Alzheimer s Disease Theranostics
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- Author : Magisetty Obulesu
- Publisher : Academic Press
- Release : 20 January 2019
- ISBN : 9780128167397
- Page : 80 pages
- Rating : 4.5/5 from 103 voters
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Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders such as Alzheimer’s disease. Manifold theranostic maneuvers include antioxidants, natural bioactive compounds, gene therapy, and nanotechnological approaches, all of which are discussed in this important work. Examines various theranostic applications for the diagnosis and treatment of Alzheimer’s disease Features a comprehensive overview of nanoparticle therapeutics in the area and use of antioxidants Assesses the common challenges and lessons learned from blood-brain barrier challenges, viral vector approaches and mitochondria-targeted therapeutics
Alzheimer’s Disease Theranostics
- Author : Magisetty Obulesu
- Publisher : Academic Press
- Release Date : 2019-01-20
- ISBN : 9780128167397
Alzheimer’s Disease Theranostics discusses the latest information on recent theranostic avenues for both the diagnosis and treatment of Alzheimer’s patients. It presents the pros and cons of the probable mechanistic role of nanoparticles in crossing the blood-brain barrier and improving disease symptoms. Finally, it highlights the merits of existing maneuvers and suggests perspectives to aid in future developments. Despite the difficulty of drug delivery to the brain, there are some nanoparticulate platforms demonstrating promise in treating neurodegenerative disorders
Adverse Effects of Engineered Nanomaterials
- Author : Bengt Fadeel,Antonio Pietroiusti,Anna A. Shvedova
- Publisher : Academic Press
- Release Date : 2012
- ISBN : 9780123869401
An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety. Multi-authored book written by leading US and European experts on nanotoxicology and nanomedicine Discusses the health implications and a clinical translation of experimental data in this area Takes a schematic, non-exhaustive approach to summarize the most important research data in this field Includes a glossary, with a brief explanation of the
The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging
- Author : Andre S. Merbach
- Publisher : John Wiley & Sons
- Release Date : 2013-04-15
- ISBN : 9781119991762
"The second edition of The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treaty covering all aspects of production, use, operating mechanism and theory of these diagnostic agents used to produce high contrast images in MRI..It has been completed to now include recent developments on "classical" Gd-based and iron-oxide probes and chapters dedicated to the most significant advances in molecular imaging probes. Chemical Exchange Saturation Transfer is discussed, which is a novel means of generating
Personalized Medicine (beyond PET Biomarkers)
- Author : Sushil Sharma (Ph. D., D.M.R.I.T.)
- Publisher : Nova Biomedical Books
- Release Date : 2016
- ISBN : 1634853334
Nova Science Publishers, New York, U.S.A has now released Personalized Medicine (Beyond PET Biomarkers), which is an extension of the author''s recently published book Progress in PET Radiopharmaceuticals: Quality Control and Theranostics. In addition to recently-developed clinically-significant PET-RPs as biomarkers, this book describes various other emerging biotechnologies including: genomic medicine, nanotechnology, novel molecular biomarkers, and noninvasive imaging biotechnologies for early theranostics and personalized patient care, with minimum or no adverse effects. New therapeutic interventions including gene and cell
Expediting the Discovery and Potential Translation of Theranostic Agents for Alzheimer's Disease

- Author : Richard Anthony McClure
- Publisher : Unknown
- Release Date : 2015
- ISBN : OCLC:1104539539
Nanotheranostics
- Author : Mahendra Rai,Bushra Jamil
- Publisher : Springer Nature
- Release Date : 2019-11-22
- ISBN : 9783030297688
This book is specifically designed to provide information about various nanocarriers currently developed under the emerging field of nanotheranostics for a sustained, controlled, and targeted co-delivery of diagnostic and therapeutic agents. Diverse theranostic applications of nanotechnology and their limitations are also addressed. It integrates nanobiotechnology with theranostic applications. The combined term nanotheranostics has diverse application particularly in chemotherapy and other infectious diseases.Among other topics addressed are antimicrobial resistance, targeting intra-cellular pathogens, viruses and bacteria, chemotherapy, cancer therapeutics, and inflammatory
