Animal Models for the Study of Human Disease

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  • Publisher : Academic Press
  • Release : 29 May 2013
  • ISBN : 9780124159129
  • Page : 1108 pages
  • Rating : 5/5 from 1 voters

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Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

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Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease
  • Author : P. Michael Conn
  • Publisher : Academic Press
  • Release Date : 2013-05-29
  • ISBN : 9780124159129
GET THIS BOOKAnimal Models for the Study of Human Disease

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders,

Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease
  • Author : P. Michael Conn
  • Publisher : Academic Press
  • Release Date : 2013
  • ISBN : 0124158943
GET THIS BOOKAnimal Models for the Study of Human Disease

Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders,

Experimental Animal Models of Human Diseases

Experimental Animal Models of Human Diseases
  • Author : Bartholomew Ibeh
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-05-23
  • ISBN : 9781789231649
GET THIS BOOKExperimental Animal Models of Human Diseases

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine
  • Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use
  • Publisher : National Academies Press
  • Release Date : 2018-05-29
  • ISBN : 9780309471190
GET THIS BOOKAdvancing Disease Modeling in Animal-Based Research in Support of Precision Medicine

Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed

Mouse Cell Culture

Mouse Cell Culture
  • Author : Ivan Bertoncello
  • Publisher : Unknown
  • Release Date : 2019
  • ISBN : 1493990861
GET THIS BOOKMouse Cell Culture

Autoimmune Disease Models

Autoimmune Disease Models
  • Author : Irun R. Cohen,Ariel Miller
  • Publisher : Academic Press
  • Release Date : 2014-06-28
  • ISBN : 9780080917368
GET THIS BOOKAutoimmune Disease Models

Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
  • Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
  • Publisher : National Academies Press
  • Release Date : 1988-02-01
  • ISBN : 9780309038393
GET THIS BOOKUse of Laboratory Animals in Biomedical and Behavioral Research

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of

Rabbit Biotechnology

Rabbit Biotechnology
  • Author : Louis-Marie Houdebine,Jianglin Fan
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-04-24
  • ISBN : 9789048122271
GET THIS BOOKRabbit Biotechnology

Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
  • Author : P. Michael Conn
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-03-07
  • ISBN : 9781597452854
GET THIS BOOKSourcebook of Models for Biomedical Research

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

The Alchemy of Disease

The Alchemy of Disease
  • Author : John Whysner
  • Publisher : Columbia University Press
  • Release Date : 2020-06-02
  • ISBN : 9780231549509
GET THIS BOOKThe Alchemy of Disease

Since the dawn of the industrial age, we have unleashed a bewildering number of potentially harmful chemicals. But out of this vast array, how do we identify the actual threats? What does it take to prove that a certain chemical causes cancer? How do we translate academic knowledge of the toxic effects of particular substances into understanding real-world health consequences? The science that answers these questions is toxicology. In The Alchemy of Disease, John Whysner offers an accessible and compelling

Cellular and Animal Models in Human Genomics Research

Cellular and Animal Models in Human Genomics Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-07-30
  • ISBN : 9780128165744
GET THIS BOOKCellular and Animal Models in Human Genomics Research

Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic

Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents
  • Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Board on Life Sciences,Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents
  • Publisher : National Academies Press
  • Release Date : 2006-09-07
  • ISBN : 9780309102117
GET THIS BOOKOvercoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease
  • Author : P. Michael Conn
  • Publisher : Academic Press
  • Release Date : 2017-06-08
  • ISBN : 0128094680
GET THIS BOOKAnimal Models for the Study of Human Disease

Animal Models for the Study of Human Disease, Second Edition provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease. Organized by disease orientation for ease of searchability Provides information

Modeling Neuropsychiatric Disorders in Laboratory Animals

Modeling Neuropsychiatric Disorders in Laboratory Animals
  • Author : Kurt Leroy Hoffman
  • Publisher : Woodhead Publishing
  • Release Date : 2015-08-28
  • ISBN : 9780081001066
GET THIS BOOKModeling Neuropsychiatric Disorders in Laboratory Animals

Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the

Animal Models for Neurodegenerative Disease

Animal Models for Neurodegenerative Disease
  • Author : Jesus Avila,Jose J. Lucas,Felix Hernandez
  • Publisher : Royal Society of Chemistry
  • Release Date : 2011
  • ISBN : 9781849731843
GET THIS BOOKAnimal Models for Neurodegenerative Disease

This book provides up-to-date information on the use of transgenic mouse models in the study of neurodegenerative disorders. The editors have extensive knowledge and experience in this field and the book is aimed at undergraduates, postgraduates and academics.