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2015-08-13
  • ISBN : 9789241549127
GET THIS BOOKGuidelines for the Treatment of Malaria. Third Edition

Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all

Artemisinin-based and Other Antimalarials

Artemisinin-based and Other Antimalarials
  • Author : Keith Arnold,Muoi Arnold,Meiyi Zeng
  • Publisher : Unknown
  • Release Date : 2018
  • ISBN : 7030570413
GET THIS BOOKArtemisinin-based and Other Antimalarials

Antimalarial Agents

Antimalarial Agents
  • Author : Graham L. Patrick
  • Publisher : Elsevier
  • Release Date : 2020-05-30
  • ISBN : 9780081012413
GET THIS BOOKAntimalarial Agents

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work towards antimalarial solution, providing practical guidance on current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over the last decade have seen vast improvements in the effectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs

Antimalarial Natural Products

Antimalarial Natural Products
  • Author : A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Yoshinori Asakawa,Ji-Kai Liu,Verena M. Dirsch
  • Publisher : Springer
  • Release Date : 2022-01-04
  • ISBN : 3030898725
GET THIS BOOKAntimalarial Natural Products

This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries

Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2010
  • ISBN : 9789241547925
GET THIS BOOKGuidelines for the Treatment of Malaria

"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Current Topics in Malaria

Current Topics in Malaria
  • Author : Alfonso J. Rodriguez-Morales
  • Publisher : Unknown
  • Release Date : 2016-11-30
  • ISBN : 9789535127895
GET THIS BOOKCurrent Topics in Malaria

Artemisia annua - Pharmacology and Biotechnology

Artemisia annua - Pharmacology and Biotechnology
  • Author : Tariq Aftab,Jorge F.S. Ferreira,M. Masroor A. Khan,M. Naeem
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-26
  • ISBN : 9783642410277
GET THIS BOOKArtemisia annua - Pharmacology and Biotechnology

Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A.

CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel
  • Author : Centers for Disease Control and Prevention CDC
  • Publisher : Oxford University Press
  • Release Date : 2017-04-17
  • ISBN : 9780190628635
GET THIS BOOKCDC Yellow Book 2018: Health Information for International Travel

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the

Biomedical Applications of Metals

Biomedical Applications of Metals
  • Author : Mahendra Rai,Avinash P. Ingle,Serenella Medici
  • Publisher : Springer
  • Release Date : 2018-02-24
  • ISBN : 9783319748146
GET THIS BOOKBiomedical Applications of Metals

Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the