Charnolophagy in Health and Disease
- Author : Sushil Sharma
- Publisher : CRC Press
- Release Date : 2021-09-03
- ISBN : 9781000298451
This book introduces charnolophagy (CP) as energy-driven, lysosomal-dependent mitochondrial inclusion-specific pleomorphic Charnoly body (CB) autophagy (ATG) involving free radical-induced Ca2+ dyshomeostasis, ΔΨ collapse, and ATP depletion in congenital diseases, pressure ulcers, metabolic diseases, hepatic diseases, diabetes, obesity, inflammatory diseases, musculoskeletal diseases, sarcopenia, cachexia, respiratory diseases, gastrointestinal diseases, hyperlipidemia, skin and hair diseases, pulmonary diseases, cardiovascular diseases, renal diseases, sepsis-induced multi-organ failure, reproductive diseases, inflammatory diseases, ophthalmic diseases, neurodegenerative diseases, drug addiction, aging, microbial (including COVID-19) infections, and belligerent malignancies implicated in
Nanobiotechnology in Diagnosis, Drug Delivery and Treatment
- Author : Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
- Publisher : John Wiley & Sons
- Release Date : 2020-11-17
- ISBN : 9781119671862
Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It
Nanobiotechnology in Diagnosis, Drug Delivery and Treatment
- Author : Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
- Publisher : John Wiley & Sons
- Release Date : 2020-12-02
- ISBN : 9781119671770
Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It
Functionalized Nanocarriers for Theranostics
- Author : Stefano Leporatti,Andrea Ragusa,Rawil Fakhrullin
- Publisher : Frontiers Media SA
- Release Date : 2020-12-31
- ISBN : 9782889663187
Synthesis and application of ?-configured [18/19F]FDGs
- Author : Mathias Elgland
- Publisher : Linköping University Electronic Press
- Release Date : 2018-02-21
- ISBN : 9789176853764
Positron emission tomography (PET) is a non-invasive imaging method that renders three-dimensional images of tissue that selectively has taken up a radiolabelled organic compound, referred to as a radiotracer. This excellent technique provides clinicians with a tool to monitor disease progression and to evaluate how the patient respond to treatment. The by far most widely employed radiotracer in PET is called 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG), which is often referred to as the golden standard in PET. From a
Neurodegenerative Diseases
- Author : Nagehan Ersoy Tunalı
- Publisher : BoD – Books on Demand
- Release Date : 2021-01-20
- ISBN : 9781838801496
Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical
The Alzheimer's Disease Challenge
- Author : Athanasios Alexiou,Mohammad A. Kamal,Ghulam Md Ashraf
- Publisher : Frontiers Media SA
- Release Date : 2019-12-04
- ISBN : 9782889631285
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population
Handbook on Nanobiomaterials for Therapeutics and Diagnostic Applications
- Author : Krishnan Anand,Muthupandian Saravanan,Balakumar Chandrasekaran,Suvardhan Kanchi,Sarojini Jeeva Panchu,Quan-Sheng Chen
- Publisher : Elsevier
- Release Date : 2021-03-18
- ISBN : 9780128219140
Handbook of Nano-biomaterials for Therapeutics and Diagnostic Applications covers in-depth topics on nano-biomaterials and nano drug delivery systems (biosensors and bioimaging) involving polymer nanocomposites, metal nanocomposites, and other carbon family fibers and proteins. The book covers the current application of tiny machines or nanodevices and their use as early detection systems for life threatening diseases, giving detailed literature on the development of nanodevices, their use as diagnostic tools, and their present trend in the industry and market. In addition, their
Novel Bifunctional Compounds as Theranostic Agents for Alzheimer's Disease

- Author : Liang Sun (Chemist)
- Publisher : Unknown
- Release Date : 2019
- ISBN : OCLC:1110621017
Alzheimer's Disease (AD) is the most prevalent neurodegenerative disease, currently affecting 5 million in the US and 25 million population worldwide. Unfortunately, there is no treatment for AD, and its accurate diagnosis requires a detailed post-mortem examination of the brain. The formation of extracellular amyloid plaques containing the amyloid [beta] (A[beta]) peptide is one of the pathological hallmarks in the brains of Alzheimer's patients. In addition, numerous studies show that the metal ions can interact with the A[beta] peptides and