Antimicrobial Peptides in Gastrointestinal Diseases

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  • Publisher : Academic Press
  • Release : 06 June 2018
  • ISBN : 9780128143209
  • Page : 186 pages
  • Rating : 4.5/5 from 103 voters

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Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application

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Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release Date : 2018-06-06
  • ISBN : 9780128143209
GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only

Intestinal Immune System

Intestinal Immune System
  • Author : Soichiro Miura,Ryota Hokari
  • Publisher : Biota Publishing
  • Release Date : 2011-08-01
  • ISBN : 9781615041459
GET THIS BOOKIntestinal Immune System

In the intestine, a unique immunological system that is different from the systemic immune system exists to provide adaptive immunity in response to luminal bacteria and dietary antigens. There are many lymphoid cell aggregates called gut-associated lymphoid tissue (GALT) including Peyer’s patches (PPs), which function as important induction sites for the mucosal immune response. M-cells are present in the epithelium of PPs, having a specialized structure for uptake of macromolecules such as bacteria. In addition to GALT, there are

Lasso Peptides

Lasso Peptides
  • Author : Yanyan Li,Séverine Zirah,Sylvie Rebuffat
  • Publisher : Springer
  • Release Date : 2014-10-21
  • ISBN : 9781493910106
GET THIS BOOKLasso Peptides

Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located

Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
  • Author : Daniel C. Baumgart
  • Publisher : Springer
  • Release Date : 2017-03-01
  • ISBN : 9783319337036
GET THIS BOOKCrohn's Disease and Ulcerative Colitis

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
  • Author : Anton Ficai,Alexandru Mihai Grumezescu
  • Publisher : Elsevier
  • Release Date : 2017-05-29
  • ISBN : 9780323461511
GET THIS BOOKNanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials,

Lessons in Immunity

Lessons in Immunity
  • Author : Loriano Ballarin,Matteo Cammarata
  • Publisher : Academic Press
  • Release Date : 2016-04-08
  • ISBN : 9780128032534
GET THIS BOOKLessons in Immunity

Lessons in Immunity: From Single-cell Organisms to Mammals stems from the activity of the Italian Association of Developmental and Comparative Immunobiology (IADCI), represented by the editors. This book is presented as a series of short overviews that report on the current state of various relevant fields of immunobiology from an evolutionary perspective. The overviews are written by authors directly involved in the research, and most are members of the IADCI or have otherwise been involved in the related research for

New Weapons to Control Bacterial Growth

New Weapons to Control Bacterial Growth
  • Author : Tomas G. Villa,Miguel Vinas
  • Publisher : Springer
  • Release Date : 2016-03-24
  • ISBN : 9783319283685
GET THIS BOOKNew Weapons to Control Bacterial Growth

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages

Antimicrobial Peptides and Human Disease

Antimicrobial Peptides and Human Disease
  • Author : William Shafer
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-10-05
  • ISBN : 9783540299165
GET THIS BOOKAntimicrobial Peptides and Human Disease

Microbes are in our midst soon after birth. Thankfully, the number of harmless (and often beneficial) microbes far outnumber those that would do us harm. Our ability to ward-off pathogens in our environment, including those that can colonize our exterior and/or interior surfaces, depends on the integrative action of the innate and adaptive immunity systems. This volume of CTMI, entitled Antimicrobial Peptides and Human Disease, is dedicated to the role of antimicrobial peptides (AMPs) in the innate host defense

Antimicrobial Peptides and Innate Immunity

Antimicrobial Peptides and Innate Immunity
  • Author : Pieter S. Hiemstra,Sebastian A. J. Zaat
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-02-01
  • ISBN : 9783034805414
GET THIS BOOKAntimicrobial Peptides and Innate Immunity

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. his book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-12-26
  • ISBN : 9781481603072
GET THIS BOOKAntimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Antimicrobial Cationic Peptides. The editors have built Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antimicrobial Cationic Peptides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antimicrobial Cationic

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Katsumi Matsuzaki
  • Publisher : Springer
  • Release Date : 2019-04-12
  • ISBN : 9789811335884
GET THIS BOOKAntimicrobial Peptides

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3),

Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond

Advances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond
  • Author : Mark Hulett,Charles Lee Bevins,Thanh Kha Phan
  • Publisher : Frontiers Media SA
  • Release Date : 2021-04-07
  • ISBN : 9782889666676
GET THIS BOOKAdvances in The Immunology of Host Defense Peptide: Mechanisms and Applications of Antimicrobial Functions and Beyond

Health and the Gut

Health and the Gut
  • Author : William Olds
  • Publisher : CRC Press
  • Release Date : 2014-08-04
  • ISBN : 9781498701266
GET THIS BOOKHealth and the Gut

This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut—the gut microbiome—is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: • Gut microbiome’s roles in the pathogenesis of obesity and autoimmune disease • The effect of nutrition on the richness of

Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release Date : 2005-09-29
  • ISBN : 9781420028836
GET THIS BOOKNutraceutical Proteins and Peptides in Health and Disease

Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern

Gut Peptides

Gut Peptides
  • Author : John H. Walsh,G. J. Dockray
  • Publisher : Raven Press (ID)
  • Release Date : 1994
  • ISBN : UOM:39015032878392
GET THIS BOOKGut Peptides

Provides a comprehensive approach to gastrointestinal hormones, for clinicians and scientists who are interested in hormonal regulation of the gastrointestinal tract. The first section discusses general issues related to peptides as messengers, including receptors and signal transduction and control of gene expression. The second section presents the biochemical and physiological features of the gastrointestinal hormones and neuropeptides. The third section integrates these peptides into physiological and pathophysiological regulatory pathways of the gut. Annotation copyright by Book News, Inc., Portland, OR