Adenoviral Vectors for Gene Therapy

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Read or download book entitled Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press in PDF, EPUB and Kindle Format. Click Get This Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like. We cannot guarantee that Adenoviral Vectors for Gene Therapy book is available in the library.

  • Publisher : Academic Press
  • Release : 10 March 2016
  • ISBN : 9780128005101
  • Page : 868 pages
  • Rating : 4.5/5 from 103 voters

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Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials

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Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
  • Author : David T. Curiel
  • Publisher : Academic Press
  • Release Date : 2016-03-10
  • ISBN : 9780128005101
GET THIS BOOKAdenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors

Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy
  • Author : David T. Curiel,Joanne T. Douglas
  • Publisher : Academic Press
  • Release Date : 2002-05
  • ISBN : 0121995046
GET THIS BOOKAdenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of

Therapeutic Applications of Adenoviruses

Therapeutic Applications of Adenoviruses
  • Author : Philip Ng,Nicola Brunetti-Pierri
  • Publisher : CRC Press
  • Release Date : 2016-12-12
  • ISBN : 9781498745499
GET THIS BOOKTherapeutic Applications of Adenoviruses

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the

A Guide to Human Gene Therapy

A Guide to Human Gene Therapy
  • Author : Roland W. Herzog,Sergei Zolotukhin
  • Publisher : World Scientific
  • Release Date : 2010
  • ISBN : 9789814280914
GET THIS BOOKA Guide to Human Gene Therapy

1. Non-viral gene therapy / Sean M. Sullivan -- 2. Adenoviral vectors / Stuart A. Nicklin and Andrew H. Baker -- 3. Retroviral vectors and integration analysis / Cynthia C. Bartholomae [und weitere] -- 4. Lentiviral vectors / Janka Matrai, Marinee K.L. Chuah and Thierry VandenDriessche -- 5. Herpes simplex virus vectors / William F. Goins [und weitere] -- 6. Adeno-Associated Viral (AAV) vectors / Nicholas Muzyczka -- 7. Regulatory RNA in gene therapy / Alfred. S. Lewin -- 8. DNA integrating vectors (Transposon, Integrase) / Lauren E. Woodard and Michele P. Calos -- 9. Homologous

Holland-Frei Cancer Medicine

Holland-Frei Cancer Medicine
  • Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
  • Publisher : John Wiley & Sons
  • Release Date : 2017-03-10
  • ISBN : 9781119000846
GET THIS BOOKHolland-Frei Cancer Medicine

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage

Viral Vectors for Gene Therapy

Viral Vectors for Gene Therapy
  • Author : Curtis A. Machida
  • Publisher : Springer Science & Business Media
  • Release Date : 2003
  • ISBN : 9781592593040
GET THIS BOOKViral Vectors for Gene Therapy

Comprehensive and highly practical, Viral Vectors for Gene Therapy provides researchers with the basic tools needed to design targeted gene delivery vectors, and clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders. Offering detailed step-by-step instructions to ensure successful results, these experts detail the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Additional chapters demonstrate the use of

Gene Therapy for Cancer

Gene Therapy for Cancer
  • Author : Kelly K. Hunt,Stephan A. Vorburger,Stephen G. Swisher
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-10-26
  • ISBN : 9781597452229
GET THIS BOOKGene Therapy for Cancer

The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.

Gene Therapy for Diseases of the Lung

Gene Therapy for Diseases of the Lung
  • Author : Kenneth Brigham
  • Publisher : CRC Press
  • Release Date : 1997-04-10
  • ISBN : 0824700600
GET THIS BOOKGene Therapy for Diseases of the Lung

This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.

Viral Vectors for Gene Therapy

Viral Vectors for Gene Therapy
  • Author : Otto-Wilhelm Merten,Mohamed Al-Rubeai
  • Publisher : Humana Press
  • Release Date : 2011-05-19
  • ISBN : 161779094X
GET THIS BOOKViral Vectors for Gene Therapy

The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection. In Viral Vectors for Gene Therapy: Methods and Protocols, experts in the field present a collection of their knowledge and experience featuring methodologies that involve virus production, transferring protocols, and evaluating the efficacy of

Adeno-Associated Virus (AAV) Vectors in Gene Therapy

Adeno-Associated Virus (AAV) Vectors in Gene Therapy
  • Author : Kenneth I. Berns,Catherine Giraud
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • ISBN : 9783642802072
GET THIS BOOKAdeno-Associated Virus (AAV) Vectors in Gene Therapy

Human gene therapy holds great promise for the cure of many genetic diseases. In order to achieve such a cure there are two requirements. First, the affected gene must be cloned, its se quence determined and its regulation adequately characterized. Second, a suitable vector for the delivery of a good copy of the affected gene must be available. For a vector to be of use several attributes are highly desirable: these include ability to carry the intact gene (although this

Therapeutic Applications of Adenoviruses

Therapeutic Applications of Adenoviruses
  • Author : Philip Ng,Nicola Brunetti-Pierri
  • Publisher : CRC Press
  • Release Date : 2016-12-12
  • ISBN : 9781315351803
GET THIS BOOKTherapeutic Applications of Adenoviruses

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the

Novel Technologies for Vaccine Development

Novel Technologies for Vaccine Development
  • Author : Igor S Lukashevich,Haval Shirwan
  • Publisher : Springer
  • Release Date : 2014-11-13
  • ISBN : 9783709118184
GET THIS BOOKNovel Technologies for Vaccine Development

This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and

Viral Vectors for Gene Therapy

Viral Vectors for Gene Therapy
  • Author : Fredric P. Manfredsson,Matthew J. Benskey
  • Publisher : Humana Press
  • Release Date : 2019-02-01
  • ISBN : 1493990640
GET THIS BOOKViral Vectors for Gene Therapy

This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions

Viral Gene Therapy

Viral Gene Therapy
  • Author : Ke Xu
  • Publisher : BoD – Books on Demand
  • Release Date : 2011-07-20
  • ISBN : 9789533075396
GET THIS BOOKViral Gene Therapy

The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy

Encyclopedia of Cancer

Encyclopedia of Cancer
  • Author : Manfred Schwab
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-09-23
  • ISBN : 9783540368472
GET THIS BOOKEncyclopedia of Cancer

This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical